The ADP ribosylation factor nucleotide exchange factor ARNO promotes beta-arrestin release necessary for luteinizing hormone/choriogonadotropin receptor desensitization. Mukherjee S, Gurevich VV, Jones JC, Casanova JE, Frank SR, Maizels ET, Bader MF, Kahn RA, Palczewski K, Aktories K, Hunzicker-Dunn M (2000) Proc Natl Acad Sci U S A 97: 5901-6 Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice. Morgan JA, Cheepala SB, Wang Y, Neale G, Adachi M, Nachagari D, Leggas M, Zhao W, Boyd K, Venkataramanan R, Schuetz JD (2012) J Biol Chem 287: 14456-66 beta-arrestin-dependent desensitization of luteinizing hormone/choriogonadotropin receptor is prevented by a synthetic peptide corresponding to the third intracellular loop of the receptor. Mukherjee S, Palczewski K, Gurevich VV, Hunzicker-Dunn M (1999) J Biol Chem 274: 12984-9 Aspartic acid 564 in the third cytoplasmic loop of the luteinizing hormone/choriogonadotropin receptor is crucial for phosphorylation-independent interaction with arrestin2. Mukherjee S, Gurevich VV, Preninger A, Hamm HE, Bader MF, Fazleabas AT, Birnbaumer L, Hunzicker-Dunn M (2002) J Biol Chem 277: 17916-27 ARF6: a newly appreciated player in G protein-coupled receptor desensitization. Hunzicker-Dunn M, Gurevich VV, Casanova JE, Mukherjee S (2002) FEBS Lett 521: 3-8
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