Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen. Pishchany G, Mevers E, Ndousse-Fetter S, Horvath DJ, Paludo CR, Silva-Junior EA, Koren S, Skaar EP, Clardy J, Kolter R (2018) Proc Natl Acad Sci U S A 115: 10124-10129 Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells. Liu Y, Li PK, Li C, Lin J (2010) J Biol Chem 285: 27429-27439 A phase II trial of piroxantrone in disseminated malignant melanoma. A Southwest Oncology Group study. Sosman JA, Flaherty LE, Liu PY, Fletcher W, Thompson JA, Hantel A, Sondak V (1995) Invest New Drugs 13: 83-7 Cytochrome P450 2S1 is reduced by NADPH-cytochrome P450 reductase. Xiao Y, Shinkyo R, Guengerich FP (2011) Drug Metab Dispos 39: 944-6 LLL12 inhibits endogenous and exogenous interleukin-6-induced STAT3 phosphorylation in human pancreatic cancer cells. Liu A, Liu Y, Li PK, Li C, Lin J (2011) Anticancer Res 31: 2029-35
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