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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Publications
- Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide.
Myers PR, Minor RL, Guerra R, Bates JN, Harrison DG
(1990) Nature 345: 161-3 - NMR structure and mutagenesis of the FADD (Mort1) death-effector domain.
Eberstadt M, Huang B, Chen Z, Meadows RP, Ng SC, Zheng L, Lenardo MJ, Fesik SW
(1998) Nature 392: 941-5 - Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain.
Liu Z, Sun C, Olejniczak ET, Meadows RP, Betz SF, Oost T, Herrmann J, Wu JC, Fesik SW
(2000) Nature 408: 1004-8 - Structural biology. Controlling the caspases.
Fesik SW, Shi Y
(2001) Science 294: 1477-8 - Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome.
Verma R, Aravind L, Oania R, McDonald WH, Yates JR, Koonin EV, Deshaies RJ
(2002) Science 298: 611-5 - Regulation of transcriptional activation domain function by ubiquitin.
Salghetti SE, Caudy AA, Chenoweth JG, Tansey WP
(2001) Science 293: 1651-3 - Transcriptional regulation: RUPture in the ER.
Tansey WP
(2000) Nat Cell Biol 2: E175-7 - Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain.
Flick K, Ouni I, Wohlschlegel JA, Capati C, McDonald WH, Yates JR, Kaiser P
(2004) Nat Cell Biol 6: 634-41 - Altered peptidase and viral-specific T cell response in LMP2 mutant mice.
Van Kaer L, Ashton-Rickardt PG, Eichelberger M, Gaczynska M, Nagashima K, Rock KL, Goldberg AL, Doherty PC, Tonegawa S
(1994) Immunity 1: 533-41 - Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers.
Vilar M, Charalampopoulos I, Kenchappa RS, Simi A, Karaca E, Reversi A, Choi S, Bothwell M, Mingarro I, Friedman WJ, Schiavo G, Bastiaens PI, Verveer PJ, Carter BD, Ibáñez CF
(2009) Neuron 62: 72-83 - Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3.
Ezhkova E, Tansey WP
(2004) Mol Cell 13: 435-42 - Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication.
Méndez J, Zou-Yang XH, Kim SY, Hidaka M, Tansey WP, Stillman B
(2002) Mol Cell 9: 481-91 - Mechanisms of interaction between the sulfhydryl precursor L-methionine and glyceryl trinitrate.
Münzel T, Mülsch A, Holtz J, Just H, Harrison DG, Bassenge E
(1992) Circulation 86: 995-1003 - Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.
Kumari M, Schoiswohl G, Chitraju C, Paar M, Cornaciu I, Rangrez AY, Wongsiriroj N, Nagy HM, Ivanova PT, Scott SA, Knittelfelder O, Rechberger GN, Birner-Gruenberger R, Eder S, Brown HA, Haemmerle G, Oberer M, Lass A, Kershaw EE, Zimmermann R, Zechner R
(2012) Cell Metab 15: 691-702 - Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits.
Griffin TA, Nandi D, Cruz M, Fehling HJ, Kaer LV, Monaco JJ, Colbert RA
(1998) J Exp Med 187: 97-104 - Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway.
Dai Z, Quackenbush RC, Courtney KD, Grove M, Cortez D, Reuther GW, Pendergast AM
(1998) Genes Dev 12: 1415-24 - Mechanisms responsible for the heterogeneous coronary microvascular response to nitroglycerin.
Kurz MA, Lamping KG, Bates JN, Eastham CL, Marcus ML, Harrison DG
(1991) Circ Res 68: 847-55 - Kinesin-5 inhibitor resistance is driven by kinesin-12.
Sturgill EG, Norris SR, Guo Y, Ohi R
(2016) J Cell Biol 213: 213-27 - Regulation of beta cell glucokinase by S-nitrosylation and association with nitric oxide synthase.
Rizzo MA, Piston DW
(2003) J Cell Biol 161: 243-8 - Site-specific mapping and quantification of protein S-sulphenylation in cells.
Yang J, Gupta V, Carroll KS, Liebler DC
(2014) Nat Commun 5: 4776 - Natural killer T cell-a cat o' nine lives!
Joyce S, Gordy LE
(2010) EMBO J 29: 1475-6 - Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex.
Matsuura H, Kirschner AN, Longnecker R, Jardetzky TS
(2010) Proc Natl Acad Sci U S A 107: 22641-6 - Differential interaction of spin-labeled arrestin with inactive and active phosphorhodopsin.
Hanson SM, Francis DJ, Vishnivetskiy SA, Kolobova EA, Hubbell WL, Klug CS, Gurevich VV
(2006) Proc Natl Acad Sci U S A 103: 4900-5 - Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice.
Lenferink AE, Simpson JF, Shawver LK, Coffey RJ, Forbes JT, Arteaga CL
(2000) Proc Natl Acad Sci U S A 97: 9609-14 - Identification of S-nitrosylation motifs by site-specific mapping of the S-nitrosocysteine proteome in human vascular smooth muscle cells.
Greco TM, Hodara R, Parastatidis I, Heijnen HF, Dennehy MK, Liebler DC, Ischiropoulos H
(2006) Proc Natl Acad Sci U S A 103: 7420-5 - Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions.
Eischen CM, Kottke TJ, Martins LM, Basi GS, Tung JS, Earnshaw WC, Leibson PJ, Kaufmann SH
(1997) Blood 90: 935-43 - Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells.
Fonteneau JF, Kavanagh DG, Lirvall M, Sanders C, Cover TL, Bhardwaj N, Larsson M
(2003) Blood 102: 4448-55 - Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes.
Laidlaw TM, Kidder MS, Bhattacharyya N, Xing W, Shen S, Milne GL, Castells MC, Chhay H, Boyce JA
(2012) Blood 119: 3790-8 - NADPH oxidase activity is essential for Keap1/Nrf2-mediated induction of GCLC in response to 2-indol-3-yl-methylenequinuclidin-3-ols.
Sekhar KR, Crooks PA, Sonar VN, Friedman DB, Chan JY, Meredith MJ, Starnes JH, Kelton KR, Summar SR, Sasi S, Freeman ML
(2003) Cancer Res 63: 5636-45 - Failure of chronic glutathione elevation to reduce cytotoxicity produced by exposure to cis-diamminedichloroplatinum(II), ionizing radiation, or hyperthermia.
Freeman ML, Meredith MJ, Eisert DR
(1990) Cancer Res 50: 5296-300 - Calpains play a role in insulin secretion and action.
Sreenan SK, Zhou YP, Otani K, Hansen PA, Currie KP, Pan CY, Lee JP, Ostrega DM, Pugh W, Horikawa Y, Cox NJ, Hanis CL, Burant CF, Fox AP, Bell GI, Polonsky KS
(2001) Diabetes 50: 2013-20 - B-Myc is preferentially expressed in hormonally-controlled tissues and inhibits cellular proliferation.
Gregory MA, Xiao Q, Cornwall GA, Lutterbach B, Hann SR
(2000) Oncogene 19: 4886-95 - Multiple cell-type-specific elements regulate Myc protein stability.
Herbst A, Salghetti SE, Kim SY, Tansey WP
(2004) Oncogene 23: 3863-71 - Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2.
Sekhar KR, Yan XX, Freeman ML
(2002) Oncogene 21: 6829-34 - Sulfenylation of Human Liver and Kidney Microsomal Cytochromes P450 and Other Drug-Metabolizing Enzymes as a Response to Redox Alteration.
Albertolle ME, Phan TTN, Pozzi A, Guengerich FP
(2018) Mol Cell Proteomics 17: 889-900 - Endothelial NO synthase polymorphisms and postural tachycardia syndrome.
Garland EM, Winker R, Williams SM, Jiang L, Stanton K, Byrne DW, Biaggioni I, Cascorbi I, Phillips JA, Harris PA, Rüdiger H, Robertson D
(2005) Hypertension 46: 1103-10 - EDRF: nitrosylated compound or authentic nitric oxide.
Bates JN, Harrison DG, Myers PR, Minor RL
(1991) Basic Res Cardiol 86 Suppl 2: 17-26 - Regulation of focal complex composition and disassembly by the calcium-dependent protease calpain.
Bhatt A, Kaverina I, Otey C, Huttenlocher A
(2002) J Cell Sci 115: 3415-25 - A trial of antioxidants N-acetylcysteine and procysteine in ARDS. The Antioxidant in ARDS Study Group.
Bernard GR, Wheeler AP, Arons MM, Morris PE, Paz HL, Russell JA, Wright PE
(1997) Chest 112: 164-72 - Nuclear and cytoplasmic degradation of endogenous p53 and HDM2 occurs during down-regulation of the p53 response after multiple types of DNA damage.
Joseph TW, Zaika A, Moll UM
(2003) FASEB J 17: 1622-30
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