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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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- Human genetics: an expression of interest.
Cox NJ
(2004) Nature 430: 733-4 - A genome-wide linkage and association scan reveals novel loci for autism.
Weiss LA, Arking DE, Gene Discovery Project of Johns Hopkins & the Autism Consortium, Daly MJ, Chakravarti A
(2009) Nature 461: 802-8 - A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus.
Concannon P, Gogolin-Ewens KJ, Hinds DA, Wapelhorst B, Morrison VA, Stirling B, Mitra M, Farmer J, Williams SR, Cox NJ, Bell GI, Risch N, Spielman RS
(1998) Nat Genet 19: 292-6 - Mapping autism risk loci using genetic linkage and chromosomal rearrangements.
Autism Genome Project Consortium, Szatmari P, Paterson AD, Zwaigenbaum L, Roberts W, Brian J, Liu XQ, Vincent JB, Skaug JL, Thompson AP, Senman L, Feuk L, Qian C, Bryson SE, Jones MB, Marshall CR, Scherer SW, Vieland VJ, Bartlett C, Mangin LV, Goedken R, Segre A, Pericak-Vance MA, Cuccaro ML, Gilbert JR, Wright HH, Abramson RK, Betancur C, Bourgeron T, Gillberg C, Leboyer M, Buxbaum JD, Davis KL, Hollander E, Silverman JM, Hallmayer J, Lotspeich L, Sutcliffe JS, Haines JL, Folstein SE, Piven J, Wassink TH, Sheffield V, Geschwind DH, Bucan M, Brown WT, Cantor RM, Constantino JN, Gilliam TC, Herbert M, Lajonchere C, Ledbetter DH, Lese-Martin C, Miller J, Nelson S, Samango-Sprouse CA, Spence S, State M, Tanzi RE, Coon H, Dawson G, Devlin B, Estes A, Flodman P, Klei L, McMahon WM, Minshew N, Munson J, Korvatska E, Rodier PM, Schellenberg GD, Smith M, Spence MA, Stodgell C, Tepper PG, Wijsman EM, Yu CE, Rogé B, Mantoulan C, Wittemeyer K, Poustka A, Felder B, Klauck SM, Schuster C, Poustka F, Bölte S, Feineis-Matthews S, Herbrecht E, Schmötzer G, Tsiantis J, Papanikolaou K, Maestrini E, Bacchelli E, Blasi F, Carone S, Toma C, Van Engeland H, de Jonge M, Kemner C, Koop F, Koop F, Langemeijer M, Langemeijer M, Hijmans C, Hijimans C, Staal WG, Baird G, Bolton PF, Rutter ML, Weisblatt E, Green J, Aldred C, Wilkinson JA, Pickles A, Le Couteur A, Berney T, McConachie H, Bailey AJ, Francis K, Honeyman G, Hutchinson A, Parr JR, Wallace S, Monaco AP, Barnby G, Kobayashi K, Lamb JA, Sousa I, Sykes N, Cook EH, Guter SJ, Leventhal BL, Salt J, Lord C, Corsello C, Hus V, Weeks DE, Volkmar F, Tauber M, Fombonne E, Shih A, Meyer KJ
(2007) Nat Genet 39: 319-28 - Secretory COPII coat component Sec23a is essential for craniofacial chondrocyte maturation.
Lang MR, Lapierre LA, Frotscher M, Goldenring JR, Knapik EW
(2006) Nat Genet 38: 1198-203 - Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans.
Cox NJ, Frigge M, Nicolae DL, Concannon P, Hanis CL, Bell GI, Kong A
(1999) Nat Genet 21: 213-5 - Germline BAP1 mutations predispose to malignant mesothelioma.
Testa JR, Cheung M, Pei J, Below JE, Tan Y, Sementino E, Cox NJ, Dogan AU, Pass HI, Trusa S, Hesdorffer M, Nasu M, Powers A, Rivera Z, Comertpay S, Tanji M, Gaudino G, Yang H, Carbone M
(2011) Nat Genet 43: 1022-5 - MERLIN...and the geneticist's stone?
Nicolae DL, Cox NJ
(2002) Nat Genet 30: 3-4 - A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.
Hanis CL, Boerwinkle E, Chakraborty R, Ellsworth DL, Concannon P, Stirling B, Morrison VA, Wapelhorst B, Spielman RS, Gogolin-Ewens KJ, Shepard JM, Williams SR, Risch N, Hinds D, Iwasaki N, Ogata M, Omori Y, Petzold C, Rietzch H, Schröder HE, Schulze J, Cox NJ, Menzel S, Boriraj VV, Chen X, Lim LR, Lindner T, Mereu LE, Wang YQ, Xiang K, Yamagata K, Yang Y, Bell GI
(1996) Nat Genet 13: 161-6 - Molecular basis of human hypertension: role of angiotensinogen.
Jeunemaitre X, Soubrier F, Kotelevtsev YV, Lifton RP, Williams CS, Charru A, Hunt SC, Hopkins PN, Williams RR, Lalouel JM
(1992) Cell 71: 169-80 - Heritability and genetic linkage of plasma natriuretic peptide levels.
Wang TJ, Larson MG, Levy D, Benjamin EJ, Corey D, Leip EP, Vasan RS
(2003) Circulation 108: 13-6 - Heritability, linkage, and genetic associations of exercise treadmill test responses.
Ingelsson E, Larson MG, Vasan RS, O'Donnell CJ, Yin X, Hirschhorn JN, Newton-Cheh C, Drake JA, Musone SL, Heard-Costa NL, Benjamin EJ, Levy D, Atwood LD, Wang TJ, Kathiresan S
(2007) Circulation 115: 2917-24 - SZGR: a comprehensive schizophrenia gene resource.
Jia P, Sun J, Guo AY, Zhao Z
(2010) Mol Psychiatry 15: 453-62 - Evidence of linkage between the serotonin transporter and autistic disorder.
Cook EH, Courchesne R, Lord C, Cox NJ, Yan S, Lincoln A, Haas R, Courchesne E, Leventhal BL
(1997) Mol Psychiatry 2: 247-50 - Resistance to Leishmania major is linked to the H2 region on chromosome 17 and to chromosome 9.
Roberts LJ, Baldwin TM, Curtis JM, Handman E, Foote SJ
(1997) J Exp Med 185: 1705-10 - Comparative distribution of the alpha 1(IV), alpha 5(IV), and alpha 6(IV) collagen chains in normal human adult and fetal tissues and in kidneys from X-linked Alport syndrome patients.
Peissel B, Geng L, Kalluri R, Kashtan C, Rennke HG, Gallo GR, Yoshioka K, Sun MJ, Hudson BG, Neilson EG
(1995) J Clin Invest 96: 1948-57 - Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure.
Colilla S, Nicolae D, Pluzhnikov A, Blumenthal MN, Beaty TH, Bleecker ER, Lange EM, Rich SS, Meyers DA, Ober C, Cox NJ, Collaborative Study for the Genetics of Asthma
(2003) J Allergy Clin Immunol 111: 840-6 - Locus on chromosome 6p linked to elevated HDL cholesterol serum levels and to protection against premature atherosclerosis in a kindred with familial hypercholesterolemia.
Canizales-Quinteros S, Aguilar-Salinas CA, Reyes-Rodríguez E, Riba L, Rodríguez-Torres M, Ramírez-Jiménez S, Huertas-Vázquez A, Fragoso-Ontiveros V, Zentella-Dehesa A, Ventura-Gallegos JL, Vega-Hernández G, López-Estrada A, Aurón-Gómez M, Gómez-Pérez F, Rull J, Cox NJ, Bell GI, Tusié-Luna MT
(2003) Circ Res 92: 569-76 - Accurate inference of relationships in sib-pair linkage studies.
Boehnke M, Cox NJ
(1997) Am J Hum Genet 61: 423-9 - Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: collaborative study on the genetics of asthma.
Xu J, Meyers DA, Ober C, Blumenthal MN, Mellen B, Barnes KC, King RA, Lester LA, Howard TD, Solway J, Langefeld CD, Beaty TH, Rich SS, Bleecker ER, Cox NJ, Collaborative Study on the Genetics of Asthma
(2001) Am J Hum Genet 68: 1437-46 - Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors.
Sutcliffe JS, Delahanty RJ, Prasad HC, McCauley JL, Han Q, Jiang L, Li C, Folstein SE, Blakely RD
(2005) Am J Hum Genet 77: 265-79 - Genomewide significant linkage to stuttering on chromosome 12.
Riaz N, Steinberg S, Ahmad J, Pluzhnikov A, Riazuddin S, Cox NJ, Drayna D
(2005) Am J Hum Genet 76: 647-51 - Allele-sharing models: LOD scores and accurate linkage tests.
Kong A, Cox NJ
(1997) Am J Hum Genet 61: 1179-88 - Linkage disequilibrium in the human insulin/insulin-like growth factor II region of human chromosome II.
Cox NJ, Bell GI, Xiang KS
(1988) Am J Hum Genet 43: 495-501 - Mental retardation and abnormal skeletal development (Dyggve-Melchior-Clausen dysplasia) due to mutations in a novel, evolutionarily conserved gene.
Cohn DH, Ehtesham N, Krakow D, Unger S, Shanske A, Reinker K, Powell BR, Rimoin DL
(2003) Am J Hum Genet 72: 419-28 - Localization of juvenile, but not late-infantile, neuronal ceroid lipofuscinosis on chromosome 16.
Yan W, Boustany RM, Konradi C, Ozelius L, Lerner T, Trofatter JA, Julier C, Breakefield XO, Gusella JF, Haines JL
(1993) Am J Hum Genet 52: 89-95 - Shwachman-Diamond syndrome with exocrine pancreatic dysfunction and bone marrow failure maps to the centromeric region of chromosome 7.
Goobie S, Popovic M, Morrison J, Ellis L, Ginzberg H, Boocock GR, Ehtesham N, Bétard C, Brewer CG, Roslin NM, Hudson TJ, Morgan K, Fujiwara TM, Durie PR, Rommens JM
(2001) Am J Hum Genet 68: 1048-54 - Insulin-gene sharing in sib pairs with insulin-dependent diabetes mellitus: no evidence for linkage.
Cox NJ, Baker L, Spielman RS
(1988) Am J Hum Genet 42: 167-72 - A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
Ober C, Tsalenko A, Parry R, Cox NJ
(2000) Am J Hum Genet 67: 1154-62 - Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample.
Suarez BK, Duan J, Sanders AR, Hinrichs AL, Jin CH, Hou C, Buccola NG, Hale N, Weilbaecher AN, Nertney DA, Olincy A, Green S, Schaffer AW, Smith CJ, Hannah DE, Rice JP, Cox NJ, Martinez M, Mowry BJ, Amin F, Silverman JM, Black DW, Byerley WF, Crowe RR, Freedman R, Cloninger CR, Levinson DF, Gejman PV
(2006) Am J Hum Genet 78: 315-33 - Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families.
Cox NJ, Wapelhorst B, Morrison VA, Johnson L, Pinchuk L, Spielman RS, Todd JA, Concannon P
(2001) Am J Hum Genet 69: 820-30 - Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.
Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, Walker M, Levy JC, O'Rahilly S, Rao PV, Bennett AJ, Jones EC, Menzel S, Prestwich P, Simecek N, Wishart M, Dhillon R, Fletcher C, Millward A, Demaine A, Wilkin T, Horikawa Y, Cox NJ, Bell GI, Ellard S, McCarthy MI, Hattersley AT
(2001) Am J Hum Genet 69: 544-52 - The importance of genealogy in determining genetic associations with complex traits.
Newman DL, Abney M, McPeek MS, Ober C, Cox NJ
(2001) Am J Hum Genet 69: 1146-8 - A statistical method for identification of polymorphisms that explain a linkage result.
Sun L, Cox NJ, McPeek MS
(2002) Am J Hum Genet 70: 399-411 - Survey of the fragile X syndrome CGG repeat and the short-tandem-repeat and single-nucleotide-polymorphism haplotypes in an African American population.
Crawford DC, Schwartz CE, Meadows KL, Newman JL, Taft LF, Gunter C, Brown WT, Carpenter NJ, Howard-Peebles PN, Monaghan KG, Nolin SL, Reiss AL, Feldman GL, Rohlfs EM, Warren ST, Sherman SL
(2000) Am J Hum Genet 66: 480-93 - Importance sampling. I. Computing multimodel p values in linkage analysis.
Kong A, Frigge M, Irwin M, Cox N
(1992) Am J Hum Genet 51: 1413-29 - CTDGFinder: A Novel Homology-Based Algorithm for Identifying Closely Spaced Clusters of Tandemly Duplicated Genes.
Ortiz JF, Rokas A
(2017) Mol Biol Evol 34: 215-229 - Shared Selective Pressures on Fungal and Human Metabolic Pathways Lead to Divergent yet Analogous Genetic Responses.
Eidem HR, McGary KL, Rokas A
(2015) Mol Biol Evol 32: 1449-55 - A major zebrafish polymorphism resource for genetic mapping.
Bradley KM, Elmore JB, Breyer JP, Yaspan BL, Jessen JR, Knapik EW, Smith JR
(2007) Genome Biol 8: R55 - Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q.
Bell GI, Xiang KS, Newman MV, Wu SH, Wright LG, Fajans SS, Spielman RS, Cox NJ
(1991) Proc Natl Acad Sci U S A 88: 1484-8
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