Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3-dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation. Chiang CW, Harris G, Ellig C, Masters SC, Subramanian R, Shenolikar S, Wadzinski BE, Yang E (2001) Blood 97: 1289-97 MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol. Domina AM, Vrana JA, Gregory MA, Hann SR, Craig RW (2004) Oncogene 23: 5301-15 Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A. Bauman AL, Apparsundaram S, Ramamoorthy S, Wadzinski BE, Vaughan RA, Blakely RD (2000) J Neurosci 20: 7571-8 Acetylation of histones associated with the p21WAF1/CIP1 gene by butyrate is not sufficient for p21WAF1/CIP1 gene transcription in human colorectal adenocarcinoma cells. Kobayashi H, Tan EM, Fleming SE (2004) Int J Cancer 109: 207-13 Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation. Wadzinski BE, Wheat WH, Jaspers S, Peruski LF, Lickteig RL, Johnson GL, Klemm DJ (1993) Mol Cell Biol 13: 2822-34 The mechanism of action of cantharidin in smooth muscle. Knapp J, Bokník P, Huke S, Lüss H, Müller FU, Müller T, Nacke P, Schmitz W, Vahlensieck U, Neumann J (1998) Br J Pharmacol 123: 911-9 Distinct protein phosphatase 2A heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and Akt. Van Kanegan MJ, Adams DG, Wadzinski BE, Strack S (2005) J Biol Chem 280: 36029-36 Phosphorylation and regulation of antidepressant-sensitive serotonin transporters. Ramamoorthy S, Giovanetti E, Qian Y, Blakely RD (1998) J Biol Chem 273: 2458-66 Phosphorylation-independent association of CXCR2 with the protein phosphatase 2A core enzyme. Fan GH, Yang W, Sai J, Richmond A (2001) J Biol Chem 276: 16960-8 Novel phosphorylation sites of eukaryotic initiation factor-4F and evidence that phosphorylation stabilizes interactions of the p25 and p220 subunits. Bu X, Haas DW, Hagedorn CH (1993) J Biol Chem 268: 4975-8 Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A. Kray AE, Carter RS, Pennington KN, Gomez RJ, Sanders LE, Llanes JM, Khan WN, Ballard DW, Wadzinski BE (2005) J Biol Chem 280: 35974-82 NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin. Alagarsamy S, Saugstad J, Warren L, Mansuy IM, Gereau RW, Conn PJ (2005) Neuropharmacology 49 Suppl 1: 135-45 Localization of a nuclear serine/threonine protein phosphatase in insulin-secreting INS-1 cells: potential regulation by IL-1beta. Veluthakal R, Wadzinski BE, Kowluru A (2006) Apoptosis 11: 1401-11 Expression of glutathione and gamma-glutamylcysteine synthetase mRNA is Jun dependent. Sekhar KR, Meredith MJ, Kerr LD, Soltaninassab SR, Spitz DR, Xu ZQ, Freeman ML (1997) Biochem Biophys Res Commun 234: 588-93 Parallel purification of three catalytic subunits of the protein serine/threonine phosphatase 2A family (PP2A(C), PP4(C), and PP6(C)) and analysis of the interaction of PP2A(C) with alpha4 protein. Kloeker S, Reed R, McConnell JL, Chang D, Tran K, Westphal RS, Law BK, Colbran RJ, Kamoun M, Campbell KS, Wadzinski BE (2003) Protein Expr Purif 31: 19-33
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