Evidence that histamine is the causative toxin of scombroid-fish poisoning. Morrow JD, Margolies GR, Rowland J, Roberts LJ (1991) N Engl J Med 324: 716-20 Blockade of the flush associated with metastatic gastric carcinoid by combined histamine H1 and H2 receptor antagonists. Evidence for an important role of H2 receptors in human vasculature. Roberts LJ, Marney SR, Oates JA (1979) N Engl J Med 300: 236-8 Increased production of prostaglandin D2 in patients with systemic mastocytosis. Roberts LJ, Sweetman BJ, Lewis RA, Austen KF, Oates JA (1980) N Engl J Med 303: 1400-4 Increased adventitial mast cells in a patient with coronary spasm. Forman MB, Oates JA, Robertson D, Robertson RM, Roberts LJ, Virmani R (1985) N Engl J Med 313: 1138-41 Histamine inhibition of neutrophil lysosomal enzyme release: an H2 histamine receptor response. Busse WW, Sosman J (1976) Science 194: 737-8 The International Serious Adverse Events Consortium (iSAEC) phenotype standardization project for drug-induced torsades de pointes. Behr ER, January C, Schulze-Bahr E, Grace AA, Kääb S, Fiszman M, Gathers S, Buckman S, Youssef A, Pirmohamed M, Roden D (2013) Eur Heart J 34: 1958-63 Histamine release from a gastric carcinoid: provocation by pentagastrin and inhibition by somatostatin. Roberts LJ, Bloomgarden ZT, Marney SR, Rabin D, Oates JA (1983) Gastroenterology 84: 272-5 Risk of peptic ulcer hospitalizations in users of NSAIDs with gastroprotective cotherapy versus coxibs. Ray WA, Chung CP, Stein CM, Smalley WE, Hall K, Arbogast PG, Griffin MR (2007) Gastroenterology 133: 790-8 Decreased H2 histamine response of granulocytes of asthmatic patients. Busse WW, Sosman J (1977) J Clin Invest 59: 1080-7 Intervention with epinephrine in hypotension associated with mastocytosis. Turk J, Oates JA, Roberts LJ (1983) J Allergy Clin Immunol 71: 189-92 Recurrent syncope due to systemic mastocytosis. Roberts LJ (1984) Hypertension 6: 285-94 Hyperadrenergic postural tachycardia syndrome in mast cell activation disorders. Shibao C, Arzubiaga C, Roberts LJ, Raj S, Black B, Harris P, Biaggioni I (2005) Hypertension 45: 385-90 Intestinal drug transporter expression and the impact of grapefruit juice in humans. Glaeser H, Bailey DG, Dresser GK, Gregor JC, Schwarz UI, McGrath JS, Jolicoeur E, Lee W, Leake BF, Tirona RG, Kim RB (2007) Clin Pharmacol Ther 81: 362-70 Are herbal products dietary supplements or drugs? An important question for public safety. Stein CM (2002) Clin Pharmacol Ther 71: 411-3 Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. Bailey DG, Dresser GK, Leake BF, Kim RB (2007) Clin Pharmacol Ther 81: 495-502 Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. Dresser GK, Bailey DG, Leake BF, Schwarz UI, Dawson PA, Freeman DJ, Kim RB (2002) Clin Pharmacol Ther 71: 11-20 Hazards in operative management of patients with systemic mastocytosis. Scott HW, Parris WC, Sandidge PC, Oates JA, Roberts LJ (1983) Ann Surg 197: 507-14 Biochemical diagnosis of systemic mast cell disorders. Roberts LJ, Oates JA (1991) J Invest Dermatol 96: 19S-24S; discussion 24S-25S; 60S-65S Identification of skin as a major site of prostaglandin D2 release following oral administration of niacin in humans. Morrow JD, Awad JA, Oates JA, Roberts LJ (1992) J Invest Dermatol 98: 812-5 Improved diagnosis of mastocytosis by measurement of the major urinary metabolite of prostaglandin D2. Morrow JD, Guzzo C, Lazarus G, Oates JA, Roberts LJ (1995) J Invest Dermatol 104: 937-40 Histamine directly and synergistically with lipopolysaccharide stimulates cyclooxygenase-2 expression and prostaglandin I(2) and E(2) production in human coronary artery endothelial cells. Tan X, Essengue S, Talreja J, Reese J, Stechschulte DJ, Dileepan KN (2007) J Immunol 179: 7899-906 Effects of indomethacin on cyclic nucleotide levels and histamine release from rat serosal mast cells. Lewis RA, Holgate ST, Roberts LJ, Maguire JF, Oates JA, Austen KF (1979) J Immunol 123: 1663-8 Cimetidine-associated patent ductus arteriosus is mediated via a cytochrome P450 mechanism independent of H2 receptor antagonism. Cotton RB, Shah LP, Poole SD, Ehinger NJ, Brown N, Shelton EL, Slaughter JC, Baldwin HS, Paria BC, Reese J (2013) J Mol Cell Cardiol 59: 86-94 Urticaria pigmentosa. Systemic evaluation and successful treatment with topical steroids. Guzzo C, Lavker R, Roberts LJ, Fox K, Schechter N, Lazarus G (1991) Arch Dermatol 127: 191-6 Functional selectivity induced by mGlu₄ receptor positive allosteric modulation and concomitant activation of Gq coupled receptors. Yin S, Zamorano R, Conn PJ, Niswender CM (2013) Neuropharmacology 66: 122-32
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.