Keyword Connections

•  Harold "Bo" Lovvorn

•  Mark de Caestecker

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• de Caestecker Lab

Publications

• Optimising surveillance for relapse of Wilms' tumour.
  Lovvorn HN
  (2018) Lancet Oncol 19: 1006-1007
• Children with idiopathic hemihypertrophy and beckwith-wiedemann syndrome have different constitutional epigenotypes associated with wilms tumor.
  Niemitz EL, Feinberg AP, Brandenburg SA, Grundy PE, DeBaun MR
  (2005) Am J Hum Genet 77: 887-91
• Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting.
  Lee MP, DeBaun MR, Mitsuya K, Galonek HL, Brandenburg S, Oshimura M, Feinberg AP
  (1999) Proc Natl Acad Sci U S A 96: 5203-8
• Reduced expression of the cyclin-dependent kinase inhibitor gene p57KIP2 in Wilms' tumor.
  Thompson JS, Reese KJ, DeBaun MR, Perlman EJ, Feinberg AP
  (1996) Cancer Res 56: 5723-7
• Serine-phosphorylated STAT1 is a prosurvival factor in Wilms' tumor pathogenesis.
  Timofeeva OA, Plisov S, Evseev AA, Peng S, Jose-Kampfner M, Lovvorn HN, Dome JS, Perantoni AO
  (2006) Oncogene 25: 7555-64
• Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors.
  Polosukhina D, Love HD, Correa H, Su Z, Dahlman KB, Pao W, Moses HL, Arteaga CL, Lovvorn HN, Zent R, Clark PE
  (2017) Mol Oncol 11: 405-421
• CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus.
  Murphy AJ, Pierce J, de Caestecker C, Ayers GD, Zhao A, Krebs JR, Saito-Diaz VK, Lee E, Perantoni AO, de Caestecker MP, Lovvorn HN
  (2014) Oncotarget 5: 386-402
• Secondary malignant neoplasms after Wilms tumor: an international collaborative study.
  Breslow NE, Lange JM, Friedman DL, Green DM, Hawkins MM, Murphy MF, Neglia JP, Olsen JH, Peterson SM, Stiller CA, Robison LL
  (2010) Int J Cancer 127: 657-66
• Molecular characterization of Wilms' tumor from a resource-constrained region of sub-Saharan Africa.
  Murphy AJ, Axt JR, de Caestecker C, Pierce J, Correa H, Seeley EH, Caprioli RM, Newton MW, de Caestecker MP, Lovvorn HN
  (2012) Int J Cancer 131: E983-94
• Recent advances in mammalian RNA editing.
  Niswender CM
  (1998) Cell Mol Life Sci 54: 946-64
• β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors.
  Clark PE, Polosukhina D, Love H, Correa H, Coffin C, Perlman EJ, de Caestecker M, Moses HL, Zent R
  (2011) Am J Pathol 179: 3045-55
• Race disparities in peptide profiles of North American and Kenyan Wilms tumor specimens.
  Libes JM, Seeley EH, Li M, Axt JR, Pierce J, Correa H, Newton M, Hansen E, Judd A, McDonald H, Caprioli RM, Naranjo A, Huff V, O'Neill JA, Lovvorn HN, Kenyan Wilms Tumor Consortium
  (2014) J Am Coll Surg 218: 707-20
• Pseudohermaphroditism, glomerulopathy, and Wilms tumor (Drash syndrome): frequency in end-stage renal failure.
  Eddy AA, Mauer SM
  (1985) J Pediatr 106: 584-7
• Risk of cancer during the first four years of life in children from The Beckwith-Wiedemann Syndrome Registry.
  DeBaun MR, Tucker MA
  (1998) J Pediatr 132: 398-400
• Nephromegaly in infancy and early childhood: a risk factor for Wilms tumor in Beckwith-Wiedemann syndrome.
  DeBaun MR, Siegel MJ, Choyke PL
  (1998) J Pediatr 132: 401-4
• A Murine Model of K-RAS and β-Catenin Induced Renal Tumors Expresses High Levels of E2F1 and Resembles Human Wilms Tumor.
  Yi Y, Polosukhina D, Love HD, Hembd A, Pickup M, Moses HL, Lovvorn HN, Zent R, Clark PE
  (2015) J Urol 194: 1762-70
• S1P/S1P2 signaling induces cyclooxygenase-2 expression in Wilms tumor.
  Li MH, Sanchez T, Milne GL, Morrow JD, Hla T, Ferrer F
  (2009) J Urol 181: 1347-52
• Genetic and chromosomal alterations in Kenyan Wilms Tumor.
  Lovvorn HN, Pierce J, Libes J, Li B, Wei Q, Correa H, Gouffon J, Clark PE, Axt JR, Hansen E, Newton M, O'Neill JA, Kenyan Wilms Tumor Consortium
  (2015) Genes Chromosomes Cancer 54: 702-15
• Pulmonary disease after treatment for Wilms tumor: a report from the national wilms tumor long-term follow-up study.
  Green DM, Lange JM, Qu A, Peterson SM, Kalapurakal JA, Stokes DC, Grigoriev YA, Takashima JR, Norkool P, Friedman DL, Breslow NE
  (2013) Pediatr Blood Cancer 60: 1721-6
• Risk factors for abandonment of Wilms tumor therapy in Kenya.
  Libes J, Oruko O, Abdallah F, Githanga J, Ndung'u J, Musimbi J, Njuguna F, Patel K, White J, Axt JR, O'Neill JA, Shrubsole M, Li M, Lovvorn HN
  (2015) Pediatr Blood Cancer 62: 252-256
• Aberrant activation, nuclear localization, and phosphorylation of Yes-associated protein-1 in the embryonic kidney and Wilms tumor.
  Murphy AJ, Pierce J, de Caestecker C, Libes J, Neblett D, de Caestecker M, Perantoni AO, Tanigawa S, Anderson JR, Dome JS, Das A, Carroll TJ, Lovvorn HN
  (2014) Pediatr Blood Cancer 61: 198-205
• Peptide spectra in Wilms tumor that associate with adverse outcomes.
  Murphy AJ, Pierce J, Seeley EH, Sullivan LM, Ruchelli ED, Nance ML, Caprioli RM, Lovvorn HN
  (2015) J Surg Res 196: 332-8
• Race disparities in Wilms tumor incidence and biology.
  Axt J, Murphy AJ, Seeley EH, Martin CA, Taylor C, Pierce J, Caprioli RM, Whiteside M, Lovvorn HN
  (2011) J Surg Res 170: 112-9
• Chromosome telomere integrity of human solid neoplasms.
  Butler MG, Sciadini M, Hedges LK, Schwartz HS
  (1996) Cancer Genet Cytogenet 86: 50-3
• Pharmacologic Inhibition of β-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor.
  Polosukhina D, Love HD, Moses HL, Lee E, Zent R, Clark PE
  (2017) Oncol Res 25: 1653-1664
• Feasibility of partial nephrectomy for Wilms' tumor in children with Beckwith-Wiedemann syndrome who have been screened with abdominal ultrasonography.
  McNeil DE, Langer JC, Choyke P, DeBaun MR
  (2002) J Pediatr Surg 37: 57-60
• Serum hyaluronan and its association with unfavorable histology and aggressiveness of heterotransplanted Wilms' tumor.
  Lovvorn HN, Savani RC, Ruchelli E, Cass DL, Adzick NS
  (2000) J Pediatr Surg 35: 1070-8
• Laparoscopic nephron-sparing resection of synchronous Wilms tumors in a case of hyperplastic perilobar nephroblastomatosis.
  Rauth TP, Slone J, Crane G, Correa H, Friedman DL, Lovvorn HN
  (2011) J Pediatr Surg 46: 983-8
• SIX2 and CITED1, markers of nephronic progenitor self-renewal, remain active in primitive elements of Wilms' tumor.
  Murphy AJ, Pierce J, de Caestecker C, Taylor C, Anderson JR, Perantoni AO, de Caestecker MP, Lovvorn HN
  (2012) J Pediatr Surg 47: 1239-49
• Wilms' tumorigenesis is altered by misexpression of the transcriptional co-activator, CITED1.
  Lovvorn HN, Boyle S, Shi G, Shyr Y, Wills ML, Perantoni AO, de Caestecker M
  (2007) J Pediatr Surg 42: 474-81
• Health disparities among tennessee pediatric renal tumor patients.
  Neuzil K, Apple A, Sybenga A, Chen H, Zhao S, Whiteside M, Correa H, Phelps HM, Lovvorn HN
  (2020) J Pediatr Surg 55: 1081-1087
• FXR1 expression domain in Wilms tumor.
  Phelps HM, Pierce JM, Murphy AJ, Correa H, Qian J, Massion PP, Lovvorn HN
  (2019) J Pediatr Surg 54: 1198-1205
• Wilms tumor survival in Kenya.
  Axt J, Abdallah F, Axt M, Githanga J, Hansen E, Lessan J, Li M, Musimbi J, Mwachiro M, Newton M, Ndung'u J, Njuguna F, Nzioka A, Oruko O, Patel K, Tenge R, Ukoli F, White R, O'Neill JA, Lovvorn HN
  (2013) J Pediatr Surg 48: 1254-62