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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Publications
- Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1.
Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, Newgard CB, Spiegelman BM
(2001) Nature 413: 131-8 - Hypothalamic CART is a new anorectic peptide regulated by leptin.
Kristensen P, Judge ME, Thim L, Ribel U, Christjansen KN, Wulff BS, Clausen JT, Jensen PB, Madsen OD, Vrang N, Larsen PJ, Hastrup S
(1998) Nature 393: 72-6 - A piece of my mind. Fulfilling our leadership responsibility.
Gorrindo P, Tedeschi SK, Powers AR, Niswender K
(2013) JAMA 309: 147-8 - Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells.
Tornovsky-Babeay S, Dadon D, Ziv O, Tzipilevich E, Kadosh T, Schyr-Ben Haroush R, Hija A, Stolovich-Rain M, Furth-Lavi J, Granot Z, Porat S, Philipson LH, Herold KC, Bhatti TR, Stanley C, Ashcroft FM, In't Veld P, Saada A, Magnuson MA, Glaser B, Dor Y
(2014) Cell Metab 19: 109-21 - Insulin signaling in alpha cells modulates glucagon secretion in vivo.
Kawamori D, Kurpad AJ, Hu J, Liew CW, Shih JL, Ford EL, Herrera PL, Polonsky KS, McGuinness OP, Kulkarni RN
(2009) Cell Metab 9: 350-61 - Monocyte-T lymphocyte interaction for regulation of insulin receptors of the activated T lymphocyte.
Helderman JH, Ayuso R, Rosenstock J, Raskin P
(1987) J Clin Invest 79: 566-71 - The role of insulin and glucagon in the regulation of basal glucose production in the postabsorptive dog.
Cherrington AD, Chiasson JL, Liljenquist JE, Jennings AS, Keller U, Lacy WW
(1976) J Clin Invest 58: 1407-18 - Renal contribution to glucose production after a brief fast: fact or fancy?
Cherrington AD, Wasserman DH, McGinness OP
(1994) J Clin Invest 93: 2303 - Insulin's direct effects on the liver dominate the control of hepatic glucose production.
Edgerton DS, Lautz M, Scott M, Everett CA, Stettler KM, Neal DW, Chu CA, Cherrington AD
(2006) J Clin Invest 116: 521-7 - Importance of the route of intravenous glucose delivery to hepatic glucose balance in the conscious dog.
Adkins BA, Myers SR, Hendrick GK, Stevenson RW, Williams PE, Cherrington AD
(1987) J Clin Invest 79: 557-65 - Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.
Liu CT, Raghavan S, Maruthur N, Kabagambe EK, Hong J, Ng MC, Hivert MF, Lu Y, An P, Bentley AR, Drolet AM, Gaulton KJ, Guo X, Armstrong LL, Irvin MR, Li M, Lipovich L, Rybin DV, Taylor KD, Agyemang C, Palmer ND, Cade BE, Chen WM, Dauriz M, Delaney JA, Edwards TL, Evans DS, Evans MK, Lange LA, Leong A, Liu J, Liu Y, Nayak U, Patel SR, Porneala BC, Rasmussen-Torvik LJ, Snijder MB, Stallings SC, Tanaka T, Yanek LR, Zhao W, Becker DM, Bielak LF, Biggs ML, Bottinger EP, Bowden DW, Chen G, Correa A, Couper DJ, Crawford DC, Cushman M, Eicher JD, Fornage M, Franceschini N, Fu YP, Goodarzi MO, Gottesman O, Hara K, Harris TB, Jensen RA, Johnson AD, Jhun MA, Karter AJ, Keller MF, Kho AN, Kizer JR, Krauss RM, Langefeld CD, Li X, Liang J, Liu S, Lowe WL, Mosley TH, North KE, Pacheco JA, Peyser PA, Patrick AL, Rice KM, Selvin E, Sims M, Smith JA, Tajuddin SM, Vaidya D, Wren MP, Yao J, Zhu X, Ziegler JT, Zmuda JM, Zonderman AB, Zwinderman AH, AAAG Consortium, CARe Consortium, COGENT-BP Consortium, eMERGE Consortium, MEDIA Consortium, Adeyemo A, Boerwinkle E, Ferrucci L, Hayes MG, Kardia SL, Miljkovic I, Pankow JS, Rotimi CN, Sale MM, Wagenknecht LE, Arnett DK, Chen YD, Nalls MA, MAGIC Consortium, Province MA, Kao WH, Siscovick DS, Psaty BM, Wilson JG, Loos RJ, Dupuis J, Rich SS, Florez JC, Rotter JI, Morris AP, Meigs JB
(2016) Am J Hum Genet 99: 56-75 - Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected].
Stiles B, Wang Y, Stahl A, Bassilian S, Lee WP, Kim YJ, Sherwin R, Devaskar S, Lesche R, Magnuson MA, Wu H
(2004) Proc Natl Acad Sci U S A 101: 2082-7 - Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes.
Imai T, Jiang M, Chambon P, Metzger D
(2001) Proc Natl Acad Sci U S A 98: 224-8 - Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids.
Morrow JD, Awad JA, Boss HJ, Blair IA, Roberts LJ
(1992) Proc Natl Acad Sci U S A 89: 10721-5 - Melanocortin-3 receptor regulates the normal fasting response.
Renquist BJ, Murphy JG, Larson EA, Olsen D, Klein RF, Ellacott KL, Cone RD
(2012) Proc Natl Acad Sci U S A 109: E1489-98 - The amino acid-induced alteration in renal hemodynamics is glucagon independent.
Nammour TM, Williams PE, Badr KF, Abumrad NN, Jacobson HR
(1991) J Am Soc Nephrol 2: 164-71 - Hexokinase II overexpression improves exercise-stimulated but not insulin-stimulated muscle glucose uptake in high-fat-fed C57BL/6J mice.
Fueger PT, Bracy DP, Malabanan CM, Pencek RR, Granner DK, Wasserman DH
(2004) Diabetes 53: 306-14 - Effects of fasting on gluconeogenesis from alanine in nondiabetic man.
Chiasson JL, Atkinson RL, Cherrington AD, Keller U, Sinclair-Smith BC, Lacy WW, Liljenquist JE
(1979) Diabetes 28: 56-60 - Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo.
Edgerton DS, Ramnanan CJ, Grueter CA, Johnson KM, Lautz M, Neal DW, Williams PE, Cherrington AD
(2009) Diabetes 58: 2766-75 - The roles of insulin and glucagon in the regulation of gluconeogenesis in the postabsorptive dog.
Jennings AS, Cherrington AD, Liljenquist JE, Keller U, Lacy WW, Chiasson JL
(1977) Diabetes 26: 847-56 - Direct and indirect effects of insulin on glucose uptake and storage by the liver.
Satake S, Moore MC, Igawa K, Converse M, Farmer B, Neal DW, Cherrington AD
(2002) Diabetes 51: 1663-71 - Insulin sensitively controls the glucagon response to mild hypoglycemia in the dog.
Igawa K, Mugavero M, Shiota M, Neal DW, Cherrington AD
(2002) Diabetes 51: 3033-42 - Inhalation of human insulin (exubera) augments the efficiency of muscle glucose uptake in vivo.
Edgerton DS, Cherrington AD, Williams P, Neal DW, Scott M, Bowen L, Wilson W, Hobbs CH, Leach C, Kuo MC, Strack TR
(2006) Diabetes 55: 3604-10 - A Low-Frequency Inactivating Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, Flannick J, Fuchsberger C, Gamazon ER, Gaulton KJ, Im HK, Teslovich TM, Blackwell TW, Bork-Jensen J, Burtt NP, Chen Y, Green T, Hartl C, Kang HM, Kumar A, Ladenvall C, Ma C, Moutsianas L, Pearson RD, Perry JRB, Rayner NW, Robertson NR, Scott LJ, van de Bunt M, Eriksson JG, Jula A, Koskinen S, Lehtimäki T, Palotie A, Raitakari OT, Jacobs SBR, Wessel J, Chu AY, Scott RA, Goodarzi MO, Blancher C, Buck G, Buck D, Chines PS, Gabriel S, Gjesing AP, Groves CJ, Hollensted M, Huyghe JR, Jackson AU, Jun G, Justesen JM, Mangino M, Murphy J, Neville M, Onofrio R, Small KS, Stringham HM, Trakalo J, Banks E, Carey J, Carneiro MO, DePristo M, Farjoun Y, Fennell T, Goldstein JI, Grant G, Hrabé de Angelis M, Maguire J, Neale BM, Poplin R, Purcell S, Schwarzmayr T, Shakir K, Smith JD, Strom TM, Wieland T, Lindstrom J, Brandslund I, Christensen C, Surdulescu GL, Lakka TA, Doney ASF, Nilsson P, Wareham NJ, Langenberg C, Varga TV, Franks PW, Rolandsson O, Rosengren AH, Farook VS, Thameem F, Puppala S, Kumar S, Lehman DM, Jenkinson CP, Curran JE, Hale DE, Fowler SP, Arya R, DeFronzo RA, Abboud HE, Syvänen AC, Hicks PJ, Palmer ND, Ng MCY, Bowden DW, Freedman BI, Esko T, Mägi R, Milani L, Mihailov E, Metspalu A, Narisu N, Kinnunen L, Bonnycastle LL, Swift A, Pasko D, Wood AR, Fadista J, Pollin TI, Barzilai N, Atzmon G, Glaser B, Thorand B, Strauch K, Peters A, Roden M, Müller-Nurasyid M, Liang L, Kriebel J, Illig T, Grallert H, Gieger C, Meisinger C, Lannfelt L, Musani SK, Griswold M, Taylor HA, Wilson G, Correa A, Oksa H, Scott WR, Afzal U, Tan ST, Loh M, Chambers JC, Sehmi J, Kooner JS, Lehne B, Cho YS, Lee JY, Han BG, Käräjämäki A, Qi Q, Qi L, Huang J, Hu FB, Melander O, Orho-Melander M, Below JE, Aguilar D, Wong TY, Liu J, Khor CC, Chia KS, Lim WY, Cheng CY, Chan E, Tai ES, Aung T, Linneberg A, Isomaa B, Meitinger T, Tuomi T, Hakaste L, Kravic J, Jørgensen ME, Lauritzen T, Deloukas P, Stirrups KE, Owen KR, Farmer AJ, Frayling TM, O'Rahilly SP, Walker M, Levy JC, Hodgkiss D, Hattersley AT, Kuulasmaa T, Stančáková A, Barroso I, Bharadwaj D, Chan J, Chandak GR, Daly MJ, Donnelly PJ, Ebrahim SB, Elliott P, Fingerlin T, Froguel P, Hu C, Jia W, Ma RCW, McVean G, Park T, Prabhakaran D, Sandhu M, Scott J, Sladek R, Tandon N, Teo YY, Zeggini E, Watanabe RM, Koistinen HA, Kesaniemi YA, Uusitupa M, Spector TD, Salomaa V, Rauramaa R, Palmer CNA, Prokopenko I, Morris AD, Bergman RN, Collins FS, Lind L, Ingelsson E, Tuomilehto J, Karpe F, Groop L, Jørgensen T, Hansen T, Pedersen O, Kuusisto J, Abecasis G, Bell GI, Blangero J, Cox NJ, Duggirala R, Seielstad M, Wilson JG, Dupuis J, Ripatti S, Hanis CL, Florez JC, Mohlke KL, Meigs JB, Laakso M, Morris AP, Boehnke M, Altshuler D, McCarthy MI, Gloyn AL, Lindgren CM
(2017) Diabetes 66: 2019-2032 - Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.
Hwang JY, Sim X, Wu Y, Liang J, Tabara Y, Hu C, Hara K, Tam CH, Cai Q, Zhao Q, Jee S, Takeuchi F, Go MJ, Ong RT, Ohkubo T, Kim YJ, Zhang R, Yamauchi T, So WY, Long J, Gu D, Lee NR, Kim S, Katsuya T, Oh JH, Liu J, Umemura S, Kim YJ, Jiang F, Maeda S, Chan JC, Lu W, Hixson JE, Adair LS, Jung KJ, Nabika T, Bae JB, Lee MH, Seielstad M, Young TL, Teo YY, Kita Y, Takashima N, Osawa H, Lee SH, Shin MH, Shin DH, Choi BY, Shi J, Gao YT, Xiang YB, Zheng W, Kato N, Yoon M, He J, Shu XO, Ma RC, Kadowaki T, Jia W, Miki T, Qi L, Tai ES, Mohlke KL, Han BG, Cho YS, Kim BJ
(2015) Diabetes 64: 291-8 - The roles of insulin, glucagon, and free fatty acids in the regulation of ketogenesis in dogs.
Keller U, Chiasson JL, Liljenquist JE, Cherrington AD, Jennings AS, Crofford OS
(1977) Diabetes 26: 1040-51 - Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.
Hayes MG, Urbanek M, Hivert MF, Armstrong LL, Morrison J, Guo C, Lowe LP, Scheftner DA, Pluzhnikov A, Levine DM, McHugh CP, Ackerman CM, Bouchard L, Brisson D, Layden BT, Mirel D, Doheny KF, Leya MV, Lown-Hecht RN, Dyer AR, Metzger BE, Reddy TE, Cox NJ, Lowe WL, HAPO Study Cooperative Research Group
(2013) Diabetes 62: 3282-91 - AMP kinase-induced skeletal muscle glucose but not long-chain fatty acid uptake is dependent on nitric oxide.
Shearer J, Fueger PT, Vorndick B, Bracy DP, Rottman JN, Clanton JA, Wasserman DH
(2004) Diabetes 53: 1429-35 - Magnitude of negative arterial-portal glucose gradient alters net hepatic glucose balance in conscious dogs.
Pagliassotti MJ, Myers SR, Moore MC, Neal DW, Cherrington AD
(1991) Diabetes 40: 1659-68 - Interaction between insulin and glucose-delivery route in regulation of net hepatic glucose uptake in conscious dogs.
Adkins-Marshall BA, Myers SR, Hendrick GK, Williams PE, Triebwasser K, Floyd B, Cherrington AD
(1990) Diabetes 39: 87-95 - Basal hepatic glucose production is regulated by the portal vein insulin concentration.
Sindelar DK, Chu CA, Venson P, Donahue EP, Neal DW, Cherrington AD
(1998) Diabetes 47: 523-9 - Targeted disruption of G0/G1 switch gene 2 enhances adipose lipolysis, alters hepatic energy balance, and alleviates high-fat diet-induced liver steatosis.
Zhang X, Xie X, Heckmann BL, Saarinen AM, Czyzyk TA, Liu J
(2014) Diabetes 63: 934-46 - Regulation of ketogenesis by epinephrine and norepinephrine in the overnight-fasted, conscious dog.
Steiner KE, Fuchs H, Williams PE, Stevenson RW, Cherrington AD, Alberti KG
(1985) Diabetes 34: 425-32 - A new approach for diagnosing type 1 diabetes in autoantibody-positive individuals based on prediction and natural history.
Sosenko JM, Skyler JS, DiMeglio LA, Beam CA, Krischer JP, Greenbaum CJ, Boulware D, Rafkin LE, Matheson D, Herold KC, Mahon J, Palmer JP, Type 1 Diabetes TrialNet Study Group, Diabetes Prevention Trial-Type 1 Study Group
(2015) Diabetes Care 38: 271-6 - The importance of caloric restriction in the early improvements in insulin sensitivity after Roux-en-Y gastric bypass surgery.
Isbell JM, Tamboli RA, Hansen EN, Saliba J, Dunn JP, Phillips SE, Marks-Shulman PA, Abumrad NN
(2010) Diabetes Care 33: 1438-42 - Relationship of dopamine type 2 receptor binding potential with fasting neuroendocrine hormones and insulin sensitivity in human obesity.
Dunn JP, Kessler RM, Feurer ID, Volkow ND, Patterson BW, Ansari MS, Li R, Marks-Shulman P, Abumrad NN
(2012) Diabetes Care 35: 1105-11 - The -256T>C polymorphism in the apolipoprotein A-II gene promoter is associated with body mass index and food intake in the genetics of lipid lowering drugs and diet network study.
Corella D, Arnett DK, Tsai MY, Kabagambe EK, Peacock JM, Hixson JE, Straka RJ, Province M, Lai CQ, Parnell LD, Borecki I, Ordovas JM
(2007) Clin Chem 53: 1144-52 - Population-based study of alpha- and gamma-tocopherol in plasma and adipose tissue as biomarkers of intake in Costa Rican adults.
El-Sohemy A, Baylin A, Ascherio A, Kabagambe E, Spiegelman D, Campos H
(2001) Am J Clin Nutr 74: 356-63 - Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels.
Baerenwald DA, Bonnefond A, Bouatia-Naji N, Flemming BP, Umunakwe OC, Oeser JK, Pound LD, Conley NL, Cauchi S, Lobbens S, Eury E, Balkau B, Lantieri O, MAGIC Investigators, Dadi PK, Jacobson DA, Froguel P, O'Brien RM
(2013) Diabetologia 56: 1306-16 - Short-term regulation of insulin-mediated glucose utilization in four-day fasted human volunteers: role of amino acid availability.
Flakoll PJ, Wentzel LS, Rice DE, Hill JO, Abumrad NN
(1992) Diabetologia 35: 357-66
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