In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis. Gargiulo G, Cesaroni M, Serresi M, de Vries N, Hulsman D, Bruggeman SW, Lancini C, van Lohuizen M (2013) Cancer Cell 23: 660-76 Endoplasmic reticulum stress and hypertension - a new paradigm? Hasty AH, Harrison DG (2012) J Clin Invest 122: 3859-61 Endoplasmic reticulum stress in the pathogenesis of fibrotic disease. Kropski JA, Blackwell TS (2018) J Clin Invest 128: 64-73 Epidermal growth factor receptor inhibition slows progression of diabetic nephropathy in association with a decrease in endoplasmic reticulum stress and an increase in autophagy. Zhang MZ, Wang Y, Paueksakon P, Harris RC (2014) Diabetes 63: 2063-72 FGF1 Mediates Overnutrition-Induced Compensatory β-Cell Differentiation. Li M, Page-McCaw P, Chen W (2016) Diabetes 65: 96-109 Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis. Anderson EK, Hill AA, Hasty AH (2012) Arterioscler Thromb Vasc Biol 32: 1687-95 Jnk1 Deficiency in Hematopoietic Cells Suppresses Macrophage Apoptosis and Increases Atherosclerosis in Low-Density Lipoprotein Receptor Null Mice. Babaev VR, Yeung M, Erbay E, Ding L, Zhang Y, May JM, Fazio S, Hotamisligil GS, Linton MF (2016) Arterioscler Thromb Vasc Biol 36: 1122-31 Role of α-crystallin B as a regulatory switch in modulating cardiomyocyte apoptosis by mitochondria or endoplasmic reticulum during cardiac hypertrophy and myocardial infarction. Mitra A, Basak T, Datta K, Naskar S, Sengupta S, Sarkar S (2013) Cell Death Dis 4: e582 ADAR1 is essential for intestinal homeostasis and stem cell maintenance. Qiu W, Wang X, Buchanan M, He K, Sharma R, Zhang L, Wang Q, Yu J (2013) Cell Death Dis 4: e599 The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis. Melville DB, Montero-Balaguer M, Levic DS, Bradley K, Smith JR, Hatzopoulos AK, Knapik EW (2011) Dis Model Mech 4: 763-76 Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis. Kropski JA, Lawson WE, Young LR, Blackwell TS (2013) Dis Model Mech 6: 9-17 Anks4b, a novel target of HNF4α protein, interacts with GRP78 protein and regulates endoplasmic reticulum stress-induced apoptosis in pancreatic β-cells. Sato Y, Hatta M, Karim MF, Sawa T, Wei FY, Sato S, Magnuson MA, Gonzalez FJ, Tomizawa K, Akaike T, Yoshizawa T, Yamagata K (2012) J Biol Chem 287: 23236-45 Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells. Leamy AK, Egnatchik RA, Shiota M, Ivanova PT, Myers DS, Brown HA, Young JD (2014) J Lipid Res 55: 1478-88 Cross-compartment proteostasis regulation during redox imbalance induced ER stress. Maity S, Basak T, Bhat A, Bhasin N, Ghosh A, Chakraborty K, Sengupta S (2014) Proteomics 14: 1724-36 Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways. Chang J, Xue M, Yang S, Yao B, Zhang B, Chen X, Pozzi A, Zhang MZ (2015) PLoS One 10: e0127030 Macrophage Apoptosis and Efferocytosis in the Pathogenesis of Atherosclerosis. Linton MF, Babaev VR, Huang J, Linton EF, Tao H, Yancey PG (2016) Circ J 80: 2259-2268 Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis. Tanjore H, Blackwell TS, Lawson WE (2012) Am J Physiol Lung Cell Mol Physiol 302: L721-9 Right place, right time: the evolving role of herpesvirus infection as a "second hit" in idiopathic pulmonary fibrosis. Kropski JA, Lawson WE, Blackwell TS (2012) Am J Physiol Lung Cell Mol Physiol 302: L441-4 Retention of sedentary obese visceral white adipose tissue phenotype with intermittent physical activity despite reduced adiposity. Wainright KS, Fleming NJ, Rowles JL, Welly RJ, Zidon TM, Park YM, Gaines TL, Scroggins RJ, Anderson-Baucum EK, Hasty AH, Vieira-Potter VJ, Padilla J (2015) Am J Physiol Regul Integr Comp Physiol 309: R594-602 Bioactive aldehyde-modified phosphatidylethanolamines. Guo L, Davies SS (2013) Biochimie 95: 74-8
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