Keyword Connections

•  Ryan Stark

Resources

• No matching connections

Communities

• No matching connections

Publications

• Cardiomyocyte-restricted overexpression of endothelial nitric oxide synthase (NOS3) attenuates beta-adrenergic stimulation and reinforces vagal inhibition of cardiac contraction.
  Massion PB, Dessy C, Desjardins F, Pelat M, Havaux X, Belge C, Moulin P, Guiot Y, Feron O, Janssens S, Balligand JL
  (2004) Circulation 110: 2666-72
• Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress-specific manner.
  Woo KV, Qu X, Babaev VR, Linton MF, Guzman RJ, Fazio S, Baldwin HS
  (2011) J Clin Invest 121: 1624-35
• Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension.
  Landmesser U, Dikalov S, Price SR, McCann L, Fukai T, Holland SM, Mitch WE, Harrison DG
  (2003) J Clin Invest 111: 1201-9
• Impaired liver regeneration in mice lacking glycine N-methyltransferase.
  Varela-Rey M, Fernández-Ramos D, Martínez-López N, Embade N, Gómez-Santos L, Beraza N, Vázquez-Chantada M, Rodríguez J, Luka Z, Wagner C, Lu SC, Martínez-Chantar ML, Mato JM
  (2009) Hepatology 50: 443-52
• Induction of vascular insulin resistance and endothelin-1 expression and acceleration of atherosclerosis by the overexpression of protein kinase C-β isoform in the endothelium.
  Li Q, Park K, Li C, Rask-Madsen C, Mima A, Qi W, Mizutani K, Huang P, King GL
  (2013) Circ Res 113: 418-27
• GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide.
  Li L, Rezvan A, Salerno JC, Husain A, Kwon K, Jo H, Harrison DG, Chen W
  (2010) Circ Res 106: 328-36
• cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism.
  Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA
  (2005) Circ Res 96: 100-9
• Angiotensinergic stimulation of vascular endothelium in mice causes hypotension, bradycardia, and attenuated angiotensin response.
  Ramchandran R, Takezako T, Saad Y, Stull L, Fink B, Yamada H, Dikalov S, Harrison DG, Moravec C, Karnik SS
  (2006) Proc Natl Acad Sci U S A 103: 19087-92
• Mouse models of diabetic nephropathy.
  Brosius FC, Alpers CE, Bottinger EP, Breyer MD, Coffman TM, Gurley SB, Harris RC, Kakoki M, Kretzler M, Leiter EH, Levi M, McIndoe RA, Sharma K, Smithies O, Susztak K, Takahashi N, Takahashi T, Animal Models of Diabetic Complications Consortium
  (2009) J Am Soc Nephrol 20: 2503-12
• Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice.
  Zhao HJ, Wang S, Cheng H, Zhang MZ, Takahashi T, Fogo AB, Breyer MD, Harris RC
  (2006) J Am Soc Nephrol 17: 2664-9
• eNOS deficiency predisposes podocytes to injury in diabetes.
  Yuen DA, Stead BE, Zhang Y, White KE, Kabir MG, Thai K, Advani SL, Connelly KA, Takano T, Zhu L, Cox AJ, Kelly DJ, Gibson IW, Takahashi T, Harris RC, Advani A
  (2012) J Am Soc Nephrol 23: 1810-23
• Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice.
  Cheng H, Wang H, Fan X, Paueksakon P, Harris RC
  (2012) Kidney Int 82: 1176-83
• Low nitric oxide bioavailability upregulates renal heparin binding EGF-like growth factor expression.
  Miyazawa T, Zeng F, Wang S, Fan X, Cheng H, Yang H, Bian A, Fogo AB, Harris RC
  (2013) Kidney Int 84: 1176-88
• Imaging mass spectrometry reveals direct albumin fragmentation within the diabetic kidney.
  Grove KJ, Lareau NM, Voziyan PA, Zeng F, Harris RC, Hudson BG, Caprioli RM
  (2018) Kidney Int 94: 292-302
• Inhibition of Epidermal Growth Factor Receptor Activation Is Associated With Improved Diabetic Nephropathy and Insulin Resistance in Type 2 Diabetes.
  Li Z, Li Y, Overstreet JM, Chung S, Niu A, Fan X, Wang S, Wang Y, Zhang MZ, Harris RC
  (2018) Diabetes 67: 1847-1857
• Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension.
  Cook S, Hugli O, Egli M, Ménard B, Thalmann S, Sartori C, Perrin C, Nicod P, Thorens B, Vollenweider P, Scherrer U, Burcelin R
  (2004) Diabetes 53: 2067-72
• Hypohalous acids contribute to renal extracellular matrix damage in experimental diabetes.
  Brown KL, Darris C, Rose KL, Sanchez OA, Madu H, Avance J, Brooks N, Zhang MZ, Fogo A, Harris R, Hudson BG, Voziyan P
  (2015) Diabetes 64: 2242-53
• Reactive oxygen species-reducing strategies improve pulmonary arterial responses to nitric oxide in piglets with chronic hypoxia-induced pulmonary hypertension.
  Fike CD, Dikalova A, Slaughter JC, Kaplowitz MR, Zhang Y, Aschner JL
  (2013) Antioxid Redox Signal 18: 1727-38
• Contribution of endothelial nitric oxide to blood pressure in humans.
  Gamboa A, Shibao C, Diedrich A, Choi L, Pohar B, Jordan J, Paranjape S, Farley G, Biaggioni I
  (2007) Hypertension 49: 170-7
• Role of extracellular superoxide dismutase in hypertension.
  Gongora MC, Qin Z, Laude K, Kim HW, McCann L, Folz JR, Dikalov S, Fukai T, Harrison DG
  (2006) Hypertension 48: 473-81
• Endothelial NO synthase polymorphisms and postural tachycardia syndrome.
  Garland EM, Winker R, Williams SM, Jiang L, Stanton K, Byrne DW, Biaggioni I, Cascorbi I, Phillips JA, Harris PA, Rüdiger H, Robertson D
  (2005) Hypertension 46: 1103-10
• Selective β2-adrenoreceptor stimulation attenuates myocardial cell death and preserves cardiac function after ischemia-reperfusion injury.
  Bhushan S, Kondo K, Predmore BL, Zlatopolsky M, King AL, Pearce C, Huang H, Tao YX, Condit ME, Lefer DJ
  (2012) Arterioscler Thromb Vasc Biol 32: 1865-74
• Endothelial nitric oxide synthase modulates Toll-like receptor 4-mediated IL-6 production and permeability via nitric oxide-independent signaling.
  Stark RJ, Koch SR, Choi H, Mace EH, Dikalov SI, Sherwood ER, Lamb FS
  (2018) FASEB J 32: 945-956
• Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells.
  Jones W, Li X, Qu ZC, Perriott L, Whitesell RR, May JM
  (2002) Free Radic Biol Med 33: 83-93
• Cross talk between mitochondria and NADPH oxidases.
  Dikalov S
  (2011) Free Radic Biol Med 51: 1289-301
• Coordinate regulation of L-arginine uptake and nitric oxide synthase activity in cultured endothelial cells.
  Hardy TA, May JM
  (2002) Free Radic Biol Med 32: 122-31
• How does ascorbic acid prevent endothelial dysfunction?
  May JM
  (2000) Free Radic Biol Med 28: 1421-9
• Toll-like receptor 3-mediated inflammation by p38 is enhanced by endothelial nitric oxide synthase knockdown.
  Koch SR, Choi H, Mace EH, Stark RJ
  (2019) Cell Commun Signal 17: 33
• Arginase II inhibition prevents nitrate tolerance.
  Khong SM, Andrews KL, Huynh NN, Venardos K, Aprico A, Michell DL, Zarei M, Moe KT, Dusting GJ, Kaye DM, Chin-Dusting JP
  (2012) Br J Pharmacol 166: 2015-23
• Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase.
  Kuzkaya N, Weissmann N, Harrison DG, Dikalov S
  (2003) J Biol Chem 278: 22546-54
• Geldanamycin leads to superoxide formation by enzymatic and non-enzymatic redox cycling. Implications for studies of Hsp90 and endothelial cell nitric-oxide synthase.
  Dikalov S, Landmesser U, Harrison DG
  (2002) J Biol Chem 277: 25480-5
• Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: implications for uncoupling endothelial nitric oxide synthase.
  Kuzkaya N, Weissmann N, Harrison DG, Dikalov S
  (2005) Biochem Pharmacol 70: 343-54
• Antioxidant effects of dihydrocaffeic acid in human EA.hy926 endothelial cells.
  Huang J, de Paulis T, May JM
  (2004) J Nutr Biochem 15: 722-9
• Deficiency of endothelial nitric-oxide synthase confers susceptibility to diabetic nephropathy in nephropathy-resistant inbred mice.
  Kanetsuna Y, Takahashi K, Nagata M, Gannon MA, Breyer MD, Harris RC, Takahashi T
  (2007) Am J Pathol 170: 1473-84
• Endothelial nitric-oxide synthase reveals a new face in G protein signaling.
  Bilodeau ML, Hamm HE
  (2006) Mol Pharmacol 69: 677-9
• Lung extracellular superoxide dismutase overexpression lessens bleomycin-induced pulmonary hypertension and vascular remodeling.
  Van Rheen Z, Fattman C, Domarski S, Majka S, Klemm D, Stenmark KR, Nozik-Grayck E
  (2011) Am J Respir Cell Mol Biol 44: 500-8
• Pulmonary and systemic nitric oxide metabolites in a baboon model of neonatal chronic lung disease.
  Munson DA, Grubb PH, Kerecman JD, McCurnin DC, Yoder BA, Hazen SL, Shaul PW, Ischiropoulos H
  (2005) Am J Respir Cell Mol Biol 33: 582-8
• Effects of Advancing Gestation and Non-Caucasian Race on Ductus Arteriosus Gene Expression.
  Waleh N, Barrette AM, Dagle JM, Momany A, Jin C, Hills NK, Shelton EL, Reese J, Clyman RI
  (2015) J Pediatr 167: 1033-41.e2
• Sodium-coupled neutral amino acid transporter 1 (SNAT1) modulates L-citrulline transport and nitric oxide (NO) signaling in piglet pulmonary arterial endothelial cells.
  Dikalova A, Fagiana A, Aschner JL, Aschner M, Summar M, Fike CD
  (2014) PLoS One 9: e85730
• Molecular beacons can assess changes in expression and 3'-polyadenylation of human eNOS mRNA.
  Jones R, Baker MB, Weber M, Harrison DG, Bao G, Searles CD
  (2009) Am J Physiol Cell Physiol 296: C498-504