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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Warfarin are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Warfarin.
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- Clinical problem-solving. High time for action.
Kallianpur AR, Poehling KA, Dittus RS
(2001) N Engl J Med 344: 48-51 - Genetic determinants of response to warfarin during initial anticoagulation.
Schwarz UI, Ritchie MD, Bradford Y, Li C, Dudek SM, Frye-Anderson A, Kim RB, Roden DM, Stein CM
(2008) N Engl J Med 358: 999-1008 - Estimation of the warfarin dose with clinical and pharmacogenetic data.
International Warfarin Pharmacogenetics Consortium, Klein TE, Altman RB, Eriksson N, Gage BF, Kimmel SE, Lee MT, Limdi NA, Page D, Roden DM, Wagner MJ, Caldwell MD, Johnson JA
(2009) N Engl J Med 360: 753-64 - Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.
Perera MA, Cavallari LH, Limdi NA, Gamazon ER, Konkashbaev A, Daneshjou R, Pluzhnikov A, Crawford DC, Wang J, Liu N, Tatonetti N, Bourgeois S, Takahashi H, Bradford Y, Burkley BM, Desnick RJ, Halperin JL, Khalifa SI, Langaee TY, Lubitz SA, Nutescu EA, Oetjens M, Shahin MH, Patel SR, Sagreiya H, Tector M, Weck KE, Rieder MJ, Scott SA, Wu AH, Burmester JK, Wadelius M, Deloukas P, Wagner MJ, Mushiroda T, Kubo M, Roden DM, Cox NJ, Altman RB, Klein TE, Nakamura Y, Johnson JA
(2013) Lancet 382: 790-6 - A risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the community: the Framingham Heart Study.
Wang TJ, Massaro JM, Levy D, Vasan RS, Wolf PA, D'Agostino RB, Larson MG, Kannel WB, Benjamin EJ
(2003) JAMA 290: 1049-56 - Applied pharmacogenomics in cardiovascular medicine.
Weeke P, Roden DM
(2014) Annu Rev Med 65: 81-94 - Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy.
Gong IY, Tirona RG, Schwarz UI, Crown N, Dresser GK, Larue S, Langlois N, Lazo-Langner A, Zou G, Roden DM, Stein CM, Rodger M, Carrier M, Forgie M, Wells PS, Kim RB
(2011) Blood 118: 3163-71 - A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.
Cooper GM, Johnson JA, Langaee TY, Feng H, Stanaway IB, Schwarz UI, Ritchie MD, Stein CM, Roden DM, Smith JD, Veenstra DL, Rettie AE, Rieder MJ
(2008) Blood 112: 1022-7 - Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans.
Daneshjou R, Gamazon ER, Burkley B, Cavallari LH, Johnson JA, Klein TE, Limdi N, Hillenmeyer S, Percha B, Karczewski KJ, Langaee T, Patel SR, Bustamante CD, Altman RB, Perera MA
(2014) Blood 124: 2298-305 - Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapy.
Li C, Schwarz UI, Ritchie MD, Roden DM, Stein CM, Kurnik D
(2009) Blood 113: 3925-30 - Warfarin use associates with increased risk for stroke in hemodialysis patients with atrial fibrillation.
Chan KE, Lazarus JM, Thadhani R, Hakim RM
(2009) J Am Soc Nephrol 20: 2223-33 - Anticoagulant and antiplatelet usage associates with mortality among hemodialysis patients.
Chan KE, Lazarus JM, Thadhani R, Hakim RM
(2009) J Am Soc Nephrol 20: 872-81 - Genetic determinants of dose and clinical outcomes in patients receiving oral anticoagulants.
Schwarz UI, Stein CM
(2006) Clin Pharmacol Ther 80: 7-12 - The missing association: sequencing-based discovery of novel SNPs in VKORC1 and CYP2C9 that affect warfarin dose in African Americans.
Perera MA, Gamazon E, Cavallari LH, Patel SR, Poindexter S, Kittles RA, Nicolae D, Cox NJ
(2011) Clin Pharmacol Ther 89: 408-15 - Pharmacogenetic Implementation Lessons From the "Real World".
Roden DM
(2017) Clin Pharmacol Ther 102: 25-27 - The effect of anticoagulants on cancer risk and survival: systematic review.
Tagalakis V, Blostein M, Robinson-Cohen C, Kahn SR
(2007) Cancer Treat Rev 33: 358-68 - A prognostic model based on readily available clinical data enriched a pre-emptive pharmacogenetic testing program.
Schildcrout JS, Shi Y, Danciu I, Bowton E, Field JR, Pulley JM, Basford MA, Gregg W, Cowan JD, Harrell FE, Roden DM, Peterson JF, Denny JC
(2016) J Clin Epidemiol 72: 107-15 - Ethnicity-specific pharmacogenetics: the case of warfarin in African Americans.
Hernandez W, Gamazon ER, Aquino-Michaels K, Patel S, O'Brien TJ, Harralson AF, Kittles RA, Barbour A, Tuck M, McIntosh SD, Douglas JN, Nicolae D, Cavallari LH, Perera MA
(2014) Pharmacogenomics J 14: 223-8 - The impact of age and CYP2C9 and VKORC1 variants on stable warfarin dose in the paediatric population.
Vear SI, Ayers GD, Van Driest SL, Sidonio RF, Stein CM, Ho RH
(2014) Br J Haematol 165: 832-5 - Comparative studies on the catalytic roles of cytochrome P450 2C9 and its Cys- and Leu-variants in the oxidation of warfarin, flurbiprofen, and diclofenac by human liver microsomes.
Yamazaki H, Inoue K, Chiba K, Ozawa N, Kawai T, Suzuki Y, Goldstein JA, Guengerich FP, Shimada T
(1998) Biochem Pharmacol 56: 243-51 - Prevalence and implications of preinjury warfarin use: an analysis of the National Trauma Databank.
Dossett LA, Riesel JN, Griffin MR, Cotton BA
(2011) Arch Surg 146: 565-70 - Antithrombotic treatment in neonatal cerebral sinovenous thrombosis: results of the International Pediatric Stroke Study.
Jordan LC, Rafay MF, Smith SE, Askalan R, Zamel KM, deVeber G, Ashwal S, International Pediatric Stroke Study Group
(2010) J Pediatr 156: 704-10, 710.e1-710.e2 - Genotype and risk of major bleeding during warfarin treatment.
Kawai VK, Cunningham A, Vear SI, Van Driest SL, Oginni A, Xu H, Jiang M, Li C, Denny JC, Shaffer C, Bowton E, Gage BF, Ray WA, Roden DM, Stein CM
(2014) Pharmacogenomics 15: 1973-83 - Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record.
Ramirez AH, Shi Y, Schildcrout JS, Delaney JT, Xu H, Oetjens MT, Zuvich RL, Basford MA, Bowton E, Jiang M, Speltz P, Zink R, Cowan J, Pulley JM, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC
(2012) Pharmacogenomics 13: 407-18 - Clinical and genetic determinants of warfarin pharmacokinetics and pharmacodynamics during treatment initiation.
Gong IY, Schwarz UI, Crown N, Dresser GK, Lazo-Langner A, Zou G, Roden DM, Stein CM, Rodger M, Wells PS, Kim RB, Tirona RG
(2011) PLoS One 6: e27808 - Genetic determinants of variability in warfarin response after the dose-titration phase.
Iwuchukwu OF, Ramirez AH, Shi Y, Bowton EA, Kawai VK, Schildcrout JS, Roden DM, Denny JC, Stein CM
(2016) Pharmacogenet Genomics 26: 510-516 - Facilitating pharmacogenetic studies using electronic health records and natural-language processing: a case study of warfarin.
Xu H, Jiang M, Oetjens M, Bowton EA, Ramirez AH, Jeff JM, Basford MA, Pulley JM, Cowan JD, Wang X, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC
(2011) J Am Med Inform Assoc 18: 387-91 - Multiple episodes of thrombosis with biventricular support devices with inadequate anticoagulation and evidence of accelerated intravascular coagulation.
Despotis GJ, Levine V, Joist H, Santoro SA, Mendeloff E
(1997) J Thorac Cardiovasc Surg 113: 419-22 - Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.
Yamazaki H, Gillam EM, Dong MS, Johnson WW, Guengerich FP, Shimada T
(1997) Arch Biochem Biophys 342: 329-37 - Cardiovascular pharmacogenomics: current status and future directions.
Roden DM
(2016) J Hum Genet 61: 79-85 - Warfarin pharmacogenomics in children.
Vear SI, Stein CM, Ho RH
(2013) Pediatr Blood Cancer 60: 1402-7 - Pulmonary embolism after total joint arthroplasty: cost and effectiveness of four treatment modalities.
Raphael IJ, McKenzie JC, Zmistowski B, Brown DB, Parvizi J, Austin MS
(2014) J Arthroplasty 29: 933-7 - Intracardiac thrombosis complicating antiphospholipid antibody syndrome.
Lim E, Wicks I, Roberts LJ
(2004) Intern Med J 34: 135-7 - Vitamin K intake, body mass index and warfarin maintenance dose.
Kabagambe EK, Beasley TM, Limdi NA
(2013) Cardiology 126: 214-8
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