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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Brain Ischemia are shown below. Double-click or tap a node for more information.
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- A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.
Gudbjartsson DF, Holm H, Gretarsdottir S, Thorleifsson G, Walters GB, Thorgeirsson G, Gulcher J, Mathiesen EB, Njølstad I, Nyrnes A, Wilsgaard T, Hald EM, Hveem K, Stoltenberg C, Kucera G, Stubblefield T, Carter S, Roden D, Ng MC, Baum L, So WY, Wong KS, Chan JC, Gieger C, Wichmann HE, Gschwendtner A, Dichgans M, Kuhlenbäumer G, Berger K, Ringelstein EB, Bevan S, Markus HS, Kostulas K, Hillert J, Sveinbjörnsdóttir S, Valdimarsson EM, Løchen ML, Ma RC, Darbar D, Kong A, Arnar DO, Thorsteinsdottir U, Stefansson K
(2009) Nat Genet 41: 876-8 - Stroke: thrombolysis in childhood arterial ischemic stroke.
Jordan LC
(2009) Nat Rev Neurol 5: 473-4 - Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis.
Kleinschnitz C, Stoll G, Bendszus M, Schuh K, Pauer HU, Burfeind P, Renné C, Gailani D, Nieswandt B, Renné T
(2006) J Exp Med 203: 513-8 - BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia.
Plesnila N, Zinkel S, Le DA, Amin-Hanjani S, Wu Y, Qiu J, Chiarugi A, Thomas SS, Kohane DS, Korsmeyer SJ, Moskowitz MA
(2001) Proc Natl Acad Sci U S A 98: 15318-23 - Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study.
Jefferson AL, Massaro JM, Wolf PA, Seshadri S, Au R, Vasan RS, Larson MG, Meigs JB, Keaney JF, Lipinska I, Kathiresan S, Benjamin EJ, DeCarli C
(2007) Neurology 68: 1032-8 - Stroke after trauma in children and young adults: Some opportunity for primary prevention.
Jordan LC, Bhattacharya PD
(2017) Neurology 89: 2306-2307 - Socioeconomic determinants of outcome after childhood arterial ischemic stroke.
Jordan LC, Hills NK, Fox CK, Ichord RN, Pergami P, deVeber GA, Fullerton HJ, Lo W, VIPS Investigators
(2018) Neurology 91: e509-e516 - Deaths from stroke in US children, 1979 to 1998.
Fullerton HJ, Chetkovich DM, Wu YW, Smith WS, Johnston SC
(2002) Neurology 59: 34-9 - Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism.
Jo S, Kalló I, Bardóczi Z, Arrojo e Drigo R, Zeöld A, Liposits Z, Oliva A, Lemmon VP, Bixby JL, Gereben B, Bianco AC
(2012) J Neurosci 32: 8491-500 - Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) study.
Kelly PJ, Morrow JD, Ning M, Koroshetz W, Lo EH, Terry E, Milne GL, Hubbard J, Lee H, Stevenson E, Lederer M, Furie KL
(2008) Stroke 39: 100-4 - Towards a consensus-based classification of childhood arterial ischemic stroke.
Bernard TJ, Manco-Johnson MJ, Lo W, MacKay MT, Ganesan V, DeVeber G, Goldenberg NA, Armstrong-Wells J, Dowling MM, Roach ES, Tripputi M, Fullerton HJ, Furie KL, Benseler SM, Jordan LC, Kirton A, Ichord R
(2012) Stroke 43: 371-7 - Rapid disruption of an astrocyte interaction with the extracellular matrix mediated by integrin alpha 6 beta 4 during focal cerebral ischemia/reperfusion.
Wagner S, Tagaya M, Koziol JA, Quaranta V, del Zoppo GJ
(1997) Stroke 28: 858-65 - Inter-Rater Reliability of the CASCADE Criteria: Challenges in Classifying Arteriopathies.
Bernard TJ, Beslow LA, Manco-Johnson MJ, Armstrong-Wells J, Boada R, Weitzenkamp D, Hollatz A, Poisson S, Amlie-Lefond C, Lo W, deVeber G, Goldenberg NA, Dowling MM, Roach ES, Fullerton HJ, Benseler SM, Jordan LC, Kirton A, Ichord RN
(2016) Stroke 47: 2443-9 - Transient ischemic attack requiring hospitalization of children in the United States: kids' inpatient database 2003 to 2009.
Adil MM, Qureshi AI, Beslow LA, Jordan LC
(2014) Stroke 45: 887-8 - Management of Stroke in Neonates and Children: A Scientific Statement From the American Heart Association/American Stroke Association.
Ferriero DM, Fullerton HJ, Bernard TJ, Billinghurst L, Daniels SR, DeBaun MR, deVeber G, Ichord RN, Jordan LC, Massicotte P, Meldau J, Roach ES, Smith ER, American Heart Association Stroke Council and Council on Cardiovascular and Stroke Nursing
(2019) Stroke 50: e51-e96 - Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management.
Guilliams KP, Kirkham FJ, Holzhauer S, Pavlakis S, Philbrook B, Amlie-Lefond C, Noetzel MJ, Dlamini N, Sharma M, Carpenter JL, Fox CK, Torres M, Ichord RN, Jordan LC, Dowling MM
(2019) Stroke 50: 1089-1094 - Endothelial progenitor cells augment collateralization and hemodynamic rescue in a model of chronic cerebral ischemia.
Hecht N, Schneider UC, Czabanka M, Vinci M, Hatzopoulos AK, Vajkoczy P, Woitzik J
(2014) J Cereb Blood Flow Metab 34: 1297-305 - Prospects for primary stroke prevention in children with sickle cell anaemia.
Jordan LC, Casella JF, DeBaun MR
(2012) Br J Haematol 157: 14-25 - Plasma glial fibrillary acidic protein levels in children with sickle cell disease.
Savage WJ, Barron-Casella E, Fu Z, Dulloor P, Williams L, Crain BJ, White DA, Jennings JM, Van Eyk JE, Debaun MR, Everett A, Casella JF
(2011) Am J Hematol 86: 427-9 - Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels.
de Bilbao F, Arsenijevic D, Vallet P, Hjelle OP, Ottersen OP, Bouras C, Raffin Y, Abou K, Langhans W, Collins S, Plamondon J, Alves-Guerra MC, Haguenauer A, Garcia I, Richard D, Ricquier D, Giannakopoulos P
(2004) J Neurochem 89: 1283-92 - The kinder side of killer proteases: caspase activation contributes to neuroprotection and CNS remodeling.
McLaughlin B
(2004) Apoptosis 9: 111-21 - Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation.
Grelli KN, Palubinsky AM, Kale AC, Lizama-Manibusan BN, Stankowski JN, Milne GL, Singer R, McLaughlin B
(2013) CNS Neurol Disord Drug Targets 12: 849-60 - Imaging of amide proton transfer and nuclear Overhauser enhancement in ischemic stroke with corrections for competing effects.
Li H, Zu Z, Zaiss M, Khan IS, Singer RJ, Gochberg DF, Bachert P, Gore JC, Xu J
(2015) NMR Biomed 28: 200-9 - Spin-lock imaging of early tissue pH changes in ischemic rat brain.
Zu Z, Afzal A, Li H, Xie J, Gore JC
(2018) NMR Biomed 31: e3893 - Oscillating gradient measurements of water diffusion in normal and globally ischemic rat brain.
Does MD, Parsons EC, Gore JC
(2003) Magn Reson Med 49: 206-15 - Compartmental study of diffusion and relaxation measured in vivo in normal and ischemic rat brain and trigeminal nerve.
Does MD, Gore JC
(2000) Magn Reson Med 43: 837-44 - Intraarterial administration of norcantharidin attenuates ischemic stroke damage in rodents when given at the time of reperfusion: novel uses of endovascular capabilities.
Khan IS, Odom M, Ehtesham M, Colvin D, Quarles CC, McLaughlin B, Singer RJ
(2016) J Neurosurg 125: 152-9 - Extension of the neuroprotective time window for thiazolidinediones in ischemic stroke is dependent on time of reperfusion.
Gamboa J, Blankenship DA, Niemi JP, Landreth GE, Karl M, Hilow E, Sundararajan S
(2010) Neuroscience 170: 846-57 - Children with post-stroke epilepsy have poorer outcomes one year after stroke.
Fox CK, Jordan LC, Beslow LA, Armstrong J, Mackay MT, deVeber G
(2018) Int J Stroke 13: 820-823 - Thrombolytics for acute stroke in children: eligibility, practice variability, and pediatric stroke centers.
Jordan LC
(2015) Dev Med Child Neurol 57: 115-6 - Misoprostol, an anti-ulcer agent and PGE2 receptor agonist, protects against cerebral ischemia.
Li J, Liang X, Wang Q, Breyer RM, McCullough L, Andreasson K
(2008) Neurosci Lett 438: 210-5 - The diagnostic value of N-terminal pro-brain natriuretic peptide in differentiating cardioembolic ischemic stroke.
Hajsadeghi S, Kashani Amin L, Bakhshandeh H, Rohani M, Azizian AR, Jafarian Kerman SR
(2013) J Stroke Cerebrovasc Dis 22: 554-60 - Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
Schmidt AF, Holmes MV, Preiss D, Swerdlow DI, Denaxas S, Fatemifar G, Faraway R, Finan C, Valentine D, Fairhurst-Hunter Z, Hartwig FP, Horta BL, Hypponen E, Power C, Moldovan M, van Iperen E, Hovingh K, Demuth I, Norman K, Steinhagen-Thiessen E, Demuth J, Bertram L, Lill CM, Coassin S, Willeit J, Kiechl S, Willeit K, Mason D, Wright J, Morris R, Wanamethee G, Whincup P, Ben-Shlomo Y, McLachlan S, Price JF, Kivimaki M, Welch C, Sanchez-Galvez A, Marques-Vidal P, Nicolaides A, Panayiotou AG, Onland-Moret NC, van der Schouw YT, Matullo G, Fiorito G, Guarrera S, Sacerdote C, Wareham NJ, Langenberg C, Scott RA, Luan J, Bobak M, Malyutina S, Pająk A, Kubinova R, Tamosiunas A, Pikhart H, Grarup N, Pedersen O, Hansen T, Linneberg A, Jess T, Cooper J, Humphries SE, Brilliant M, Kitchner T, Hakonarson H, Carrell DS, McCarty CA, Lester KH, Larson EB, Crosslin DR, de Andrade M, Roden DM, Denny JC, Carty C, Hancock S, Attia J, Holliday E, Scott R, Schofield P, O'Donnell M, Yusuf S, Chong M, Pare G, van der Harst P, Said MA, Eppinga RN, Verweij N, Snieder H, Lifelines Cohort authors, Christen T, Mook-Kanamori DO, ICBP Consortium, Gustafsson S, Lind L, Ingelsson E, Pazoki R, Franco O, Hofman A, Uitterlinden A, Dehghan A, Teumer A, Baumeister S, Dörr M, Lerch MM, Völker U, Völzke H, Ward J, Pell JP, Meade T, Christophersen IE, Maitland-van der Zee AH, Baranova EV, Young R, Ford I, Campbell A, Padmanabhan S, Bots ML, Grobbee DE, Froguel P, Thuillier D, Roussel R, Bonnefond A, Cariou B, Smart M, Bao Y, Kumari M, Mahajan A, Hopewell JC, Seshadri S, METASTROKE Consortium of the ISGC, Dale C, Costa RPE, Ridker PM, Chasman DI, Reiner AP, Ritchie MD, Lange LA, Cornish AJ, Dobbins SE, Hemminki K, Kinnersley B, Sanson M, Labreche K, Simon M, Bondy M, Law P, Speedy H, Allan J, Li N, Went M, Weinhold N, Morgan G, Sonneveld P, Nilsson B, Goldschmidt H, Sud A, Engert A, Hansson M, Hemingway H, Asselbergs FW, Patel RS, Keating BJ, Sattar N, Houlston R, Casas JP, Hingorani AD
(2019) BMC Cardiovasc Disord 19: 240 - Incidence of Epilepsy and Associated Risk Factors in Perinatal Ischemic Stroke Survivors.
Rattani A, Lim J, Mistry AM, Prablek MA, Roth SG, Jordan LC, Shannon CN, Naftel RP
(2019) Pediatr Neurol 90: 44-55 - Hemorrhagic and ischemic stroke in children with cancer.
Noje C, Cohen K, Jordan LC
(2013) Pediatr Neurol 49: 237-42 - Ischemic stroke in children with critical illness: a poor prognostic sign.
Jordan LC, van Beek JG, Gottesman RF, Kossoff EH, Johnston MV
(2007) Pediatr Neurol 36: 244-6 - Arterial Ischemic Stroke Secondary to Cardiac Disease in Neonates and Children.
Chung MG, Guilliams KP, Wilson JL, Beslow LA, Dowling MM, Friedman NR, Hassanein SMA, Ichord R, Jordan LC, Mackay MT, Rafay MF, Rivkin M, Torres M, Zafeiriou D, deVeber G, Fox CK, International Pediatric Stroke Study Investigators
(2019) Pediatr Neurol 100: 35-41 - Neuroprotection by a novel NMDAR functional glycine site partial agonist, GLYX-13.
Stanton PK, Potter PE, Aguilar J, Decandia M, Moskal JR
(2009) Neuroreport 20: 1193-7 - Activation of caspase-12, an endoplasmic reticulum resident caspase, after permanent focal ischemia in rat.
Mouw G, Zechel JL, Gamboa J, Lust WD, Selman WR, Ratcheson RA
(2003) Neuroreport 14: 183-6 - Pediatric stroke: the importance of cerebral arteriopathy and vascular malformations.
Beslow LA, Jordan LC
(2010) Childs Nerv Syst 26: 1263-73
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