Cellular protein synthesis and inhibition of cell division are independent of butyrate-induced histone hyperacetylation. Rubenstein P, Sealy L, Marshall S, Chalkley R (1979) Nature 280: 692-3 The effect of sodium butyrate on histone modification. Sealy L, Chalkley R (1978) Cell 14: 115-21 Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion. Byndloss MX, Olsan EE, Rivera-Chávez F, Tiffany CR, Cevallos SA, Lokken KL, Torres TP, Byndloss AJ, Faber F, Gao Y, Litvak Y, Lopez CA, Xu G, Napoli E, Giulivi C, Tsolis RM, Revzin A, Lebrilla CB, Bäumler AJ (2017) Science 357: 570-575 Macrophage expression of peroxisome proliferator-activated receptor-alpha reduces atherosclerosis in low-density lipoprotein receptor-deficient mice. Babaev VR, Ishiguro H, Ding L, Yancey PG, Dove DE, Kovacs WJ, Semenkovich CF, Fazio S, Linton MF (2007) Circulation 116: 1404-12 Genetic Ablation of Butyrate Utilization Attenuates Gastrointestinal Salmonella Disease. Bronner DN, Faber F, Olsan EE, Byndloss MX, Sayed NA, Xu G, Yoo W, Kim D, Ryu S, Lebrilla CB, Bäumler AJ (2018) Cell Host Microbe 23: 266-273.e4 DNA associated with hyperacetylated histone is preferentially digested by DNase I. Sealy L, Chalkley R (1978) Nucleic Acids Res 5: 1863-76 HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability. Krishnan M, Singh AB, Smith JJ, Sharma A, Chen X, Eschrich S, Yeatman TJ, Beauchamp RD, Dhawan P (2010) Oncogene 29: 305-12 Acetylation of histones associated with the p21WAF1/CIP1 gene by butyrate is not sufficient for p21WAF1/CIP1 gene transcription in human colorectal adenocarcinoma cells. Kobayashi H, Tan EM, Fleming SE (2004) Int J Cancer 109: 207-13 Discovery of (R)-2-(6-Methoxynaphthalen-2-yl)butanoic Acid as a Potent and Selective Aldo-keto Reductase 1C3 Inhibitor. Adeniji A, Uddin MJ, Zang T, Tamae D, Wangtrakuldee P, Marnett LJ, Penning TM (2016) J Med Chem 59: 7431-44 Histone hypoacetylation following release of HTC cells from butyrate. Covault J, Sealy L, Schnell R, Shires A, Chalkley R (1982) J Biol Chem 257: 5809-15 Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs of cyclic AMP. Kramer RE, Rainey WE, Funkenstein B, Dee A, Simpson ER, Waterman MR (1984) J Biol Chem 259: 707-13 Differential effects of sodium butyrate and hexamethylene bisacetamide on growth and secretion of cultured human endocrine tumor cells. Parekh D, Ishizuka J, Townsend CM, Haber BE, Beauchamp RD, Rajaraman S, Karp G, Hsieh J, Thompson JC (1991) Arch Surg 126: 467-72 Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3. Park GY, Joo M, Pedchenko T, Blackwell TS, Christman JW (2004) Am J Physiol Lung Cell Mol Physiol 286: L956-62 Modification of histones immediately following synthesis. Sealy L, Chalkley R (1979) Arch Biochem Biophys 197: 78-82 Drug-induced inactivation or gene silencing of class I histone deacetylases suppresses ovarian cancer cell growth: implications for therapy. Khabele D, Son DS, Parl AK, Goldberg GL, Augenlicht LH, Mariadason JM, Rice VM (2007) Cancer Biol Ther 6: 795-801 Sodium butyrate inhibits cell growth and stimulates p21WAF1/CIP1 protein in human colonic adenocarcinoma cells independently of p53 status. Kobayashi H, Tan EM, Fleming SE (2003) Nutr Cancer 46: 202-11 2-Amino-4-bis(aryloxybenzyl)aminobutanoic acids: A novel scaffold for inhibition of ASCT2-mediated glutamine transport. Schulte ML, Khodadadi AB, Cuthbertson ML, Smith JA, Manning HC (2016) Bioorg Med Chem Lett 26: 1044-1047
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.