The intersection between asthma and acute chest syndrome in children with sickle-cell anaemia. DeBaun MR, Strunk RC (2016) Lancet 387: 2545-53 Elevation of IgE in children with sickle cell disease is associated with doctor diagnosis of asthma and increased morbidity. An P, Barron-Casella EA, Strunk RC, Hamilton RG, Casella JF, DeBaun MR (2011) J Allergy Clin Immunol 127: 1440-6 Smoking is associated with an increased risk of acute chest syndrome and pain among adults with sickle cell disease. Cohen RT, DeBaun MR, Blinder MA, Strunk RC, Field JJ (2010) Blood 115: 3852-4 Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease. Bean CJ, Boulet SL, Ellingsen D, Pyle ME, Barron-Casella EA, Casella JF, Payne AB, Driggers J, Trau HA, Yang G, Jones K, Ofori-Acquah SF, Hooper WC, DeBaun MR (2012) Blood 120: 3822-8 Acute chest syndrome is associated with single nucleotide polymorphism-defined beta globin cluster haplotype in children with sickle cell anaemia. Bean CJ, Boulet SL, Yang G, Payne AB, Ghaji N, Pyle ME, Hooper WC, Bhatnagar P, Keefer J, Barron-Casella EA, Casella JF, Debaun MR (2013) Br J Haematol 163: 268-76 Wheezing and asthma are independent risk factors for increased sickle cell disease morbidity. Glassberg JA, Chow A, Wisnivesky J, Hoffman R, Debaun MR, Richardson LD (2012) Br J Haematol 159: 472-9 Wheezing symptoms and parental asthma are associated with a physician diagnosis of asthma in children with sickle cell anemia. Strunk RC, Cohen RT, Cooper BP, Rodeghier M, Kirkham FJ, Warner JO, Stocks J, Kirkby J, Roberts I, Rosen CL, Craven DI, DeBaun MR, Sleep Asthma Cohort Investigative Team (2014) J Pediatr 164: 821-826.e1 Implementation of multidisciplinary care reduces maternal mortality in women with sickle cell disease living in low-resource setting. Asare EV, Olayemi E, Boafor T, Dei-Adomakoh Y, Mensah E, Ghansah H, Osei-Bonsu Y, Crabbe S, Musah L, Hayfron-Benjamin C, Covert B, Kassim AA, James A, Rodeghier M, DeBaun MR, Oppong SA (2017) Am J Hematol 92: 872-878 Factors predicting future ACS episodes in children with sickle cell anemia. DeBaun MR, Rodeghier M, Cohen R, Kirkham FJ, Rosen CL, Roberts I, Cooper B, Stocks J, Wilkey O, Inusa B, Warner JO, Strunk RC (2014) Am J Hematol 89: E212-7 Increased risk of severe vaso-occlusive episodes after initial acute chest syndrome in children with sickle cell anemia less than 4 years old: Sleep and asthma cohort. Vance LD, Rodeghier M, Cohen RT, Rosen CL, Kirkham FJ, Strunk RC, DeBaun MR (2015) Am J Hematol 90: 371-5 Rapidly progressive acute chest syndrome in individuals with sickle cell anemia: a distinct acute chest syndrome phenotype. Chaturvedi S, Ghafuri DL, Glassberg J, Kassim AA, Rodeghier M, DeBaun MR (2016) Am J Hematol 91: 1185-1190 Recurrent, severe wheezing is associated with morbidity and mortality in adults with sickle cell disease. Cohen RT, Madadi A, Blinder MA, DeBaun MR, Strunk RC, Field JJ (2011) Am J Hematol 86: 756-61 Multi-modal intervention for the inpatient management of sickle cell pain significantly decreases the rate of acute chest syndrome. Reagan MM, DeBaun MR, Frei-Jones MJ (2011) Pediatr Blood Cancer 56: 262-6 Risk factors for increased ED utilization in a multinational cohort of children with sickle cell disease. Glassberg JA, Wang J, Cohen R, Richardson LD, DeBaun MR (2012) Acad Emerg Med 19: 664-72
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