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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Mice, Obese are shown below. Double-click or tap a node for more information.
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- Allosteric activators of glucokinase: potential role in diabetes therapy.
Grimsby J, Sarabu R, Corbett WL, Haynes NE, Bizzarro FT, Coffey JW, Guertin KR, Hilliard DW, Kester RF, Mahaney PE, Marcus L, Qi L, Spence CL, Tengi J, Magnuson MA, Chu CA, Dvorozniak MT, Matschinsky FM, Grippo JF
(2003) Science 301: 370-3 - Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents.
Scarlett JM, Rojas JM, Matsen ME, Kaiyala KJ, Stefanovski D, Bergman RN, Nguyen HT, Dorfman MD, Lantier L, Wasserman DH, Mirzadeh Z, Unterman TG, Morton GJ, Schwartz MW
(2016) Nat Med 22: 800-6 - S-adenosylmethionine levels regulate the schwann cell DNA methylome.
Varela-Rey M, Iruarrizaga-Lejarreta M, Lozano JJ, Aransay AM, Fernandez AF, Lavin JL, Mósen-Ansorena D, Berdasco M, Turmaine M, Luka Z, Wagner C, Lu SC, Esteller M, Mirsky R, Jessen KR, Fraga MF, Martínez-Chantar ML, Mato JM, Woodhoo A
(2014) Neuron 81: 1024-1039 - FGF19 action in the brain induces insulin-independent glucose lowering.
Morton GJ, Matsen ME, Bracy DP, Meek TH, Nguyen HT, Stefanovski D, Bergman RN, Wasserman DH, Schwartz MW
(2013) J Clin Invest 123: 4799-808 - Cyclooxygenase-2 in adipose tissue macrophages limits adipose tissue dysfunction in obese mice.
Pan Y, Cao S, Tang J, Arroyo JP, Terker AS, Wang Y, Niu A, Fan X, Wang S, Zhang Y, Jiang M, Wasserman DH, Zhang MZ, Harris RC
(2022) J Clin Invest 132: - Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet.
Li S, Sun Y, Liang CP, Thorp EB, Han S, Jehle AW, Saraswathi V, Pridgen B, Kanter JE, Li R, Welch CL, Hasty AH, Bornfeldt KE, Breslow JL, Tabas I, Tall AR
(2009) Circ Res 105: 1072-82 - Molecular genetic analysis of diabetes in mice.
Gannon M
(2001) Trends Genet 17: S23-8 - Serum leptin level is a regulator of bone mass.
Elefteriou F, Takeda S, Ebihara K, Magre J, Patano N, Kim CA, Ogawa Y, Liu X, Ware SM, Craigen WJ, Robert JJ, Vinson C, Nakao K, Capeau J, Karsenty G
(2004) Proc Natl Acad Sci U S A 101: 3258-63 - Pyruvate induces torpor in obese mice.
Soto M, Orliaguet L, Reyzer ML, Manier ML, Caprioli RM, Kahn CR
(2018) Proc Natl Acad Sci U S A 115: 810-815 - Identification of microsatellite markers near the human ob gene and linkage studies in NIDDM-affected sib pairs.
Stirling B, Cox NJ, Bell GI, Hanis CL, Spielman RS, Concannon P
(1995) Diabetes 44: 999-1001 - Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice.
Kang L, Mokshagundam S, Reuter B, Lark DS, Sneddon CC, Hennayake C, Williams AS, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH
(2016) Diabetes 65: 1590-600 - Pancreatic islet vasculature adapts to insulin resistance through dilation and not angiogenesis.
Dai C, Brissova M, Reinert RB, Nyman L, Liu EH, Thompson C, Shostak A, Shiota M, Takahashi T, Powers AC
(2013) Diabetes 62: 4144-53 - Differentiating short- and long-term effects of diet in the obese mouse using (1) H-nuclear magnetic resonance metabolomics.
Duggan GE, Hittel DS, Hughey CC, Weljie A, Vogel HJ, Shearer J
(2011) Diabetes Obes Metab 13: 859-62 - A novel experimental strategy to assess the metabolic effects of selective activation of a G(q)-coupled receptor in hepatocytes in vivo.
Li JH, Jain S, McMillin SM, Cui Y, Gautam D, Sakamoto W, Lu H, Jou W, McGuinness OP, Gavrilova O, Wess J
(2013) Endocrinology 154: 3539-51 - Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity.
Berglund ED, Li CY, Bina HA, Lynes SE, Michael MD, Shanafelt AB, Kharitonenkov A, Wasserman DH
(2009) Endocrinology 150: 4084-93 - Neuropeptide W: an anorectic peptide regulated by leptin and metabolic state.
Date Y, Mondal MS, Kageyama H, Ghamari-Langroudi M, Takenoya F, Yamaguchi H, Shimomura Y, Mori M, Murakami N, Shioda S, Cone RD, Nakazato M
(2010) Endocrinology 151: 2200-10 - Interferon-stimulated gene ISG12b1 inhibits adipogenic differentiation and mitochondrial biogenesis in 3T3-L1 cells.
Li B, Shin J, Lee K
(2009) Endocrinology 150: 1217-24 - Obesity causes very low density lipoprotein clearance defects in low-density lipoprotein receptor-deficient mice.
Coenen KR, Gruen ML, Hasty AH
(2007) J Nutr Biochem 18: 727-35 - Loss of CCR5 results in glucose intolerance in diet-induced obese mice.
Kennedy A, Webb CD, Hill AA, Gruen ML, Jackson LG, Hasty AH
(2013) Am J Physiol Endocrinol Metab 305: E897-906 - Automated quantification of pancreatic β-cell mass.
Golson ML, Bush WS, Brissova M
(2014) Am J Physiol Endocrinol Metab 306: E1460-7 - Carbenoxolone treatment attenuates symptoms of metabolic syndrome and atherogenesis in obese, hyperlipidemic mice.
Nuotio-Antar AM, Hachey DL, Hasty AH
(2007) Am J Physiol Endocrinol Metab 293: E1517-28 - Ablation of ghrelin receptor in leptin-deficient ob/ob mice has paradoxical effects on glucose homeostasis when compared with ablation of ghrelin in ob/ob mice.
Ma X, Lin Y, Lin L, Qin G, Pereira FA, Haymond MW, Butte NF, Sun Y
(2012) Am J Physiol Endocrinol Metab 303: E422-31 - Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice.
Depner CM, Torres-Gonzalez M, Tripathy S, Milne G, Jump DB
(2012) J Nutr 142: 1495-503 - Transendothelial Insulin Transport is Impaired in Skeletal Muscle Capillaries of Obese Male Mice.
Williams IM, McClatchey PM, Bracy DP, Bonner JS, Valenzuela FA, Wasserman DH
(2020) Obesity (Silver Spring) 28: 303-314 - CD8 T cells regulate liver injury in obesity-related nonalcoholic fatty liver disease.
Breuer DA, Pacheco MC, Washington MK, Montgomery SA, Hasty AH, Kennedy AJ
(2020) Am J Physiol Gastrointest Liver Physiol 318: G211-G224 - Anti-obesity effects of KR-66195, a synthetic DPP-IV inhibitor, in diet-induced obese mice and obese-diabetic ob/ob mice.
Lee EY, Kim YW, Oh H, Choi CS, Ahn JH, Lee BW, Kang ES, Cha BS, Lee HC
(2014) Metabolism 63: 793-9 - [Bone mass regulation by leptin: a hypothalamic control of bone formation].
Elefteriou F, Karsenty G
(2004) Pathol Biol (Paris) 52: 148-53 - Expression and shifting subcellular localization of the transcription factor, Foxd3, in embryonic and adult pancreas.
Perera HK, Caldwell ME, Hayes-Patterson D, Teng L, Peshavaria M, Jetton TL, Labosky PA
(2006) Gene Expr Patterns 6: 971-7
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