Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia. DeBaun MR, Gordon M, McKinstry RC, Noetzel MJ, White DA, Sarnaik SA, Meier ER, Howard TH, Majumdar S, Inusa BP, Telfer PT, Kirby-Allen M, McCavit TL, Kamdem A, Airewele G, Woods GM, Berman B, Panepinto JA, Fuh BR, Kwiatkowski JL, King AA, Fixler JM, Rhodes MM, Thompson AA, Heiny ME, Redding-Lallinger RC, Kirkham FJ, Dixon N, Gonzalez CE, Kalinyak KA, Quinn CT, Strouse JJ, Miller JP, Lehmann H, Kraut MA, Ball WS, Hirtz D, Casella JF (2014) N Engl J Med 371: 699-710 Transfusions for silent cerebral infarcts in sickle cell anemia. DeBaun MR, Casella JF (2014) N Engl J Med 371: 1841-2 New option for primary stroke prevention in sickle cell anaemia. DeBaun MR, Kirkham FJ (2016) Lancet 387: 626-7 Perspective: thinking beyond survival. DeBaun MR (2014) Nature 515: S16 The challenge of creating an evidence-based guideline for sickle cell disease. DeBaun MR (2014) JAMA 312: 1004-5 Factor V Leiden protects against blood loss and transfusion after cardiac surgery. Donahue BS, Gailani D, Higgins MS, Drinkwater DC, George AL (2003) Circulation 107: 1003-8 Elevation of IgE in children with sickle cell disease is associated with doctor diagnosis of asthma and increased morbidity. An P, Barron-Casella EA, Strunk RC, Hamilton RG, Casella JF, DeBaun MR (2011) J Allergy Clin Immunol 127: 1440-6 Transfusion-related acute lung injury in the critically ill: prospective nested case-control study. Gajic O, Rana R, Winters JL, Yilmaz M, Mendez JL, Rickman OB, O'Byrne MM, Evenson LK, Malinchoc M, DeGoey SR, Afessa B, Hubmayr RD, Moore SB (2007) Am J Respir Crit Care Med 176: 886-91 Associated risk factors for silent cerebral infarcts in sickle cell anemia: low baseline hemoglobin, sex, and relative high systolic blood pressure. DeBaun MR, Sarnaik SA, Rodeghier MJ, Minniti CP, Howard TH, Iyer RV, Inusa B, Telfer PT, Kirby-Allen M, Quinn CT, Bernaudin F, Airewele G, Woods GM, Panepinto JA, Fuh B, Kwiatkowski JK, King AA, Rhodes MM, Thompson AA, Heiny ME, Redding-Lallinger RC, Kirkham FJ, Sabio H, Gonzalez CE, Saccente SL, Kalinyak KA, Strouse JJ, Fixler JM, Gordon MO, Miller JP, Noetzel MJ, Ichord RN, Casella JF (2012) Blood 119: 3684-90 Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease. Hulbert ML, McKinstry RC, Lacey JL, Moran CJ, Panepinto JA, Thompson AA, Sarnaik SA, Woods GM, Casella JF, Inusa B, Howard J, Kirkham FJ, Anie KA, Mullin JE, Ichord R, Noetzel M, Yan Y, Rodeghier M, Debaun MR (2011) Blood 117: 772-9 Longitudinal changes in brain magnetic resonance imaging findings in children with sickle cell disease. Pegelow CH, Macklin EA, Moser FG, Wang WC, Bello JA, Miller ST, Vichinsky EP, DeBaun MR, Guarini L, Zimmerman RA, Younkin DP, Gallagher DM, Kinney TR (2002) Blood 99: 3014-8 Contribution of endogenous bradykinin to fibrinolysis, inflammation, and blood product transfusion following cardiac surgery: a randomized clinical trial. Balaguer JM, Yu C, Byrne JG, Ball SK, Petracek MR, Brown NJ, Pretorius M (2013) Clin Pharmacol Ther 93: 326-34 Comparative effects of angiotensin receptor blockade and ACE inhibition on the fibrinolytic and inflammatory responses to cardiopulmonary bypass. Billings FT, Balaguer JM, C Y, Wright P, Petracek MR, Byrne JG, Brown NJ, Pretorius M (2012) Clin Pharmacol Ther 91: 1065-73 Low-dose recombinant human erythropoietin therapy in chronic hemodialysis patients. Duff DR, Golper TA, Sloan RS, Brier ME, Aronoff GR (1991) Am J Kidney Dis 18: 60-4 The influence of autologous lymphokine-activated killer cell infusions on the toxicity and antitumor effect of repetitive cycles of interleukin-2. Albertini MR, Sosman JA, Hank JA, Moore KH, Borchert A, Schell K, Kohler PC, Bechhofer R, Storer B, Sondel PM (1990) Cancer 66: 2457-64 Magnetic resonance angiography-defined intracranial vasculopathy is associated with silent cerebral infarcts and glucose-6-phosphate dehydrogenase mutation in children with sickle cell anaemia. Thangarajh M, Yang G, Fuchs D, Ponisio MR, McKinstry RC, Jaju A, Noetzel MJ, Casella JF, Barron-Casella E, Hooper WC, Boulet SL, Bean CJ, Pyle ME, Payne AB, Driggers J, Trau HA, Vendt BA, Rodeghier M, DeBaun MR (2012) Br J Haematol 159: 352-9 Prospects for primary stroke prevention in children with sickle cell anaemia. Jordan LC, Casella JF, DeBaun MR (2012) Br J Haematol 157: 14-25 In vivo activation of lymphokine-activated killer activity with interleukin-2: prospects for combination therapies. Sosman JA, Hank JA, Sondel PM (1990) Semin Oncol 17: 22-30; discussion 38-41 Exchange blood transfusion compared with simple transfusion for first overt stroke is associated with a lower risk of subsequent stroke: a retrospective cohort study of 137 children with sickle cell anemia. Hulbert ML, Scothorn DJ, Panepinto JA, Scott JP, Buchanan GR, Sarnaik S, Fallon R, Chu JY, Wang W, Casella JF, Resar L, Berman B, Adamkiewicz T, Hsu LL, Smith-Whitley K, Mahoney D, Woods G, Watanabe M, DeBaun MR (2006) J Pediatr 149: 710-2 Risk of recurrent stroke in children with sickle cell disease receiving blood transfusion therapy for at least five years after initial stroke. Scothorn DJ, Price C, Schwartz D, Terrill C, Buchanan GR, Shurney W, Sarniak I, Fallon R, Chu JY, Pegelow CH, Wang W, Casella JF, Resar LS, Berman B, Adamkiewicz T, Hsu LL, Ohene-Frempong K, Smith-Whitley K, Mahoney D, Scott JP, Woods GM, Watanabe M, Debaun MR (2002) J Pediatr 140: 348-54 Headache and migraine in children with sickle cell disease are associated with lower hemoglobin and higher pain event rates but not silent cerebral infarction. Dowling MM, Noetzel MJ, Rodeghier MJ, Quinn CT, Hirtz DG, Ichord RN, Kwiatkowski JL, Roach ES, Kirkham FJ, Casella JF, DeBaun MR (2014) J Pediatr 164: 1175-1180.e1 Evolution of sickle cell disease from a life-threatening disease of children to a chronic disease of adults: The last 40 years. Chaturvedi S, DeBaun MR (2016) Am J Hematol 91: 5-14 Health-related quality of life in children with sickle cell anemia: impact of blood transfusion therapy. Beverung LM, Strouse JJ, Hulbert ML, Neville K, Liem RI, Inusa B, Fuh B, King A, Meier ER, Casella J, DeBaun MR, Panepinto JA, SIT trial investigators (2015) Am J Hematol 90: 139-43 Advancement of pediatric blood and marrow transplantation research in North America: priorities of the Pediatric Blood and Marrow Transplant Consortium. Pulsipher MA, Horwitz EM, Haight AE, Kadota R, Chen AR, Frangoul H, Cooper LJ, Jacobsohn DA, Goyal RK, Mitchell D, Nieder ML, Yanik G, Cowan MJ, Soni S, Gardner S, Shenoy S, Taylor D, Cairo M, Schultz KR (2010) Biol Blood Marrow Transplant 16: 1212-21 Complications of midtrimester pregnancy termination: the effect of prior cesarean delivery. Chapman SJ, Crispens M, Owen J, Savage K (1996) Am J Obstet Gynecol 175: 889-92 Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells. Hao J, Daleo MA, Murphy CK, Yu PB, Ho JN, Hu J, Peterson RT, Hatzopoulos AK, Hong CC (2008) PLoS One 3: e2904 Blood loss associated with radical cystectomy: a prospective, randomized study comparing Impact LigaSure vs. stapling device. Thompson IM, Kappa SF, Morgan TM, Barocas DA, Bischoff CJ, Keegan KA, Stratton KL, Clark PE, Resnick MJ, Smith JA, Cookson MS, Chang SS (2014) Urol Oncol 32: 45.e11-5 The relationship of plasma transfusion from female and male donors with outcome after cardiac surgery. Welsby IJ, Troughton M, Phillips-Bute B, Ramsey R, Campbell ML, Bandarenko N, Mathew JP, Stafford-Smith M, Cardiothoracic Anesthesiology Research Endeavors (2010) J Thorac Cardiovasc Surg 140: 1353-60 The impact of heparin concentration and activated clotting time monitoring on blood conservation. A prospective, randomized evaluation in patients undergoing cardiac operation. Despotis GJ, Joist JH, Hogue CW, Alsoufiev A, Kater K, Goodnough LT, Santoro SA, Spitznagel E, Rosenblum M, Lappas DG (1995) J Thorac Cardiovasc Surg 110: 46-54 Mailing of a sickle cell disease educational packet increases blood donors within an African American community. Price CL, Boyd JH, Watkins AR, Fleming F, DeBaun MR (2006) Transfusion 46: 1388-93 Acute lung injury after blood transfusion in mechanically ventilated patients. Gajic O, Rana R, Mendez JL, Rickman OB, Lymp JF, Hubmayr RD, Moore SB (2004) Transfusion 44: 1468-74 Prospective evaluation and clinical utility of on-site monitoring of coagulation in patients undergoing cardiac operation. Despotis GJ, Santoro SA, Spitznagel E, Kater KM, Cox JL, Barnes P, Lappas DG (1994) J Thorac Cardiovasc Surg 107: 271-9 Intraoperative use of low-dose recombinant activated factor VII during thoracic aortic operations. Andersen ND, Bhattacharya SD, Williams JB, Fosbol EL, Lockhart EL, Patel MB, Gaca JG, Welsby IJ, Hughes GC (2012) Ann Thorac Surg 93: 1921-8; discussion 1928-9 Use of aprotinin in extrapleural pneumonectomy: effect on hemostasis and incidence of complications. Bakaeen F, Rice D, Correa AM, Walsh GL, Vaporciyan AA, Putnam JB, Swisher SG, Roth JA, Huh J, Chu D, Smythe WR (2007) Ann Thorac Surg 84: 982-6 Perioperative blood product use: a comparison between HeartWare and HeartMate II devices. Haglund NA, Davis ME, Tricarico NM, Ahmad RM, DiSalvo TG, Keebler ME, Schlendorf KH, Wigger MA, Stulak JM, Maltais S (2014) Ann Thorac Surg 98: 842-9 Hemorrhagic complications of percutaneous radiofrequency ablation for liver tumors. Goto E, Tateishi R, Shiina S, Masuzaki R, Enooku K, Sato T, Ohki T, Kondo Y, Goto T, Yoshida H, Omata M (2010) J Clin Gastroenterol 44: 374-80 Comparison of transfusion requirements between open and robotic-assisted laparoscopic radical prostatectomy. Kordan Y, Barocas DA, Altamar HO, Clark PE, Chang SS, Davis R, Herrell SD, Baumgartner R, Mishra V, Chan RC, Smith JA, Cookson MS (2010) BJU Int 106: 1036-40 The case for and against initiating either hydroxyurea therapy, blood transfusion therapy or hematopoietic stem cell transplant in asymptomatic children with sickle cell disease. Kassim AA, DeBaun MR (2014) Expert Opin Pharmacother 15: 325-36 Analysis of variables affecting wound healing after musculoskeletal sarcoma resections. Chmell MJ, Schwartz HS (1996) J Surg Oncol 61: 185-9
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