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  • Rare and low-frequency coding variants alter human adult height.
    Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y, Schurmann C, Highland HM, Rüeger S, Thorleifsson G, Justice AE, Lamparter D, Stirrups KE, Turcot V, Young KL, Winkler TW, Esko T, Karaderi T, Locke AE, Masca NG, Ng MC, Mudgal P, Rivas MA, Vedantam S, Mahajan A, Guo X, Abecasis G, Aben KK, Adair LS, Alam DS, Albrecht E, Allin KH, Allison M, Amouyel P, Appel EV, Arveiler D, Asselbergs FW, Auer PL, Balkau B, Banas B, Bang LE, Benn M, Bergmann S, Bielak LF, Blüher M, Boeing H, Boerwinkle E, Böger CA, Bonnycastle LL, Bork-Jensen J, Bots ML, Bottinger EP, Bowden DW, Brandslund I, Breen G, Brilliant MH, Broer L, Burt AA, Butterworth AS, Carey DJ, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Chowdhury R, Christensen C, Chu AY, Cocca M, Collins FS, Cook JP, Corley J, Galbany JC, Cox AJ, Cuellar-Partida G, Danesh J, Davies G, de Bakker PI, de Borst GJ, de Denus S, de Groot MC, de Mutsert R, Deary IJ, Dedoussis G, Demerath EW, den Hollander AI, Dennis JG, Di Angelantonio E, Drenos F, Du M, Dunning AM, Easton DF, Ebeling T, Edwards TL, Ellinor PT, Elliott P, Evangelou E, Farmaki AE, Faul JD, Feitosa MF, Feng S, Ferrannini E, Ferrario MM, Ferrieres J, Florez JC, Ford I, Fornage M, Franks PW, Frikke-Schmidt R, Galesloot TE, Gan W, Gandin I, Gasparini P, Giedraitis V, Giri A, Girotto G, Gordon SD, Gordon-Larsen P, Gorski M, Grarup N, Grove ML, Gudnason V, Gustafsson S, Hansen T, Harris KM, Harris TB, Hattersley AT, Hayward C, He L, Heid IM, Heikkilä K, Helgeland Ø, Hernesniemi J, Hewitt AW, Hocking LJ, Hollensted M, Holmen OL, Hovingh GK, Howson JM, Hoyng CB, Huang PL, Hveem K, Ikram MA, Ingelsson E, Jackson AU, Jansson JH, Jarvik GP, Jensen GB, Jhun MA, Jia Y, Jiang X, Johansson S, Jørgensen ME, Jørgensen T, Jousilahti P, Jukema JW, Kahali B, Kahn RS, Kähönen M, Kamstrup PR, Kanoni S, Kaprio J, Karaleftheri M, Kardia SL, Karpe F, Kee F, Keeman R, Kiemeney LA, Kitajima H, Kluivers KB, Kocher T, Komulainen P, Kontto J, Kooner JS, Kooperberg C, Kovacs P, Kriebel J, Kuivaniemi H, Küry S, Kuusisto J, La Bianca M, Laakso M, Lakka TA, Lange EM, Lange LA, Langefeld CD, Langenberg C, Larson EB, Lee IT, Lehtimäki T, Lewis CE, Li H, Li J, Li-Gao R, Lin H, Lin LA, Lin X, Lind L, Lindström J, Linneberg A, Liu Y, Liu Y, Lophatananon A, Luan J, Lubitz SA, Lyytikäinen LP, Mackey DA, Madden PA, Manning AK, Männistö S, Marenne G, Marten J, Martin NG, Mazul AL, Meidtner K, Metspalu A, Mitchell P, Mohlke KL, Mook-Kanamori DO, Morgan A, Morris AD, Morris AP, Müller-Nurasyid M, Munroe PB, Nalls MA, Nauck M, Nelson CP, Neville M, Nielsen SF, Nikus K, Njølstad PR, Nordestgaard BG, Ntalla I, O'Connel JR, Oksa H, Loohuis LM, Ophoff RA, Owen KR, Packard CJ, Padmanabhan S, Palmer CN, Pasterkamp G, Patel AP, Pattie A, Pedersen O, Peissig PL, Peloso GM, Pennell CE, Perola M, Perry JA, Perry JR, Person TN, Pirie A, Polasek O, Posthuma D, Raitakari OT, Rasheed A, Rauramaa R, Reilly DF, Reiner AP, Renström F, Ridker PM, Rioux JD, Robertson N, Robino A, Rolandsson O, Rudan I, Ruth KS, Saleheen D, Salomaa V, Samani NJ, Sandow K, Sapkota Y, Sattar N, Schmidt MK, Schreiner PJ, Schulze MB, Scott RA, Segura-Lepe MP, Shah S, Sim X, Sivapalaratnam S, Small KS, Smith AV, Smith JA, Southam L, Spector TD, Speliotes EK, Starr JM, Steinthorsdottir V, Stringham HM, Stumvoll M, Surendran P, 't Hart LM, Tansey KE, Tardif JC, Taylor KD, Teumer A, Thompson DJ, Thorsteinsdottir U, Thuesen BH, Tönjes A, Tromp G, Trompet S, Tsafantakis E, Tuomilehto J, Tybjaerg-Hansen A, Tyrer JP, Uher R, Uitterlinden AG, Ulivi S, van der Laan SW, Van Der Leij AR, van Duijn CM, van Schoor NM, van Setten J, Varbo A, Varga TV, Varma R, Edwards DR, Vermeulen SH, Vestergaard H, Vitart V, Vogt TF, Vozzi D, Walker M, Wang F, Wang CA, Wang S, Wang Y, Wareham NJ, Warren HR, Wessel J, Willems SM, Wilson JG, Witte DR, Woods MO, Wu Y, Yaghootkar H, Yao J, Yao P, Yerges-Armstrong LM, Young R, Zeggini E, Zhan X, Zhang W, Zhao JH, Zhao W, Zhao W, Zheng H, Zhou W, EPIC-InterAct Consortium, CHD Exome+ Consortium, ExomeBP Consortium, T2D-Genes Consortium, GoT2D Genes Consortium, Global Lipids Genetics Consortium, ReproGen Consortium, MAGIC Investigators, Rotter JI, Boehnke M, Kathiresan S, McCarthy MI, Willer CJ, Stefansson K, Borecki IB, Liu DJ, North KE, Heard-Costa NL, Pers TH, Lindgren CM, Oxvig C, Kutalik Z, Rivadeneira F, Loos RJ, Frayling TM, Hirschhorn JN, Deloukas P, Lettre G
    (2017) Nature 542: 186-190
  • Linkage disequilibrium in the human insulin/insulin-like growth factor II region of human chromosome II.
    Cox NJ, Bell GI, Xiang KS
    (1988) Am J Hum Genet 43: 495-501
  • Expression of insulin-like growth factor-I and -II genes in human smooth muscle tumours.
    Höppener JW, Mosselman S, Roholl PJ, Lambrechts C, Slebos RJ, de Pagter-Holthuizen P, Lips CJ, Jansz HS, Sussenbach JS
    (1988) EMBO J 7: 1379-85
  • Inhibition of the mitogenic effects of plasma by a monoclonal antibody to somatomedin C.
    Russell WE, Van Wyk JJ, Pledger WJ
    (1984) Proc Natl Acad Sci U S A 81: 2389-92
  • Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation.
    Triplett TA, Cardenas KT, Lancaster JN, Hu Z, Selden HJ, Jasso GJ, Balasubramanyam S, Chan K, Li L, Chen X, Marcogliese AN, Davé UP, Love PE, Ehrlich LI
    (2016) Proc Natl Acad Sci U S A 113: E1016-25
  • Synthetic somatomedin C: comparison with natural hormone isolated from human plasma.
    Van Wyk JJ, Russell WE, Li CH
    (1984) Proc Natl Acad Sci U S A 81: 740-2
  • Apa I and Sst I RFLPs at the insulin-like growth factor II (IGF2) locus on chromosome 11.
    Xiang K, Cox NJ, Bell GI
    (1988) Nucleic Acids Res 16: 3599
  • Growth hormone, somatomedins, and the liver.
    Russell WE
    (1985) Semin Liver Dis 5: 46-58
  • Prospects and challenges for the development of new therapies for Ewing sarcoma.
    Grohar PJ, Helman LJ
    (2013) Pharmacol Ther 137: 216-24
  • BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma.
    Loganathan SN, Tang N, Fleming JT, Ma Y, Guo Y, Borinstein SC, Chiang C, Wang J
    (2016) Oncotarget 7: 43504-43517
  • Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation.
    Gong Y, Ma Y, Sinyuk M, Loganathan S, Thompson RC, Sarkaria JN, Chen W, Lathia JD, Mobley BC, Clark SW, Wang J
    (2016) Neuro Oncol 18: 48-57
  • Repair of metabolic processes.
    Shipman J, Guy J, Abumrad NN
    (2003) Crit Care Med 31: S512-7
  • Joint effect of insulin-like growth factors and sex steroids on breast cancer risk.
    Yu H, Shu XO, Li BD, Dai Q, Gao YT, Jin F, Zheng W
    (2003) Cancer Epidemiol Biomarkers Prev 12: 1067-73
  • Interference of the IGF system as a strategy to inhibit breast cancer growth.
    Arteaga CL
    (1992) Breast Cancer Res Treat 22: 101-6
  • Expression of insulin-like growth factor-I and -II genes in rat medullary thyroid carcinoma.
    Höppener JW, Steenbergh PH, Slebos RJ, de Pagter-Holthuizen P, Roos BA, Jansen M, Van den Brande JL, Sussenbach JS, Jansz HS, Lips CJ
    (1987) FEBS Lett 215: 122-6
  • Absence of ultradian rhythm or diurnal variation in insulin-like growth factor-I in rats.
    Donaghue KC, Badger TM, Millard WJ, Frisch LS, Russell WE
    (1990) Neuroendocrinology 52: 1-8
  • Expression of a biologically active analogue of somatomedin-C/insulin-like growth factor I.
    Peters MA, Lau EP, Snitman DL, Van Wyk JJ, Underwood LE, Russell WE, Svoboda ME
    (1985) Gene 35: 83-9
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