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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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- Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency.
Shannon JR, Flattem NL, Jordan J, Jacob G, Black BK, Biaggioni I, Blakely RD, Robertson D
(2000) N Engl J Med 342: 541-9 - Hemodynamic and humoral effects of caffeine in autonomic failure. Therapeutic implications for postprandial hypotension.
Onrot J, Goldberg MR, Biaggioni I, Hollister AS, Kingaid D, Robertson D
(1985) N Engl J Med 313: 549-54 - The neuropathic postural tachycardia syndrome.
Jacob G, Costa F, Shannon JR, Robertson RM, Wathen M, Stein M, Biaggioni I, Ertl A, Black B, Robertson D
(2000) N Engl J Med 343: 1008-14 - A rare variant in MYH6 is associated with high risk of sick sinus syndrome.
Holm H, Gudbjartsson DF, Sulem P, Masson G, Helgadottir HT, Zanon C, Magnusson OT, Helgason A, Saemundsdottir J, Gylfason A, Stefansdottir H, Gretarsdottir S, Matthiasson SE, Thorgeirsson GM, Jonasdottir A, Sigurdsson A, Stefansson H, Werge T, Rafnar T, Kiemeney LA, Parvez B, Muhammad R, Roden DM, Darbar D, Thorleifsson G, Walters GB, Kong A, Thorsteinsdottir U, Arnar DO, Stefansson K
(2011) Nat Genet 43: 316-20 - Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans.
Watanabe H, Chopra N, Laver D, Hwang HS, Davies SS, Roach DE, Duff HJ, Roden DM, Wilde AA, Knollmann BC
(2009) Nat Med 15: 380-3 - Blockade of nucleoside transport is required for delivery of intraarterial adenosine into the interstitium: relevance to therapeutic preconditioning in humans.
Gamboa A, Ertl AC, Costa F, Farley G, Manier ML, Hachey DL, Diedrich A, Biaggioni I
(2003) Circulation 108: 2631-5 - Nitroglycerin induces late preconditioning against myocardial infarction in conscious rabbits despite development of nitrate tolerance.
Hill M, Takano H, Tang XL, Kodani E, Shirk G, Bolli R
(2001) Circulation 104: 694-9 - Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles.
Vincent S, Bieck PR, Garland EM, Loghin C, Bymaster FP, Black BK, Gonzales C, Potter WZ, Robertson D
(2004) Circulation 109: 3202-7 - The effect of hypertension and left ventricular hypertrophy on the lower range of coronary autoregulation.
Harrison DG, Florentine MS, Brooks LA, Cooper SM, Marcus ML
(1988) Circulation 77: 1108-15 - Modulation of QT interval during autonomic nervous system blockade in humans.
Diedrich A, Jordan J, Shannon JR, Robertson D, Biaggioni I
(2002) Circulation 106: 2238-43 - Neurovascular dissociation with paradoxical forearm vasodilation during systemic tyramine administration.
Jacob G, Costa F, Vincent S, Robertson D, Biaggioni I
(2003) Circulation 107: 2475-9 - Classification and Reporting of Potentially Proarrhythmic Common Genetic Variation in Long QT Syndrome Genetic Testing.
Giudicessi JR, Roden DM, Wilde AAM, Ackerman MJ
(2018) Circulation 137: 619-630 - Four faces of baroreflex failure: hypertensive crisis, volatile hypertension, orthostatic tachycardia, and malignant vagotonia.
Ketch T, Biaggioni I, Robertson R, Robertson D
(2002) Circulation 105: 2518-23 - Selective norepinephrine reuptake inhibition as a human model of orthostatic intolerance.
Schroeder C, Tank J, Boschmann M, Diedrich A, Sharma AM, Biaggioni I, Luft FC, Jordan J
(2002) Circulation 105: 347-53 - Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk.
Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosley JD, Pulley JM, Basford MA, Bradford Y, Rasmussen LV, Pathak J, Chute CG, Kullo IJ, McCarty CA, Chisholm RL, Kho AN, Carlson CS, Larson EB, Jarvik GP, Sotoodehnia N, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) QRS Group, Manolio TA, Li R, Masys DR, Haines JL, Roden DM
(2013) Circulation 127: 1377-85 - The use of radionuclide angiography in the diagnosis of coronary artery disease--a logistic regression analysis.
Gibbons RJ, Lee KL, Pryor D, Harrell FE, Coleman RE, Cobb FR, Rosati RA, Jones RH
(1983) Circulation 68: 740-6 - Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation.
Drew BJ, Ackerman MJ, Funk M, Gibler WB, Kligfield P, Menon V, Philippides GJ, Roden DM, Zareba W, American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology, the Council on Cardiovascular Nursing, and the American College of Cardiology Foundation
(2010) Circulation 121: 1047-60 - Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more.
Raj SR, Black BK, Biaggioni I, Paranjape SY, Ramirez M, Dupont WD, Robertson D
(2009) Circulation 120: 725-34 - Ibrutinib-Mediated Atrial Fibrillation Attributable to Inhibition of C-Terminal Src Kinase.
Xiao L, Salem JE, Clauss S, Hanley A, Bapat A, Hulsmans M, Iwamoto Y, Wojtkiewicz G, Cetinbas M, Schloss MJ, Tedeschi J, Lebrun-Vignes B, Lundby A, Sadreyev RI, Moslehi J, Nahrendorf M, Ellinor PT, Milan DJ
(2020) Circulation 142: 2443-2455 - Hypogonadism as a Reversible Cause of Torsades de Pointes in Men.
Salem JE, Waintraub X, Courtillot C, Shaffer CM, Gandjbakhch E, Maupain C, Moslehi JJ, Badilini F, Haroche J, Gougis P, Fressart V, Glazer AM, Hidden-Lucet F, Touraine P, Lebrun-Vignes B, Roden DM, Bachelot A, Funck-Brentano C
(2018) Circulation 138: 110-113 - Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome.
Raj SR, Black BK, Biaggioni I, Harris PA, Robertson D
(2005) Circulation 111: 2734-40 - Baroreflex buffering and susceptibility to vasoactive drugs.
Jordan J, Tank J, Shannon JR, Diedrich A, Lipp A, Schröder C, Arnold G, Sharma AM, Biaggioni I, Robertson D, Luft FC
(2002) Circulation 105: 1459-64 - Water ingestion as prophylaxis against syncope.
Lu CC, Diedrich A, Tung CS, Paranjape SY, Harris PA, Byrne DW, Jordan J, Robertson D
(2003) Circulation 108: 2660-5 - Effects of volume loading and pressor agents in idiopathic orthostatic tachycardia.
Jacob G, Shannon JR, Black B, Biaggioni I, Mosqueda-Garcia R, Robertson RM, Robertson D
(1997) Circulation 96: 575-80 - Paradoxical effect of sibutramine on autonomic cardiovascular regulation.
Birkenfeld AL, Schroeder C, Boschmann M, Tank J, Franke G, Luft FC, Biaggioni I, Sharma AM, Jordan J
(2002) Circulation 106: 2459-65 - Sympathetically mediated hypertension in autonomic failure.
Shannon JR, Jordan J, Diedrich A, Pohar B, Black BK, Robertson D, Biaggioni I
(2000) Circulation 101: 2710-5 - Heritability, linkage, and genetic associations of exercise treadmill test responses.
Ingelsson E, Larson MG, Vasan RS, O'Donnell CJ, Yin X, Hirschhorn JN, Newton-Cheh C, Drake JA, Musone SL, Heard-Costa NL, Benjamin EJ, Levy D, Atwood LD, Wang TJ, Kathiresan S
(2007) Circulation 115: 2917-24 - A common β1-adrenergic receptor polymorphism predicts favorable response to rate-control therapy in atrial fibrillation.
Parvez B, Chopra N, Rowan S, Vaglio JC, Muhammad R, Roden DM, Darbar D
(2012) J Am Coll Cardiol 59: 49-56 - Hemodynamic, ventilatory, and biochemical responses of panic patients and normal controls with sodium lactate infusion and spontaneous panic attacks.
Gaffney FA, Fenton BJ, Lane LD, Lake CR
(1988) Arch Gen Psychiatry 45: 53-60 - Suppression of ventricular arrhythmias in man by d-propranolol independent of beta-adrenergic receptor blockade.
Murray KT, Reilly C, Koshakji RP, Roden DM, Lineberry MD, Wood AJ, Siddoway LA, Barbey JT, Woosley RL
(1990) J Clin Invest 85: 836-42 - Diabetes increases mortality after myocardial infarction by oxidizing CaMKII.
Luo M, Guan X, Luczak ED, Lang D, Kutschke W, Gao Z, Yang J, Glynn P, Sossalla S, Swaminathan PD, Weiss RM, Yang B, Rokita AG, Maier LS, Efimov IR, Hund TJ, Anderson ME
(2013) J Clin Invest 123: 1262-74 - Comparison of the direct and indirect effects of epinephrine on hepatic glucose production.
Chu CA, Sindelar DK, Neal DW, Allen EJ, Donahue EP, Cherrington AD
(1997) J Clin Invest 99: 1044-56 - Cardiovascular and respiratory effects of adenosine in conscious man. Evidence for chemoreceptor activation.
Biaggioni I, Olafsson B, Robertson RM, Hollister AS, Robertson D
(1987) Circ Res 61: 779-86 - Adrenergic coronary tone during submaximal exercise in the dog is produced by circulating catecholamines. Evidence for adrenergic denervation supersensitivity in the myocardium but not in coronary vessels.
Chilian WM, Harrison DG, Haws CW, Snyder WD, Marcus ML
(1986) Circ Res 58: 68-82 - RGS6, a modulator of parasympathetic activation in heart.
Yang J, Huang J, Maity B, Gao Z, Lorca RA, Gudmundsson H, Li J, Stewart A, Swaminathan PD, Ibeawuchi SR, Shepherd A, Chen CK, Kutschke W, Mohler PJ, Mohapatra DP, Anderson ME, Fisher RA
(2010) Circ Res 107: 1345-9 - Very-long-chain acyl-coenzyme a dehydrogenase deficiency in mice.
Exil VJ, Roberts RL, Sims H, McLaughlin JE, Malkin RA, Gardner CD, Ni G, Rottman JN, Strauss AW
(2003) Circ Res 93: 448-55 - RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT.
Kryshtal DO, Blackwell DJ, Egly CL, Smith AN, Batiste SM, Johnston JN, Laver DR, Knollmann BC
(2021) Circ Res 128: 321-331 - Adenosine produces pulmonary vasoconstriction in sheep. Evidence for thromboxane A2/prostaglandin endoperoxide-receptor activation.
Biaggioni I, King LS, Enayat N, Robertson D, Newman JH
(1989) Circ Res 65: 1516-25 - Cardiovascular effects of neuropeptide Y in rat brainstem nuclei.
Tseng CJ, Mosqueda-Garcia R, Appalsamy M, Robertson D
(1989) Circ Res 64: 55-61 - Combined 1H and 31P nuclear magnetic resonance spectroscopic studies of bicuculline-induced seizures in vivo.
Petroff OA, Prichard JW, Ogino T, Avison M, Alger JR, Shulman RG
(1986) Ann Neurol 20: 185-93
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