CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer. Wang D, Wang H, Brown J, Daikoku T, Ning W, Shi Q, Richmond A, Strieter R, Dey SK, DuBois RN (2006) J Exp Med 203: 941-51 Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion. Marazioti A, Lilis I, Vreka M, Apostolopoulou H, Kalogeropoulou A, Giopanou I, Giotopoulou GA, Krontira AC, Iliopoulou M, Kanellakis NI, Agalioti T, Giannou AD, Jones-Paris C, Iwakura Y, Kardamakis D, Blackwell TS, Taraviras S, Spella M, Stathopoulos GT (2018) Nat Commun 9: 672 Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulin. Richmond A, Balentien E, Thomas HG, Flaggs G, Barton DE, Spiess J, Bordoni R, Francke U, Derynck R (1988) EMBO J 7: 2025-33 Constitutive IkappaB kinase activity correlates with nuclear factor-kappaB activation in human melanoma cells. Yang J, Richmond A (2001) Cancer Res 61: 4901-9 Elevated constitutive IkappaB kinase activity and IkappaB-alpha phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GRO-alpha transcription. Devalaraja MN, Wang DZ, Ballard DW, Richmond A (1999) Cancer Res 59: 1372-7 HMGI(Y) and Sp1 in addition to NF-kappa B regulate transcription of the MGSA/GRO alpha gene. Wood LD, Farmer AA, Richmond A (1995) Nucleic Acids Res 23: 4210-9 Nucleotide sequence of the human melanoma growth stimulatory activity (MGSA) gene. Baker NE, Kucera G, Richmond A (1990) Nucleic Acids Res 18: 6453 Effects of MGSA/GRO alpha on melanocyte transformation. Balentien E, Mufson BE, Shattuck RL, Derynck R, Richmond A (1991) Oncogene 6: 1115-24 MGSA/GRO-mediated melanocyte transformation involves induction of Ras expression. Wang D, Yang W, Du J, Devalaraja MN, Liang P, Matsumoto K, Tsubakimoto K, Endo T, Richmond A (2000) Oncogene 19: 4647-59 Differential regulation of CXC ligand 1 transcription in melanoma cell lines by poly(ADP-ribose) polymerase-1. Amiri KI, Ha HC, Smulson ME, Richmond A (2006) Oncogene 25: 7714-22 Enhanced tumor-forming capacity for immortalized melanocytes expressing melanoma growth stimulatory activity/growth-regulated cytokine beta and gamma proteins. Owen JD, Strieter R, Burdick M, Haghnegahdar H, Nanney L, Shattuck-Brandt R, Richmond A (1997) Int J Cancer 73: 94-103 Chemokine modulation of the tumor microenvironment. Richmond A (2010) Pigment Cell Melanoma Res 23: 312-3 IL-17A and TNF-α exert synergistic effects on expression of CXCL5 by alveolar type II cells in vivo and in vitro. Liu Y, Mei J, Gonzales L, Yang G, Dai N, Wang P, Zhang P, Favara M, Malcolm KC, Guttentag S, Worthen GS (2011) J Immunol 186: 3197-205 The melanoma growth stimulatory activity receptor consists of two proteins. Ligand binding results in enhanced tyrosine phosphorylation. Cheng QC, Han JH, Thomas HG, Balentien E, Richmond A (1992) J Immunol 148: 451-6 Downregulation of JE and KC genes by glucocorticoids does not prevent the G0----G1 transition in BALB/3T3 cells. Rameh LE, Armelin MC (1992) Mol Cell Biol 12: 4612-21 MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells. Shattuck RL, Wood LD, Jaffe GJ, Richmond A (1994) Mol Cell Biol 14: 791-802 Melanoma growth stimulatory activity enhances the phosphorylation of the class II interleukin-8 receptor in non-hematopoietic cells. Mueller SG, Schraw WP, Richmond A (1994) J Biol Chem 269: 1973-80 Ligand-induced desensitization of the human CXC chemokine receptor-2 is modulated by multiple serine residues in the carboxyl-terminal domain of the receptor. Mueller SG, White JR, Schraw WP, Lam V, Richmond A (1997) J Biol Chem 272: 8207-14 Role of clathrin-mediated endocytosis in CXCR2 sequestration, resensitization, and signal transduction. Yang W, Wang D, Richmond A (1999) J Biol Chem 274: 11328-33 A role for poly(ADP-ribose) polymerase in the transcriptional regulation of the melanoma growth stimulatory activity (CXCL1) gene expression. Nirodi C, NagDas S, Gygi SP, Olson G, Aebersold R, Richmond A (2001) J Biol Chem 276: 9366-74 Nuclear factor-kappa B activation by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein involves the MEKK1/p38 mitogen-activated protein kinase pathway. Wang D, Richmond A (2001) J Biol Chem 276: 3650-9 Constitutive and cytokine-induced expression of the melanoma growth stimulatory activity/GRO alpha gene requires both NF-kappa B and novel constitutive factors. Wood LD, Richmond A (1995) J Biol Chem 270: 30619-26 Activation of protein kinase C enhances the phosphorylation of the type B interleukin-8 receptor and stimulates its degradation in non-hematopoietic cells. Mueller SG, Schraw WP, Richmond A (1995) J Biol Chem 270: 10439-48 Rab11-family interacting protein 2 and myosin Vb are required for CXCR2 recycling and receptor-mediated chemotaxis. Fan GH, Lapierre LA, Goldenring JR, Sai J, Richmond A (2004) Mol Biol Cell 15: 2456-69 Mechanism and biological significance of constitutive expression of MGSA/GRO chemokines in malignant melanoma tumor progression. Luan J, Shattuck-Brandt R, Haghnegahdar H, Owen JD, Strieter R, Burdick M, Nirodi C, Beauchamp D, Johnson KN, Richmond A (1997) J Leukoc Biol 62: 588-97 The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes. Hernandez A, Bohannon JK, Luan L, Fensterheim BA, Guo Y, Patil NK, McAdams C, Wang J, Sherwood ER (2016) J Leukoc Biol 100: 1311-1322 Role of CXCL1 in tumorigenesis of melanoma. Dhawan P, Richmond A (2002) J Leukoc Biol 72: 9-18 The tumorigenic and angiogenic effects of MGSA/GRO proteins in melanoma. Haghnegahdar H, Du J, Wang D, Strieter RM, Burdick MD, Nanney LB, Cardwell N, Luan J, Shattuck-Brandt R, Richmond A (2000) J Leukoc Biol 67: 53-62 Distributions of melanoma growth stimulatory activity of growth-regulated gene and the interleukin-8 receptor B in human wound repair. Nanney LB, Mueller SG, Bueno R, Peiper SC, Richmond A (1995) Am J Pathol 147: 1248-60 Cytokine-induced neutrophil chemoattractant mediates neutrophilic alveolitis in rats: association with nuclear factor kappa B activation. Blackwell TS, Holden EP, Blackwell TR, DeLarco JE, Christman JW (1994) Am J Respir Cell Mol Biol 11: 464-72 High yield purification of melanoma growth stimulatory activity. Thomas HG, Richmond A (1988) Mol Cell Endocrinol 57: 69-76 Role of A2B adenosine receptors in regulation of paracrine functions of stem cell antigen 1-positive cardiac stromal cells. Ryzhov S, Goldstein AE, Novitskiy SV, Blackburn MR, Biaggioni I, Feoktistov I (2012) J Pharmacol Exp Ther 341: 764-74 Prostaglandin E2 induction during mouse adenovirus type 1 respiratory infection regulates inflammatory mediator generation but does not affect viral pathogenesis. McCarthy MK, Levine RE, Procario MC, McDonnell PJ, Zhu L, Mancuso P, Crofford LJ, Aronoff DM, Weinberg JB (2013) PLoS One 8: e77628 Expression of three forms of melanoma growth stimulating activity (MGSA)/gro in human retinal pigment epithelial cells. Jaffe GJ, Richmond A, Van Le L, Shattuck RL, Cheng QC, Wong F, Roberts W (1993) Invest Ophthalmol Vis Sci 34: 2776-85 Interruption of G protein-coupling in CXCR2 does not alter ligand binding, but eliminates ligand-activation of GTPgamma35S binding, calcium mobilization, and chemotaxis. Yang W, Schraw WP, Mueller SG, Richmond A (1997) Biochemistry 36: 15193-200 Melanoma growth stimulatory activity signaling through the class II interleukin-8 receptor enhances the tyrosine phosphorylation of Crk-associated substrate, p130, and a 70-kilodalton protein. Schraw W, Richmond A (1995) Biochemistry 34: 13760-7 Cell surface heparan sulfate participates in CXCL1-induced signaling. Wang D, Sai J, Richmond A (2003) Biochemistry 42: 1071-7 PAK1 kinase is required for CXCL1-induced chemotaxis. Wang D, Sai J, Carter G, Sachpatzidis A, Lolis E, Richmond A (2002) Biochemistry 41: 7100-7 Immunoaffinity purification of melanoma growth stimulatory activity. Thomas HG, Richmond A (1988) Arch Biochem Biophys 260: 719-24 Keratinocyte chemoattractant (KC)/human growth-regulated oncogene (GRO) chemokines and pro-inflammatory chemokine networks in mouse and human ovarian epithelial cancer cells. Son DS, Parl AK, Rice VM, Khabele D (2007) Cancer Biol Ther 6: 1302-12
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.