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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Norepinephrine Plasma Membrane Transport Proteins are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Norepinephrine Plasma Membrane Transport Proteins.
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Publications
- Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency.
Shannon JR, Flattem NL, Jordan J, Jacob G, Black BK, Biaggioni I, Blakely RD, Robertson D
(2000) N Engl J Med 342: 541-9 - Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter.
Pacholczyk T, Blakely RD, Amara SG
(1991) Nature 350: 350-4 - Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine.
Pirzgalska RM, Seixas E, Seidman JS, Link VM, Sánchez NM, Mahú I, Mendes R, Gres V, Kubasova N, Morris I, Arús BA, Larabee CM, Vasques M, Tortosa F, Sousa AL, Anandan S, Tranfield E, Hahn MK, Iannacone M, Spann NJ, Glass CK, Domingos AI
(2017) Nat Med 23: 1309-1318 - Paradoxical effect of sibutramine on autonomic cardiovascular regulation.
Birkenfeld AL, Schroeder C, Boschmann M, Tank J, Franke G, Luft FC, Biaggioni I, Sharma AM, Jordan J
(2002) Circulation 106: 2459-65 - Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles.
Vincent S, Bieck PR, Garland EM, Loghin C, Bymaster FP, Black BK, Gonzales C, Potter WZ, Robertson D
(2004) Circulation 109: 3202-7 - A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder.
Kim CH, Hahn MK, Joung Y, Anderson SL, Steele AH, Mazei-Robinson MS, Gizer I, Teicher MH, Cohen BM, Robertson D, Waldman ID, Blakely RD, Kim KS
(2006) Proc Natl Acad Sci U S A 103: 19164-9 - Patch-clamp and amperometric recordings from norepinephrine transporters: channel activity and voltage-dependent uptake.
Galli A, Blakely RD, DeFelice LJ
(1998) Proc Natl Acad Sci U S A 95: 13260-5 - Norepinephrine transporters have channel modes of conduction.
Galli A, Blakely RD, DeFelice LJ
(1996) Proc Natl Acad Sci U S A 93: 8671-6 - Alpha1-adrenergic receptor-induced heterosynaptic long-term depression in the bed nucleus of the stria terminalis is disrupted in mouse models of affective disorders.
McElligott ZA, Winder DG
(2008) Neuropsychopharmacology 33: 2313-23 - Yohimbine depresses excitatory transmission in BNST and impairs extinction of cocaine place preference through orexin-dependent, norepinephrine-independent processes.
Conrad KL, Davis AR, Silberman Y, Sheffler DJ, Shields AD, Saleh SA, Sen N, Matthies HJ, Javitch JA, Lindsley CW, Winder DG
(2012) Neuropsychopharmacology 37: 2253-66 - Rab11 supports amphetamine-stimulated norepinephrine transporter trafficking.
Matthies HJ, Moore JL, Saunders C, Matthies DS, Lapierre LA, Goldenring JR, Blakely RD, Galli A
(2010) J Neurosci 30: 7863-77 - Molecular cloning and characterization of an L-epinephrine transporter from sympathetic ganglia of the bullfrog, Rana catesbiana.
Apparsundaram S, Moore KR, Malone MD, Hartzell HC, Blakely RD
(1997) J Neurosci 17: 2691-702 - Physiological genomics of antidepressant targets: keeping the periphery in mind.
Blakely RD
(2001) J Neurosci 21: 8319-23 - Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A.
Bauman AL, Apparsundaram S, Ramamoorthy S, Wadzinski BE, Vaughan RA, Blakely RD
(2000) J Neurosci 20: 7571-8 - A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity.
Sung U, Apparsundaram S, Galli A, Kahlig KM, Savchenko V, Schroeter S, Quick MW, Blakely RD
(2003) J Neurosci 23: 1697-709 - A mutation in the human norepinephrine transporter gene (SLC6A2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters.
Hahn MK, Robertson D, Blakely RD
(2003) J Neurosci 23: 4470-8 - Chronic stress increases the plasmalemmal distribution of the norepinephrine transporter and the coexpression of tyrosine hydroxylase in norepinephrine axons in the prefrontal cortex.
Miner LH, Jedema HP, Moore FW, Blakely RD, Grace AA, Sesack SR
(2006) J Neurosci 26: 1571-8 - Insulin reveals Akt signaling as a novel regulator of norepinephrine transporter trafficking and norepinephrine homeostasis.
Robertson SD, Matthies HJ, Owens WA, Sathananthan V, Christianson NS, Kennedy JP, Lindsley CW, Daws LC, Galli A
(2010) J Neurosci 30: 11305-16 - Dependence of serotonergic and other nonadrenergic enteric neurons on norepinephrine transporter expression.
Li Z, Caron MG, Blakely RD, Margolis KG, Gershon MD
(2010) J Neurosci 30: 16730-40 - Synergistic effect of norepinephrine transporter blockade and α-2 antagonism on blood pressure in autonomic failure.
Okamoto LE, Shibao C, Gamboa A, Choi L, Diedrich A, Raj SR, Black BK, Robertson D, Biaggioni I
(2012) Hypertension 59: 650-6 - Norepinephrine transporter blockade with atomoxetine induces hypertension in patients with impaired autonomic function.
Shibao C, Raj SR, Gamboa A, Diedrich A, Choi L, Black BK, Robertson D, Biaggioni I
(2007) Hypertension 50: 47-53 - The norepinephrine transporter inhibitor reboxetine reduces stimulant effects of MDMA ("ecstasy") in humans.
Hysek CM, Simmler LD, Ineichen M, Grouzmann E, Hoener MC, Brenneisen R, Huwyler J, Liechti ME
(2011) Clin Pharmacol Ther 90: 246-55 - Norepinephrine transporter function and autonomic control of metabolism.
Boschmann M, Schroeder C, Christensen NJ, Tank J, Krupp G, Biaggioni I, Klaus S, Sharma AM, Luft FC, Jordan J
(2002) J Clin Endocrinol Metab 87: 5130-7 - Human norepinephrine transporter kinetics using rotating disk electrode voltammetry.
Burnette WB, Bailey MD, Kukoyi S, Blakely RD, Trowbridge CG, Justice JB
(1996) Anal Chem 68: 2932-8 - Chronic desipramine treatment alters tyrosine hydroxylase but not norepinephrine transporter immunoreactivity in norepinephrine axons in the rat prefrontal cortex.
Erickson SL, Gandhi AR, Asafu-Adjei JK, Sampson AR, Miner L, Blakely RD, Sesack SR
(2011) Int J Neuropsychopharmacol 14: 1219-32 - A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters.
Robertson SD, Matthies HJ, Galli A
(2009) Mol Neurobiol 39: 73-80 - Norepinephrine transporter variant A457P knock-in mice display key features of human postural orthostatic tachycardia syndrome.
Shirey-Rice JK, Klar R, Fentress HM, Redmon SN, Sabb TR, Krueger JJ, Wallace NM, Appalsamy M, Finney C, Lonce S, Diedrich A, Hahn MK
(2013) Dis Model Mech 6: 1001-11 - Extracellular norepinephrine clearance by the norepinephrine transporter is required for skeletal homeostasis.
Ma Y, Krueger JJ, Redmon SN, Uppuganti S, Nyman JS, Hahn MK, Elefteriou F
(2013) J Biol Chem 288: 30105-13 - Cell-specific sorting of biogenic amine transporters expressed in epithelial cells.
Gu HH, Ahn J, Caplan MJ, Blakely RD, Levey AI, Rudnick G
(1996) J Biol Chem 271: 18100-6 - Human norepinephrine transporter. Biosynthetic studies using a site-directed polyclonal antibody.
Melikian HE, McDonald JK, Gu H, Rudnick G, Moore KR, Blakely RD
(1994) J Biol Chem 269: 12290-7 - Single nucleotide polymorphisms in the human norepinephrine transporter gene affect expression, trafficking, antidepressant interaction, and protein kinase C regulation.
Hahn MK, Mazei-Robison MS, Blakely RD
(2005) Mol Pharmacol 68: 457-66 - Amphetamine induces a calcium/calmodulin-dependent protein kinase II-dependent reduction in norepinephrine transporter surface expression linked to changes in syntaxin 1A/transporter complexes.
Dipace C, Sung U, Binda F, Blakely RD, Galli A
(2007) Mol Pharmacol 71: 230-9 - Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter.
Barker EL, Blakely RD
(1996) Mol Pharmacol 50: 957-65 - Inability to N-glycosylate the human norepinephrine transporter reduces protein stability, surface trafficking, and transport activity but not ligand recognition.
Melikian HE, Ramamoorthy S, Tate CG, Blakely RD
(1996) Mol Pharmacol 50: 266-76 - Functional gene variation in the human norepinephrine transporter: association with attention deficit hyperactivity disorder.
Kim CH, Waldman ID, Blakely RD, Kim KS
(2008) Ann N Y Acad Sci 1129: 256-60 - Genetic basis of clinical catecholamine disorders.
Garland EM, Hahn MK, Ketch TP, Keller NR, Kim CH, Kim KS, Biaggioni I, Shannon JR, Blakely RD, Robertson D
(2002) Ann N Y Acad Sci 971: 506-14 - Familial orthostatic tachycardia due to norepinephrine transporter deficiency.
Robertson D, Flattem N, Tellioglu T, Carson R, Garland E, Shannon JR, Jordan J, Jacob G, Blakely RD, Biaggioni I
(2001) Ann N Y Acad Sci 940: 527-43 - Novel and functional norepinephrine transporter protein variants identified in attention-deficit hyperactivity disorder.
Hahn MK, Steele A, Couch RS, Stein MA, Krueger JJ
(2009) Neuropharmacology 57: 694-701 - The N-terminus of the norepinephrine transporter regulates the magnitude and selectivity of the transporter-associated leak current.
Binda F, Lute BJ, Dipace C, Blakely RD, Galli A
(2006) Neuropharmacology 50: 354-61 - Down-regulation of the human norepinephrine transporter in intact 293-hNET cells exposed to desipramine.
Zhu MY, Blakely RD, Apparsundaram S, Ordway GA
(1998) J Neurochem 70: 1547-55
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