Evidence for a differential avidity model of T cell selection in the thymus. Ashton-Rickardt PG, Bandeira A, Delaney JR, Van Kaer L, Pircher HP, Zinkernagel RM, Tonegawa S (1994) Cell 76: 651-63 Qa-2-dependent selection of CD8alpha/alpha T cell receptor alpha/beta(+) cells in murine intestinal intraepithelial lymphocytes. Das G, Gould DS, Augustine MM, Fragoso G, Sciutto E, Stroynowski I, Van Kaer L, Schust DJ, Ploegh H, Janeway CA, Scitto E (2000) J Exp Med 192: 1521-8 Peptide influences the folding and intracellular transport of free major histocompatibility complex class I heavy chains. Machold RP, Andrée S, Van Kaer L, Ljunggren HG, Ploegh HL (1995) J Exp Med 181: 1111-22 Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo. Kovats S, Grubin CE, Eastman S, deRoos P, Dongre A, Van Kaer L, Rudensky AY (1998) J Exp Med 187: 245-51 A nonpolymorphic major histocompatibility complex class Ib molecule binds a large array of diverse self-peptides. Joyce S, Tabaczewski P, Angeletti RH, Nathenson SG, Stroynowski I (1994) J Exp Med 179: 579-88 Pivotal roles of CD8+ T cells restricted by MHC class I-like molecules in autoimmune diseases. Das G, Das J, Eynott P, Zhang Y, Bothwell AL, Van Kaer L, Shi Y (2006) J Exp Med 203: 2603-11 In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules. Yan J, Parekh VV, Mendez-Fernandez Y, Olivares-Villagómez D, Dragovic S, Hill T, Roopenian DC, Joyce S, Van Kaer L (2006) J Exp Med 203: 647-59 Expansion of natural (NK1+) T cells that express alpha beta T cell receptors in transporters associated with antigen presentation-1 null and thymus leukemia antigen positive mice. Joyce S, Negishi I, Boesteanu A, DeSilva AD, Sharma P, Chorney MJ, Loh DY, Van Kaer L (1996) J Exp Med 184: 1579-84 Vesicular stomatitis virus antigenic octapeptide N52-59 is anchored into the groove of the H-2Kb molecule by the side chains of three amino acids and the main-chain atoms of the amino terminus. Shibata K, Imarai M, van Bleek GM, Joyce S, Nathenson SG (1992) Proc Natl Acad Sci U S A 89: 3135-9 Amino acid substitutions in the floor of the putative antigen-binding site of H-2T22 affect recognition by a gamma delta T-cell receptor. Moriwaki S, Korn BS, Ichikawa Y, van Kaer L, Tonegawa S (1993) Proc Natl Acad Sci U S A 90: 11396-400 Positive selection of self- and alloreactive CD8+ T cells in Tap-1 mutant mice. Aldrich CJ, Ljunggren HG, Van Kaer L, Ashton-Rickardt PG, Tonegawa S, Forman J (1994) Proc Natl Acad Sci U S A 91: 6525-8 Characterization of an incompletely assembled major histocompatibility class I molecule (H-2Kb) associated with unusually long peptides: implications for antigen processing and presentation. Joyce S, Kuzushima K, Kepecs G, Angeletti RH, Nathenson SG (1994) Proc Natl Acad Sci U S A 91: 4145-9 Leukemia inhibitory factor upregulates cytokine expression by a murine stromal cell line enabling the maintenance of highly enriched competitive repopulating stem cells. Szilvassy SJ, Weller KP, Lin W, Sharma AK, Ho AS, Tsukamoto A, Hoffman R, Leiby KR, Gearing DP (1996) Blood 87: 4618-28 Tapasin-/- and TAP1-/- macrophages are deficient in vacuolar alternate class I MHC (MHC-I) processing due to decreased MHC-I stability at phagolysosomal pH. Chefalo PJ, Grandea AG, Van Kaer L, Harding CV (2003) J Immunol 170: 5825-33 Differential requirement for tapasin in the presentation of leader- and insulin-derived peptide antigens to Qa-1b-restricted CTLs. Li L, Sullivan BA, Aldrich CJ, Soloski MJ, Forman J, Grandea AG, Jensen PE, Van Kaer L (2004) J Immunol 173: 3707-15 The alloreactive and self-restricted CD4+ T cell response directed against a single MHC class II/peptide combination. Kovalik JP, Singh N, Mendiratta SK, Martin WD, Ignatowicz L, Van Kaer L (2000) J Immunol 165: 1285-93 ERAAP and tapasin independently edit the amino and carboxyl termini of MHC class I peptides. Kanaseki T, Lind KC, Escobar H, Nagarajan N, Reyes-Vargas E, Rudd B, Rockwood AL, Van Kaer L, Sato N, Delgado JC, Shastri N (2013) J Immunol 191: 1547-55 The H4b minor histocompatibility antigen is caused by a combination of genetically determined and posttranslational modifications. Yadav R, Yoshimura Y, Boesteanu A, Christianson GJ, Ajayi WU, Shashidharamurthy R, Stanic AK, Roopenian DC, Joyce S (2003) J Immunol 170: 5133-42 Tapasin enhances peptide-induced expression of H2-M3 molecules, but is not required for the retention of open conformers. Lybarger L, Yu YY, Chun T, Wang CR, Grandea AG, Van Kaer L, Hansen TH (2001) J Immunol 167: 2097-105 Thermolabile H-2Kb molecules expressed by transporter associated with antigen processing-deficient RMA-S cells are occupied by low-affinity peptides. De Silva AD, Boesteanu A, Song R, Nagy N, Harhaj E, Harding CV, Joyce S (1999) J Immunol 163: 4413-20 Altered expression of Ly49 inhibitory receptors on natural killer cells from MHC class I-deficient mice. Salcedo M, Diehl AD, Olsson-Alheim MY, Sundbäck J, Van Kaer L, Kärre K, Ljunggren HG (1997) J Immunol 158: 3174-80 Hepatocytes express abundant surface class I MHC and efficiently use transporter associated with antigen processing, tapasin, and low molecular weight polypeptide proteasome subunit components of antigen processing and presentation pathway. Chen M, Tabaczewski P, Truscott SM, Van Kaer L, Stroynowski I (2005) J Immunol 175: 1047-55 A molecular basis for how a single TCR interfaces multiple ligands. Boesteanu A, Brehm M, Mylin LM, Christianson GJ, Tevethia SS, Roopenian DC, Joyce S (1998) J Immunol 161: 4719-27 A transcription factor interacting with the class I gene enhancer is inactive in tumorigenic cell lines which suppress major histocompatibility complex class I genes. Henseling U, Schmidt W, Schöler HR, Gruss P, Hatzopoulos AK (1990) Mol Cell Biol 10: 4100-9 Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection. Lee S, Miller SA, Wright DW, Rock MT, Crowe JE (2007) J Virol 81: 2349-58 Chromosomes X, 9, and the H2 locus interact epistatically to control Leishmania major infection. Roberts LJ, Baldwin TM, Speed TP, Handman E, Foote SJ (1999) Eur J Immunol 29: 3047-50 TAP1-deficient mice select a CD8+ T cell repertoire that displays both diversity and peptide specificity. Sandberg JK, Chambers BJ, Van Kaer L, Kärre K, Ljunggren HG (1996) Eur J Immunol 26: 288-93 Differential reactivity of residual CD8+ T lymphocytes in TAP1 and beta 2-microglobulin mutant mice. Ljunggren HG, Van Kaer L, Ashton-Rickardt PG, Tonegawa S, Ploegh HL (1995) Eur J Immunol 25: 174-8 Traffic control of completely assembled MHC class I molecules beyond the endoplasmic reticulum. Joyce S (1997) J Mol Biol 266: 993-1001 Generation of cellular immunity to lymphocytic choriomeningitis virus is independent of CD1d1 expression. Spence PM, Sriram V, Van Kaer L, Hobbs JA, Brutkiewicz RR (2001) Immunology 104: 168-74 Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus. Rutigliano JA, Rock MT, Johnson AK, Crowe JE, Graham BS (2005) Virology 337: 335-43 Peptide dependency of alloreactive CD4+ T cell responses. Mendiratta SK, Kovalik JP, Hong S, Singh N, Martin WD, Van Kaer L (1999) Int Immunol 11: 351-60 The assembly of functional beta(2)-microglobulin-free MHC class I molecules that interact with peptides and CD8(+) T lymphocytes. Schell TD, Mylin LM, Tevethia SS, Joyce S (2002) Int Immunol 14: 775-82 Accessory proteins that control the assembly of MHC molecules with peptides. Van Kaer L (2001) Immunol Res 23: 205-14 Immune recognition, response, and regulation: how T lymphocytes do it. Joyce S (2001) Immunol Res 23: 215-28 Cross-reactivity between human and murine lymphocyte antigens. IV. Reactivity of H-2 alloantisera with HLA-A, B antigens. Quaranta V, Pellegrino MA, Callahan GN, Ferrone S (1981) Immunogenetics 13: 311-7 Point mutations in the beta chain CDR3 can alter the T cell receptor recognition pattern on an MHC class I/peptide complex over a broad interface area. Goyarts EC, Vegh Z, Kalergis AM, Hörig H, Papadopoulos NJ, Young AC, Thomson CT, Chang HC, Joyce S, Nathenson SG (1998) Mol Immunol 35: 593-607 Mapping the orientation of an antigenic peptide bound in the antigen binding groove of H-2Kb using a monoclonal antibody. Joyce S, Sun R, Nathenson SG (1992) Biochem Biophys Res Commun 186: 1449-54 Rejection of grafts with no H-2 disparity in TAP1 mutant mice: CD4 T cells are important effector cells and self H-2b class I molecules are target. Suárez IM, Benvenutti LA, Noronh I, Van Kaer L, Kalil J, Coelho V (2002) Transpl Immunol 9: 101-10
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