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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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- Rational use of analgesic and antiinflammatory drugs.
Crofford LJ
(2001) N Engl J Med 345: 1844-6 - Clinical implications of prostaglandin and thromboxane A2 formation (2).
Oates JA, FitzGerald GA, Branch RA, Jackson EK, Knapp HR, Roberts LJ
(1988) N Engl J Med 319: 761-7 - Effect of a prior-authorization requirement on the use of nonsteroidal antiinflammatory drugs by Medicaid patients.
Smalley WE, Griffin MR, Fought RL, Sullivan L, Ray WA
(1995) N Engl J Med 332: 1612-7 - Clinical implications of prostaglandin and thromboxane A2 formation (1).
Oates JA, FitzGerald GA, Branch RA, Jackson EK, Knapp HR, Roberts LJ
(1988) N Engl J Med 319: 689-98 - Efficacy and safety of recombinant human activated protein C for severe sepsis.
Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ, Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group
(2001) N Engl J Med 344: 699-709 - COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease.
Ray WA, Stein CM, Daugherty JR, Hall K, Arbogast PG, Griffin MR
(2002) Lancet 360: 1071-3 - High-dose non-steroidal anti-inflammatories: painful choices.
Griffin MR
(2013) Lancet 382: 746-8 - Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease: an observational cohort study.
Ray WA, Stein CM, Hall K, Daugherty JR, Griffin MR
(2002) Lancet 359: 118-23 - Differential stem- and progenitor-cell trafficking by prostaglandin E2.
Hoggatt J, Mohammad KS, Singh P, Hoggatt AF, Chitteti BR, Speth JM, Hu P, Poteat BA, Stilger KN, Ferraro F, Silberstein L, Wong FK, Farag SS, Czader M, Milne GL, Breyer RM, Serezani CH, Scadden DT, Guise TA, Srour EF, Pelus LM
(2013) Nature 495: 365-9 - A rising StAR: an essential role in cholesterol transport.
Waterman MR
(1995) Science 267: 1780-1 - Aspirin-like molecules that covalently inactivate cyclooxygenase-2.
Kalgutkar AS, Crews BC, Rowlinson SW, Garner C, Seibert K, Marnett LJ
(1998) Science 280: 1268-70 - Expression of bovine 17 alpha-hydroxylase cytochrome P-450 cDNA in nonsteroidogenic (COS 1) cells.
Zuber MX, Simpson ER, Waterman MR
(1986) Science 234: 1258-61 - Neurosteroids: cytochrome P-450scc in rat brain.
Le Goascogne C, Robel P, Gouézou M, Sananès N, Baulieu EE, Waterman M
(1987) Science 237: 1212-5 - Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes.
Levin GP, Robinson-Cohen C, de Boer IH, Houston DK, Lohman K, Liu Y, Kritchevsky SB, Cauley JA, Tanaka T, Ferrucci L, Bandinelli S, Patel KV, Hagström E, Michaëlsson K, Melhus H, Wang T, Wolf M, Psaty BM, Siscovick D, Kestenbaum B
(2012) JAMA 308: 1898-905 - The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, Gonzalez FJ, Schuetz EG, Kim RB
(2003) Nat Med 9: 220-4 - The COXIB experience: a look in the rearview mirror.
Marnett LJ
(2009) Annu Rev Pharmacol Toxicol 49: 265-90 - COX-2: a target for colon cancer prevention.
Marnett LJ, DuBois RN
(2002) Annu Rev Pharmacol Toxicol 42: 55-80 - 17 alpha-hydroxylase/17,20-lyase deficiency: from clinical investigation to molecular definition.
Yanase T, Simpson ER, Waterman MR
(1991) Endocr Rev 12: 91-108 - Response.
Sahasrabuddhe VV, Gunja MZ, Graubard BI, Trabert B, Schwartz LM, Park Y, Hollenbeck AR, Freedman ND, McGlynn KA
(2013) J Natl Cancer Inst 105: 668- 71 - Nonsteroidal anti-inflammatory drug use, chronic liver disease, and hepatocellular carcinoma.
Sahasrabuddhe VV, Gunja MZ, Graubard BI, Trabert B, Schwartz LM, Park Y, Hollenbeck AR, Freedman ND, McGlynn KA
(2012) J Natl Cancer Inst 104: 1808-14 - Nonsteroidal anti-inflammatory drug use and death from peptic ulcer in elderly persons.
Griffin MR, Ray WA, Schaffner W
(1988) Ann Intern Med 109: 359-63 - Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons.
Griffin MR, Piper JM, Daugherty JR, Snowden M, Ray WA
(1991) Ann Intern Med 114: 257-63 - Corticosteroid use and peptic ulcer disease: role of nonsteroidal anti-inflammatory drugs.
Piper JM, Ray WA, Daugherty JR, Griffin MR
(1991) Ann Intern Med 114: 735-40 - Risk of peptic ulcer hospitalizations in users of NSAIDs with gastroprotective cotherapy versus coxibs.
Ray WA, Chung CP, Stein CM, Smalley WE, Hall K, Arbogast PG, Griffin MR
(2007) Gastroenterology 133: 790-8 - Elimination of Helicobacter pylori or acid in high-risk users of aspirin or nonsteroidal medications: final answer?
Peek RM
(2002) Gastroenterology 122: 238-40 - Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.
Zeng C, Matsuda K, Jia WH, Chang J, Kweon SS, Xiang YB, Shin A, Jee SH, Kim DH, Zhang B, Cai Q, Guo X, Long J, Wang N, Courtney R, Pan ZZ, Wu C, Takahashi A, Shin MH, Matsuo K, Matsuda F, Gao YT, Oh JH, Kim S, Jung KJ, Ahn YO, Ren Z, Li HL, Wu J, Shi J, Wen W, Yang G, Li B, Ji BT, Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO), Brenner H, Schoen RE, Küry S, Colorectal Transdisciplinary (CORECT) Study, Gruber SB, Schumacher FR, Stenzel SL, Colon Cancer Family Registry (CCFR), Casey G, Hopper JL, Jenkins MA, Kim HR, Jeong JY, Park JW, Tajima K, Cho SH, Kubo M, Shu XO, Lin D, Zeng YX, Zheng W
(2016) Gastroenterology 150: 1633-1645 - Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori.
Atherton JC, Peek RM, Tham KT, Cover TL, Blaser MJ
(1997) Gastroenterology 112: 92-9 - Increased gastroduodenal concentrations of transforming growth factor alpha in adaptation to aspirin in monkeys and rats.
Romano M, Lesch CA, Meise KS, Veljaca M, Sanchez B, Kraus ER, Boland CR, Guglietta A, Coffey RJ
(1996) Gastroenterology 110: 1448-55 - Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II.
Qi Z, Hao CM, Langenbach RI, Breyer RM, Redha R, Morrow JD, Breyer MD
(2002) J Clin Invest 110: 61-9 - Aspirin use and potential mechanisms for colorectal cancer prevention.
Williams CS, Smalley W, DuBois RN
(1997) J Clin Invest 100: 1325-9 - Discontinuing nasal steroids might lower intraocular pressure in glaucoma.
Bui CM, Chen H, Shyr Y, Joos KM
(2005) J Allergy Clin Immunol 116: 1042-7 - The genetics of pulmonary arterial hypertension.
Austin ED, Loyd JE
(2014) Circ Res 115: 189-202 - Rational design of diflunisal analogues with reduced affinity for human serum albumin.
Mao H, Hajduk PJ, Craig R, Bell R, Borre T, Fesik SW
(2001) J Am Chem Soc 123: 10429-35 - Cytochromes P450 in synthesis of steroid hormones, bile acids, vitamin D3 and cholesterol.
Pikuleva I, Waterman M
(1999) Mol Aspects Med 20: 33-42, 43-37 - Structure of the heterodimeric ecdysone receptor DNA-binding complex.
Devarakonda S, Harp JM, Kim Y, Ozyhar A, Rastinejad F
(2003) EMBO J 22: 5827-40 - pipsqueak encodes a novel nuclear protein required downstream of seven-up for the development of photoreceptors R3 and R4.
Weber U, Siegel V, Mlodzik M
(1995) EMBO J 14: 6247-57 - Transcriptional regulation of steroid hydroxylase genes by corticotropin.
John ME, John MC, Boggaram V, Simpson ER, Waterman MR
(1986) Proc Natl Acad Sci U S A 83: 4715-9 - Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli.
Barnes HJ, Arlotto MP, Waterman MR
(1991) Proc Natl Acad Sci U S A 88: 5597-601 - Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors.
Kalgutkar AS, Crews BC, Rowlinson SW, Marnett AB, Kozak KR, Remmel RP, Marnett LJ
(2000) Proc Natl Acad Sci U S A 97: 925-30
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