cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism. Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA (2005) Circ Res 96: 100-9 Activation of amino-alpha-carboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes. Shimada T, Guengerich FP (1991) Cancer Res 51: 5284-91 Phosphodiesterase 5 inhibition improves beta-cell function in metabolic syndrome. Hill KD, Eckhauser AW, Marney A, Brown NJ (2009) Diabetes Care 32: 857-9 Tolerability and safety of alosetron during long-term administration in female and male irritable bowel syndrome patients. Wolfe SG, Chey WY, Washington MK, Harding J, Heath AT, McSorley DJ, Dukes GE, Hunt CM (2001) Am J Gastroenterol 96: 803-11 The effects of tadalafil on cold-induced vasoconstriction in patients with Raynaud's phenomenon. Friedman EA, Harris PA, Wood AJ, Stein CM, Kurnik D (2007) Clin Pharmacol Ther 81: 503-9 Stress selectively increases fos protein in dopamine neurons innervating the prefrontal cortex. Deutch AY, Lee MC, Gillham MH, Cameron DA, Goldstein M, Iadarola MJ (1991) Cereb Cortex 1: 273-92 Stress and the mesocorticolimbic dopamine systems. Roth RH, Tam SY, Ida Y, Yang JX, Deutch AY (1988) Ann N Y Acad Sci 537: 138-47 5-Hydroxytryptamine2C receptor contribution to m-chlorophenylpiperazine and N-methyl-beta-carboline-3-carboxamide-induced anxiety-like behavior and limbic brain activation. Hackler EA, Turner GH, Gresch PJ, Sengupta S, Deutch AY, Avison MJ, Gore JC, Sanders-Bush E (2007) J Pharmacol Exp Ther 320: 1023-9 Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay. Aryal P, Terashita T, Guengerich FP, Shimada T, Oda Y (2000) Environ Mol Mutagen 36: 121-6 The anxiogenic beta-carboline FG-7142 increases in vivo and in vitro tyrosine hydroxylation in the prefrontal cortex. Knorr AM, Deutch AY, Roth RH (1989) Brain Res 495: 355-61
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