Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response. Desimone MC, Rathmell WK, Threadgill DW (2013) J Natl Cancer Inst 105: 1355-64 Reaction of trichloroethylene and trichloroethylene oxide with cytochrome P450 enzymes: inactivation and sites of modification. Cai H, Guengerich FP (2001) Chem Res Toxicol 14: 451-8 Principles of covalent binding of reactive metabolites and examples of activation of bis-electrophiles by conjugation. Guengerich FP (2005) Arch Biochem Biophys 433: 369-78 Cancer mortality among aircraft manufacturing workers: an extended follow-up. Lipworth L, Sonderman JS, Mumma MT, Tarone RE, Marano DE, Boice JD, McLaughlin JK (2011) J Occup Environ Med 53: 992-1007 Reactive intermediates in biological systems: what have we learned and where are we going? Guengerich FP, Cai H, Johnson WW, Parikh A (2001) Adv Exp Med Biol 500: 639-50
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.