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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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- Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes.
Tam OH, Aravin AA, Stein P, Girard A, Murchison EP, Cheloufi S, Hodges E, Anger M, Sachidanandam R, Schultz RM, Hannon GJ
(2008) Nature 453: 534-8 - microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells.
Marcais A, Blevins R, Graumann J, Feytout A, Dharmalingam G, Carroll T, Amado IF, Bruno L, Lee K, Walzer T, Mann M, Freitas AA, Boothby M, Fisher AG, Merkenschlager M
(2014) J Exp Med 211: 2281-95 - Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells.
Mudhasani R, Zhu Z, Hutvagner G, Eischen CM, Lyle S, Hall LL, Lawrence JB, Imbalzano AN, Jones SN
(2008) J Cell Biol 181: 1055-63 - Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture.
Wohl SG, Jorstad NL, Levine EM, Reh TA
(2017) Nat Commun 8: 1603 - The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles.
Andl T, Murchison EP, Liu F, Zhang Y, Yunta-Gonzalez M, Tobias JW, Andl CD, Seykora JT, Hannon GJ, Millar SE
(2006) Curr Biol 16: 1041-9 - Targeted deletion of Dicer from proximal tubules protects against renal ischemia-reperfusion injury.
Wei Q, Bhatt K, He HZ, Mi QS, Haase VH, Dong Z
(2010) J Am Soc Nephrol 21: 756-61 - Inactivation of p53 is insufficient to allow B cells and B-cell lymphomas to survive without Dicer.
Adams CM, Eischen CM
(2014) Cancer Res 74: 3923-34 - MicroRNA biogenesis is required for Myc-induced B-cell lymphoma development and survival.
Arrate MP, Vincent T, Odvody J, Kar R, Jones SN, Eischen CM
(2010) Cancer Res 70: 6083-92 - Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin.
Teta M, Choi YS, Okegbe T, Wong G, Tam OH, Chong MM, Seykora JT, Nagy A, Littman DR, Andl T, Millar SE
(2012) Development 139: 1405-16 - Gonadotrope-specific deletion of Dicer results in severely suppressed gonadotropins and fertility defects.
Wang H, Graham I, Hastings R, Gunewardena S, Brinkmeier ML, Conn PM, Camper SA, Kumar TR
(2015) J Biol Chem 290: 2699-714 - The regulatory effect of miRNAs is a heritable genetic trait in humans.
Geeleher P, Huang SR, Gamazon ER, Golden A, Seoighe C
(2012) BMC Genomics 13: 383 - Dynamic miRNA expression patterns during retinal regeneration in zebrafish: reduced dicer or miRNA expression suppresses proliferation of Müller glia-derived neuronal progenitor cells.
Rajaram K, Harding RL, Bailey T, Patton JG, Hyde DR
(2014) Dev Dyn 243: 1591-605 - Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome.
Gelfand BD, Wright CB, Kim Y, Yasuma T, Yasuma R, Li S, Fowler BJ, Bastos-Carvalho A, Kerur N, Uittenbogaard A, Han YS, Lou D, Kleinman ME, McDonald WH, Núñez G, Georgel P, Dunaief JL, Ambati J
(2015) Cell Rep 11: 1686-93
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