Keyword Connections

•  Brandt Eichman
•  Galina Lepesheva
•  Kyle Brown

•  Martin Egli
•  Nicole Perry
•  Richard Armstrong

•  Terunaga Nakagawa
•  Tina Iverson

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Publications

• Coronary calcium as a predictor of coronary events in four racial or ethnic groups.
  Detrano R, Guerci AD, Carr JJ, Bild DE, Burke G, Folsom AR, Liu K, Shea S, Szklo M, Bluemke DA, O'Leary DH, Tracy R, Watson K, Wong ND, Kronmal RA
  (2008) N Engl J Med 358: 1336-45
• Premature coronary-artery atherosclerosis in systemic lupus erythematosus.
  Asanuma Y, Oeser A, Shintani AK, Turner E, Olsen N, Fazio S, Linton MF, Raggi P, Stein CM
  (2003) N Engl J Med 349: 2407-15
• The index case for the fungal meningitis outbreak in the United States.
  Pettit AC, Kropski JA, Castilho JL, Schmitz JE, Rauch CA, Mobley BC, Wang XJ, Spires SS, Pugh ME
  (2012) N Engl J Med 367: 2119-25
• MUC5B promoter polymorphism and interstitial lung abnormalities.
  Hunninghake GM, Hatabu H, Okajima Y, Gao W, Dupuis J, Latourelle JC, Nishino M, Araki T, Zazueta OE, Kurugol S, Ross JC, San José Estépar R, Murphy E, Steele MP, Loyd JE, Schwarz MI, Fingerlin TE, Rosas IO, Washko GR, O'Connor GT, Schwartz DA
  (2013) N Engl J Med 368: 2192-200
• Constrictive bronchiolitis in soldiers returning from Iraq and Afghanistan.
  King MS, Eisenberg R, Newman JH, Tolle JJ, Harrell FE, Nian H, Ninan M, Lambright ES, Sheller JR, Johnson JE, Miller RF
  (2011) N Engl J Med 365: 222-30
• Estrogen therapy and coronary-artery calcification.
  Manson JE, Allison MA, Rossouw JE, Carr JJ, Langer RD, Hsia J, Kuller LH, Cochrane BB, Hunt JR, Ludlam SE, Pettinger MB, Gass M, Margolis KL, Nathan L, Ockene JK, Prentice RL, Robbins J, Stefanick ML, WHI and WHI-CACS Investigators
  (2007) N Engl J Med 356: 2591-602
• Percent emphysema, airflow obstruction, and impaired left ventricular filling.
  Barr RG, Bluemke DA, Ahmed FS, Carr JJ, Enright PL, Hoffman EA, Jiang R, Kawut SM, Kronmal RA, Lima JA, Shahar E, Smith LJ, Watson KE
  (2010) N Engl J Med 362: 217-27
• Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
  Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE
  (2015) Nature 523: 561-7
• Structural basis of ligand binding modes at the neuropeptide Y Y receptor.
  Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG, Buschauer A, Wu B
  (2018) Nature 556: 520-524
• GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4.
  Sondek J, Lambright DG, Noel JP, Hamm HE, Sigler PB
  (1994) Nature 372: 276-9
• An unprecedented nucleic acid capture mechanism for excision of DNA damage.
  Rubinson EH, Gowda AS, Spratt TE, Gold B, Eichman BF
  (2010) Nature 468: 406-11
• Structure of a bacterial ribonuclease P holoenzyme in complex with tRNA.
  Reiter NJ, Osterman A, Torres-Larios A, Swinger KK, Pan T, Mondragón A
  (2010) Nature 468: 784-9
• The 2.0 A crystal structure of a heterotrimeric G protein.
  Lambright DG, Sondek J, Bohm A, Skiba NP, Hamm HE, Sigler PB
  (1996) Nature 379: 311-9
• The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
  Mullins EA, Shi R, Parsons ZD, Yuen PK, David SS, Igarashi Y, Eichman BF
  (2015) Nature 527: 254-8
• Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation.
  Friedrich R, Panizzi P, Fuentes-Prior P, Richter K, Verhamme I, Anderson PJ, Kawabata S, Huber R, Bode W, Bock PE
  (2003) Nature 425: 535-9
• Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
  Karakas E, Simorowski N, Furukawa H
  (2011) Nature 475: 249-53
• Crystal structure of a G-protein beta gamma dimer at 2.1A resolution.
  Sondek J, Bohm A, Lambright DG, Hamm HE, Sigler PB
  (1996) Nature 379: 369-74
• Structure of tobacco mosaic virus at 6.7 å resolution.
  Holmes KC, Stubbs GJ, Mandelkow E, Gallwitz U
  (1975) Nature 254: 192-6
• Icosahedral bacteriophage ΦX174 forms a tail for DNA transport during infection.
  Sun L, Young LN, Zhang X, Boudko SP, Fokine A, Zbornik E, Roznowski AP, Molineux IJ, Rossmann MG, Fane BA
  (2014) Nature 505: 432-5
• Activation of NMDA receptors and the mechanism of inhibition by ifenprodil.
  Tajima N, Karakas E, Grant T, Simorowski N, Diaz-Avalos R, Grigorieff N, Furukawa H
  (2016) Nature 534: 63-8
• Structure of RNA and RNA binding site in tobacco mosaic virus from 4-A map calculated from X-ray fibre diagrams.
  Stubbs G, Warren S, Holmes K
  (1977) Nature 267: 216-21
• Structural biology: Anticancer drug target pictured.
  Waterman MR
  (2009) Nature 457: 159-60
• Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
  Huang DT, Hunt HW, Zhuang M, Ohi MD, Holton JM, Schulman BA
  (2007) Nature 445: 394-8
• Proof of principle for epitope-focused vaccine design.
  Correia BE, Bates JT, Loomis RJ, Baneyx G, Carrico C, Jardine JG, Rupert P, Correnti C, Kalyuzhniy O, Vittal V, Connell MJ, Stevens E, Schroeter A, Chen M, Macpherson S, Serra AM, Adachi Y, Holmes MA, Li Y, Klevit RE, Graham BS, Wyatt RT, Baker D, Strong RK, Crowe JE, Johnson PR, Schief WR
  (2014) Nature 507: 201-6
• Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein.
  Lambright DG, Noel JP, Hamm HE, Sigler PB
  (1994) Nature 369: 621-8
• NMR structure and mutagenesis of the FADD (Mort1) death-effector domain.
  Eberstadt M, Huang B, Chen Z, Meadows RP, Ng SC, Zheng L, Lenardo MJ, Fesik SW
  (1998) Nature 392: 941-5
• The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S.
  Noel JP, Hamm HE, Sigler PB
  (1993) Nature 366: 654-63
• X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
  Muchmore SW, Sattler M, Liang H, Meadows RP, Harlan JE, Yoon HS, Nettesheim D, Chang BS, Thompson CB, Wong SL, Ng SL, Fesik SW
  (1996) Nature 381: 335-41
• The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation.
  Hirsch JA, Schubert C, Gurevich VV, Sigler PB
  (1999) Cell 97: 257-69
• Structural basis for Marburg virus neutralization by a cross-reactive human antibody.
  Hashiguchi T, Fusco ML, Bornholdt ZA, Lee JE, Flyak AI, Matsuoka R, Kohda D, Yanagi Y, Hammel M, Crowe JE, Saphire EO
  (2015) Cell 160: 904-912
• The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2.
  Wall MA, Coleman DE, Lee E, Iñiguez-Lluhi JA, Posner BA, Gilman AG, Sprang SR
  (1995) Cell 83: 1047-58
• The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
  Minor DL, Lin YF, Mobley BC, Avelar A, Jan YN, Jan LY, Berger JM
  (2000) Cell 102: 657-70
• Phosphoinositide binding domains: embracing 3-phosphate.
  Fruman DA, Rameh LE, Cantley LC
  (1999) Cell 97: 817-20
• Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.
  Zhou XE, He Y, de Waal PW, Gao X, Kang Y, Van Eps N, Yin Y, Pal K, Goswami D, White TA, Barty A, Latorraca NR, Chapman HN, Hubbell WL, Dror RO, Stevens RC, Cherezov V, Gurevich VV, Griffin PR, Ernst OP, Melcher K, Xu HE
  (2017) Cell 170: 457-469.e13
• Structure and dynamics of AMPA receptor GluA2 in resting, pre-open, and desensitized states.
  Dürr KL, Chen L, Stein RA, De Zorzi R, Folea IM, Walz T, Mchaourab HS, Gouaux E
  (2014) Cell 158: 778-792
• Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G.
  Stewart-Jones GB, Soto C, Lemmin T, Chuang GY, Druz A, Kong R, Thomas PV, Wagh K, Zhou T, Behrens AJ, Bylund T, Choi CW, Davison JR, Georgiev IS, Joyce MG, Kwon YD, Pancera M, Taft J, Yang Y, Zhang B, Shivatare SS, Shivatare VS, Lee CC, Wu CY, Bewley CA, Burton DR, Koff WC, Connors M, Crispin M, Baxa U, Korber BT, Wong CH, Mascola JR, Kwong PD
  (2016) Cell 165: 813-26
• Tertiary and quaternary structural changes in Gi alpha 1 induced by GTP hydrolysis.
  Mixon MB, Lee E, Coleman DE, Berghuis AM, Gilman AG, Sprang SR
  (1995) Science 270: 954-60
• Structural biology. Controlling the caspases.
  Fesik SW, Shi Y
  (2001) Science 294: 1477-8
• Structural changes in bacteriorhodopsin during ion transport at 2 angstrom resolution.
  Luecke H, Schobert B, Richter HT, Cartailler JP, Lanyi JK
  (1999) Science 286: 255-61