Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses. Ramikie TS, Nyilas R, Bluett RJ, Gamble-George JC, Hartley ND, Mackie K, Watanabe M, Katona I, Patel S (2014) Neuron 81: 1111-1125 Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions. Nair KS, Hanson SM, Mendez A, Gurevich EV, Kennedy MJ, Shestopalov VI, Vishnivetskiy SA, Chen J, Hurley JB, Gurevich VV, Slepak VZ (2005) Neuron 46: 555-67 Lentiviral overexpression of GRK6 alleviates L-dopa-induced dyskinesia in experimental Parkinson's disease. Ahmed MR, Berthet A, Bychkov E, Porras G, Li Q, Bioulac BH, Carl YT, Bloch B, Kook S, Aubert I, Dovero S, Doudnikoff E, Gurevich VV, Gurevich EV, Bezard E (2010) Sci Transl Med 2: 28ra28 Enhanced arrestin facilitates recovery and protects rods lacking rhodopsin phosphorylation. Song X, Vishnivetskiy SA, Gross OP, Emelianoff K, Mendez A, Chen J, Gurevich EV, Burns ME, Gurevich VV (2009) Curr Biol 19: 700-5 siRNA-mediated off-target gene silencing triggered by a 7 nt complementation. Lin X, Ruan X, Anderson MG, McDowell JA, Kroeger PE, Fesik SW, Shen Y (2005) Nucleic Acids Res 33: 4527-35 G protein-coupled receptor kinases: more than just kinases and not only for GPCRs. Gurevich EV, Tesmer JJ, Mushegian A, Gurevich VV (2012) Pharmacol Ther 133: 40-69 Custom-designed proteins as novel therapeutic tools? The case of arrestins. Gurevich VV, Gurevich EV (2010) Expert Rev Mol Med 12: e13 Arrestins and two receptor kinases are upregulated in Parkinson's disease with dementia. Bychkov ER, Gurevich VV, Joyce JN, Benovic JL, Gurevich EV (2008) Neurobiol Aging 29: 379-96 Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder. Bychkov ER, Ahmed MR, Gurevich VV, Benovic JL, Gurevich EV (2011) Neurobiol Dis 44: 248-58 L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain. Bezard E, Gross CE, Qin L, Gurevich VV, Benovic JL, Gurevich EV (2005) Neurobiol Dis 18: 323-35 Analyzing the roles of multi-functional proteins in cells: The case of arrestins and GRKs. Gurevich VV, Gurevich EV (2015) Crit Rev Biochem Mol Biol 50: 440-52 The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions. Raghuwanshi SK, Su Y, Singh V, Haynes K, Richmond A, Richardson RM (2012) J Immunol 189: 2824-32 A novel experimental strategy to assess the metabolic effects of selective activation of a G(q)-coupled receptor in hepatocytes in vivo. Li JH, Jain S, McMillin SM, Cui Y, Gautam D, Sakamoto W, Lu H, Jou W, McGuinness OP, Gavrilova O, Wess J (2013) Endocrinology 154: 3539-51 mu-Opioid receptors desensitize less rapidly than delta-opioid receptors due to less efficient activation of arrestin. Lowe JD, Celver JP, Gurevich VV, Chavkin C (2002) J Biol Chem 277: 15729-35 The selectivity of visual arrestin for light-activated phosphorhodopsin is controlled by multiple nonredundant mechanisms. Gurevich VV (1998) J Biol Chem 273: 15501-6 Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytes. Celver JP, Lowe J, Kovoor A, Gurevich VV, Chavkin C (2001) J Biol Chem 276: 4894-900 Phospholipid-stimulated autophosphorylation activates the G protein-coupled receptor kinase GRK5. Kunapuli P, Gurevich VV, Benovic JL (1994) J Biol Chem 269: 10209-12 G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs). Li L, Homan KT, Vishnivetskiy SA, Manglik A, Tesmer JJ, Gurevich VV, Gurevich EV (2015) J Biol Chem 290: 10775-90 Regulation of arrestin binding by rhodopsin phosphorylation level. Vishnivetskiy SA, Raman D, Wei J, Kennedy MJ, Hurley JB, Gurevich VV (2007) J Biol Chem 282: 32075-83 Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding. Bayburt TH, Vishnivetskiy SA, McLean MA, Morizumi T, Huang CC, Tesmer JJ, Ernst OP, Sligar SG, Gurevich VV (2011) J Biol Chem 286: 1420-8 Mechanism of quenching of phototransduction. Binding competition between arrestin and transducin for phosphorhodopsin. Krupnick JG, Gurevich VV, Benovic JL (1997) J Biol Chem 272: 18125-31 G protein-coupled receptor kinases as regulators of dopamine receptor functions. Gurevich EV, Gainetdinov RR, Gurevich VV (2016) Pharmacol Res 111: 1-16 Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding. Vishnivetskiy SA, Ostermaier MK, Singhal A, Panneels V, Homan KT, Glukhova A, Sligar SG, Tesmer JJ, Schertler GF, Standfuss J, Gurevich VV (2013) Cell Signal 25: 2155-62 The structural basis of the arrestin binding to GPCRs. Gurevich VV, Gurevich EV (2019) Mol Cell Endocrinol 484: 34-41 Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment. Ahmed MR, Bychkov E, Gurevich VV, Benovic JL, Gurevich EV (2008) J Neurochem 104: 1622-36 Arrestin2 expression selectively increases during neural differentiation. Gurevich EV, Benovic JL, Gurevich VV (2004) J Neurochem 91: 1404-16 Abnormalities in renal dopamine signaling and hypertension: the role of GRK4. Harris RC (2012) Curr Opin Nephrol Hypertens 21: 61-5 Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and extracellular signal-regulated kinase activation. Ahmed MR, Gurevich VV, Dalby KN, Benovic JL, Gurevich EV (2008) J Pharmacol Exp Ther 325: 276-83
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