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Connections to Antigens, Viral are shown below. Double-click or tap a node for more information.
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- Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture.
Ruley HE
(1983) Nature 304: 602-6 - Proof of principle for epitope-focused vaccine design.
Correia BE, Bates JT, Loomis RJ, Baneyx G, Carrico C, Jardine JG, Rupert P, Correnti C, Kalyuzhniy O, Vittal V, Connell MJ, Stevens E, Schroeter A, Chen M, Macpherson S, Serra AM, Adachi Y, Holmes MA, Li Y, Klevit RE, Graham BS, Wyatt RT, Baker D, Strong RK, Crowe JE, Johnson PR, Schief WR
(2014) Nature 507: 201-6 - Evidence for a differential avidity model of T cell selection in the thymus.
Ashton-Rickardt PG, Bandeira A, Delaney JR, Van Kaer L, Pircher HP, Zinkernagel RM, Tonegawa S
(1994) Cell 76: 651-63 - Viral evasion of antigen presentation: not just for peptides anymore.
Van Kaer L, Joyce S
(2006) Nat Immunol 7: 795-7 - Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes.
Monsalvo AC, Batalle JP, Lopez MF, Krause JC, Klemenc J, Hernandez JZ, Maskin B, Bugna J, Rubinstein C, Aguilar L, Dalurzo L, Libster R, Savy V, Baumeister E, Aguilar L, Cabral G, Font J, Solari L, Weller KP, Johnson J, Echavarria M, Edwards KM, Chappell JD, Crowe JE, Williams JV, Melendi GA, Polack FP
(2011) Nat Med 17: 195-9 - Altered peptidase and viral-specific T cell response in LMP2 mutant mice.
Van Kaer L, Ashton-Rickardt PG, Eichelberger M, Gaczynska M, Nagashima K, Rock KL, Goldberg AL, Doherty PC, Tonegawa S
(1994) Immunity 1: 533-41 - Peyer's patch dendritic cells process viral antigen from apoptotic epithelial cells in the intestine of reovirus-infected mice.
Fleeton MN, Contractor N, Leon F, Wetzel JD, Dermody TS, Kelsall BL
(2004) J Exp Med 200: 235-45 - Binding of type 3 reovirus by a domain of the sigma 1 protein important for hemagglutination leads to infection of murine erythroleukemia cells.
Rubin DH, Wetzel JD, Williams WV, Cohen JA, Dworkin C, Dermody TS
(1992) J Clin Invest 90: 2536-42 - Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary disease.
Barton ES, Youree BE, Ebert DH, Forrest JC, Connolly JL, Valyi-Nagy T, Washington K, Wetzel JD, Dermody TS
(2003) J Clin Invest 111: 1823-33 - Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer.
Bierie B, Chung CH, Parker JS, Stover DG, Cheng N, Chytil A, Aakre M, Shyr Y, Moses HL
(2009) J Clin Invest 119: 1571-82 - Viral acute lower respiratory infections impair CD8+ T cells through PD-1.
Erickson JJ, Gilchuk P, Hastings AK, Tollefson SJ, Johnson M, Downing MB, Boyd KL, Johnson JE, Kim AS, Joyce S, Williams JV
(2012) J Clin Invest 122: 2967-82 - Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design.
Crowe JE
(2017) Cell Host Microbe 22: 193-206 - Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum.
Bosch I, de Puig H, Hiley M, Carré-Camps M, Perdomo-Celis F, Narváez CF, Salgado DM, Senthoor D, O'Grady M, Phillips E, Durbin A, Fandos D, Miyazaki H, Yen CW, Gélvez-Ramírez M, Warke RV, Ribeiro LS, Teixeira MM, Almeida RP, Muñóz-Medina JE, Ludert JE, Nogueira ML, Colombo TE, Terzian ACB, Bozza PT, Calheiros AS, Vieira YR, Barbosa-Lima G, Vizzoni A, Cerbino-Neto J, Bozza FA, Souza TML, Trugilho MRO, de Filippis AMB, de Sequeira PC, Marques ETA, Magalhaes T, Díaz FJ, Restrepo BN, Marín K, Mattar S, Olson D, Asturias EJ, Lucera M, Singla M, Medigeshi GR, de Bosch N, Tam J, Gómez-Márquez J, Clavet C, Villar L, Hamad-Schifferli K, Gehrke L
(2017) Sci Transl Med 9: - Vesicular stomatitis virus antigenic octapeptide N52-59 is anchored into the groove of the H-2Kb molecule by the side chains of three amino acids and the main-chain atoms of the amino terminus.
Shibata K, Imarai M, van Bleek GM, Joyce S, Nathenson SG
(1992) Proc Natl Acad Sci U S A 89: 3135-9 - Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene.
Hirakawa T, Ruley HE
(1988) Proc Natl Acad Sci U S A 85: 1519-23 - Prostate cancer in a transgenic mouse.
Greenberg NM, DeMayo F, Finegold MJ, Medina D, Tilley WD, Aspinall JO, Cunha GR, Donjacour AA, Matusik RJ, Rosen JM
(1995) Proc Natl Acad Sci U S A 92: 3439-43 - Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity.
Barbas CF, Crowe JE, Cababa D, Jones TM, Zebedee SL, Murphy BR, Chanock RM, Burton DR
(1992) Proc Natl Acad Sci U S A 89: 10164-8 - Use of a cellular polyadenylation signal by viral transcripts in polyoma virus transformed cells.
Ruley HE, Lania L, Chaudry F, Fried M
(1982) Nucleic Acids Res 10: 4515-24 - Role of c-myc in the transformation of REF52 cells by viral and cellular oncogenes.
Kohl NE, Ruley HE
(1987) Oncogene 2: 41-8 - Expression of Epstein-Barr virus-encoded growth-transformation-associated proteins in lymphoproliferations of bone-marrow transplant recipients.
Gratama JW, Zutter MM, Minarovits J, Oosterveer MA, Thomas ED, Klein G, Ernberg I
(1991) Int J Cancer 47: 188-92 - Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses.
Agnihothram S, Gopal R, Yount BL, Donaldson EF, Menachery VD, Graham RL, Scobey TD, Gralinski LE, Denison MR, Zambon M, Baric RS
(2014) J Infect Dis 209: 995-1006 - Antibody Determinants of Influenza Immunity.
Crowe JE
(2019) J Infect Dis 219: S21-S29 - Human monoclonal antibodies derived from memory B cells following live attenuated dengue virus vaccination or natural infection exhibit similar characteristics.
Smith SA, de Alwis R, Kose N, Durbin AP, Whitehead SS, de Silva AM, Crowe JE
(2013) J Infect Dis 207: 1898-908 - Isolation of a second recombinant human respiratory syncytial virus monoclonal antibody fragment (Fab RSVF2-5) that exhibits therapeutic efficacy in vivo.
Crowe JE, Gilmour PS, Murphy BR, Chanock RM, Duan L, Pomerantz RJ, Pilkington GR
(1998) J Infect Dis 177: 1073-6 - TAP peptide transporter-independent presentation of heat-killed Sendai virus antigen on MHC class I molecules by splenic antigen-presenting cells.
Liu T, Chambers B, Diehl AD, Van Kaer L, Jondal M, Ljunggren HG
(1997) J Immunol 159: 5364-71 - Functional maturation of the human antibody response to rotavirus.
Kallewaard NL, McKinney BA, Gu Y, Chen A, Prasad BV, Crowe JE
(2008) J Immunol 180: 3980-9 - Immunodominance of the VH1-46 antibody gene segment in the primary repertoire of human rotavirus-specific B cells is reduced in the memory compartment through somatic mutation of nondominant clones.
Tian C, Luskin GK, Dischert KM, Higginbotham JN, Shepherd BE, Crowe JE
(2008) J Immunol 180: 3279-88 - Extensive CD4 and CD8 T Cell Cross-Reactivity between Alphaherpesviruses.
Jing L, Laing KJ, Dong L, Russell RM, Barlow RS, Haas JG, Ramchandani MS, Johnston C, Buus S, Redwood AJ, White KD, Mallal SA, Phillips EJ, Posavad CM, Wald A, Koelle DM
(2016) J Immunol 196: 2205-2218 - Influenza Virus-Specific Human Antibody Repertoire Studies.
Crowe JE
(2019) J Immunol 202: 368-373 - Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence.
Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Briney BS, Smith SA, Basler CF, Crowe JE
(2011) J Immunol 187: 3704-11 - Determinants of VH1-46 Cross-Reactivity to Pemphigus Vulgaris Autoantigen Desmoglein 3 and Rotavirus Antigen VP6.
Cho MJ, Ellebrecht CT, Hammers CM, Mukherjee EM, Sapparapu G, Boudreaux CE, McDonald SM, Crowe JE, Payne AS
(2016) J Immunol 197: 1065-73 - Differential regulation of granzyme and perforin in effector and memory T cells following smallpox immunization.
Rock MT, Yoder SM, Wright PF, Talbot TR, Edwards KM, Crowe JE
(2005) J Immunol 174: 3757-64 - Accuracy and interpretation of rapid influenza tests in children.
Grijalva CG, Poehling KA, Edwards KM, Weinberg GA, Staat MA, Iwane MK, Schaffner W, Griffin MR
(2007) Pediatrics 119: e6-11 - Sibling transmission of vaccine-derived rotavirus (RotaTeq) associated with rotavirus gastroenteritis.
Payne DC, Edwards KM, Bowen MD, Keckley E, Peters J, Esona MD, Teel EN, Kent D, Parashar UD, Gentsch JR
(2010) Pediatrics 125: e438-41 - Reovirus-Induced Apoptosis in the Intestine Limits Establishment of Enteric Infection.
Brown JJ, Short SP, Stencel-Baerenwald J, Urbanek K, Pruijssers AJ, McAllister N, Ikizler M, Taylor G, Aravamudhan P, Khomandiak S, Jabri B, Williams CS, Dermody TS
(2018) J Virol 92: - Prolonged replication in the mouse central nervous system of reoviruses isolated from persistently infected cell cultures.
Morrison LA, Fields BN, Dermody TS
(1993) J Virol 67: 3019-26 - Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine.
Benhnia MR, Maybeno M, Blum D, Aguilar-Sino R, Matho M, Meng X, Head S, Felgner PL, Zajonc DM, Koriazova L, Kato S, Burton DR, Xiang Y, Crowe JE, Peters B, Crotty S
(2013) J Virol 87: 1569-85 - Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection.
Lee S, Miller SA, Wright DW, Rock MT, Crowe JE
(2007) J Virol 81: 2349-58
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