Regulation of Selenium Metabolism and Transport. Burk RF, Hill KE (2015) Annu Rev Nutr 35: 109-34 Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor. Gaultier A, Arandjelovic S, Niessen S, Overton CD, Linton MF, Fazio S, Campana WM, Cravatt BF, Gonias SL (2008) Blood 111: 5316-25 Deletion of apolipoprotein E receptor-2 in mice lowers brain selenium and causes severe neurological dysfunction and death when a low-selenium diet is fed. Burk RF, Hill KE, Olson GE, Weeber EJ, Motley AK, Winfrey VP, Austin LM (2007) J Neurosci 27: 6207-11 Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2). White-Adams TC, Berny MA, Tucker EI, Gertz JM, Gailani D, Urbanus RT, de Groot PG, Gruber A, McCarty OJ (2009) Arterioscler Thromb Vasc Biol 29: 1602-7 A p120-catenin-CK1epsilon complex regulates Wnt signaling. Casagolda D, Del Valle-Pérez B, Valls G, Lugilde E, Vinyoles M, Casado-Vela J, Solanas G, Batlle E, Reynolds AB, Casal JI, de Herreros AG, Duñach M (2010) J Cell Sci 123: 2621-31 Maternal-fetal transfer of selenium in the mouse. Burk RF, Olson GE, Hill KE, Winfrey VP, Motley AK, Kurokawa S (2013) FASEB J 27: 3249-56 Selenoprotein P and apolipoprotein E receptor-2 interact at the blood-brain barrier and also within the brain to maintain an essential selenium pool that protects against neurodegeneration. Burk RF, Hill KE, Motley AK, Winfrey VP, Kurokawa S, Mitchell SL, Zhang W (2014) FASEB J 28: 3579-88 Long isoform mouse selenoprotein P (Sepp1) supplies rat myoblast L8 cells with selenium via endocytosis mediated by heparin binding properties and apolipoprotein E receptor-2 (ApoER2). Kurokawa S, Hill KE, McDonald WH, Burk RF (2012) J Biol Chem 287: 28717-26 Neurodegeneration in mice resulting from loss of functional selenoprotein P or its receptor apolipoprotein E receptor 2. Valentine WM, Abel TW, Hill KE, Austin LM, Burk RF (2008) J Neuropathol Exp Neurol 67: 68-77
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