cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism. Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA (2005) Circ Res 96: 100-9 The effects of tadalafil on cold-induced vasoconstriction in patients with Raynaud's phenomenon. Friedman EA, Harris PA, Wood AJ, Stein CM, Kurnik D (2007) Clin Pharmacol Ther 81: 503-9 Evidence that additional mechanisms to cyclic GMP mediate the decrease in intracellular calcium and relaxation of rabbit aortic smooth muscle to nitric oxide. Weisbrod RM, Griswold MC, Yaghoubi M, Komalavilas P, Lincoln TM, Cohen RA (1998) Br J Pharmacol 125: 1695-707 A site on transducin alpha-subunit of interaction with the polycationic region of cGMP phosphodiesterase inhibitory subunit. Artemyev NO, Mills JS, Thornburg KR, Knapp DR, Schey KL, Hamm HE (1993) J Biol Chem 268: 23611-5 Subunit structure of rod cGMP-phosphodiesterase. Artemyev NO, Surendran R, Lee JC, Hamm HE (1996) J Biol Chem 271: 25382-8 A monoclonal antibody against the rod outer segment guanyl nucleotide-binding protein, transducin, blocks the stimulatory and inhibitory G proteins of adenylate cyclase. Hamm HE, Deretic D, Mazzoni MR, Moore CA, Takahashi JS, Rasenick MM (1989) J Biol Chem 264: 11475-82 The carboxyl terminus of the gamma-subunit of rod cGMP phosphodiesterase contains distinct sites of interaction with the enzyme catalytic subunits and the alpha-subunit of transducin. Skiba NP, Artemyev NO, Hamm HE (1995) J Biol Chem 270: 13210-5 Sites of interaction between rod G-protein alpha-subunit and cGMP-phosphodiesterase gamma-subunit. Implications for the phosphodiesterase activation mechanism. Artemyev NO, Rarick HM, Mills JS, Skiba NP, Hamm HE (1992) J Biol Chem 267: 25067-72 Mechanism of action of monoclonal antibodies that block the light activation of the guanyl nucleotide-binding protein, transducin. Hamm HE, Deretic D, Hofmann KP, Schleicher A, Kohl B (1987) J Biol Chem 262: 10831-8 Regulation of transducin GTPase activity in bovine rod outer segments. Arshavsky VY, Dumke CL, Zhu Y, Artemyev NO, Skiba NP, Hamm HE, Bownds MD (1994) J Biol Chem 269: 19882-7 Activation of transducin guanosine triphosphatase by two proteins of the RGS family. Nekrasova ER, Berman DM, Rustandi RR, Hamm HE, Gilman AG, Arshavsky VY (1997) Biochemistry 36: 7638-43 Arrestin with a single amino acid substitution quenches light-activated rhodopsin in a phosphorylation-independent fashion. Gray-Keller MP, Detwiler PB, Benovic JL, Gurevich VV (1997) Biochemistry 36: 7058-63 Stimulation of serotonin transport by the cyclic GMP phosphodiesterase-5 inhibitor sildenafil. Zhu CB, Hewlett WA, Francis SH, Corbin JD, Blakely RD (2004) Eur J Pharmacol 504: 1-6 Specific peptide probes for G-protein interaction with effectors. Rarick HM, Artemyev NO, Mills JS, Skiba NP, Hamm HE (1994) Methods Enzymol 238: 13-28 Elevation of cGMP with normal expression and activity of rod cGMP-PDE in photoreceptor degenerate labrador retrievers. Kommonen B, Kylma T, Cohen RJ, Penn JS, Paulin L, Hurwitz M, Hurwitz RL (1996) Ophthalmic Res 28: 19-28
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