Activin- and Nodal-related factors control antero-posterior patterning of the zebrafish embryo. Thisse B, Wright CV, Thisse C (2000) Nature 403: 425-8 Cloning and variation of ground state intestinal stem cells. Wang X, Yamamoto Y, Wilson LH, Zhang T, Howitt BE, Farrow MA, Kern F, Ning G, Hong Y, Khor CC, Chevalier B, Bertrand D, Wu L, Nagarajan N, Sylvester FA, Hyams JS, Devers T, Bronson R, Lacy DB, Ho KY, Crum CP, McKeon F, Xian W (2015) Nature 522: 173-8 Heart repair by reprogramming non-myocytes with cardiac transcription factors. Song K, Nam YJ, Luo X, Qi X, Tan W, Huang GN, Acharya A, Smith CL, Tallquist MD, Neilson EG, Hill JA, Bassel-Duby R, Olson EN (2012) Nature 485: 599-604 Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding. Ito M, Yang Z, Andl T, Cui C, Kim N, Millar SE, Cotsarelis G (2007) Nature 447: 316-20 Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Dor Y, Brown J, Martinez OI, Melton DA (2004) Nature 429: 41-6 The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Kawaguchi Y, Cooper B, Gannon M, Ray M, MacDonald RJ, Wright CV (2002) Nat Genet 32: 128-34 Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling. Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA (2008) Nat Genet 40: 1130-5 A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes. Cree LM, Samuels DC, de Sousa Lopes SC, Rajasimha HK, Wonnapinij P, Mann JR, Dahl HH, Chinnery PF (2008) Nat Genet 40: 249-54 Genetics. My oldest sister is a sea walnut? Rokas A (2013) Science 342: 1327-9 Dynamic changes in histone-methylation 'marks' across the locus encoding interferon-gamma during the differentiation of T helper type 2 cells. Chang S, Aune TM (2007) Nat Immunol 8: 723-31 Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Hodges E, Molaro A, Dos Santos CO, Thekkat P, Song Q, Uren PJ, Park J, Butler J, Rafii S, McCombie WR, Smith AD, Hannon GJ (2011) Mol Cell 44: 17-28 The Promise of Cardiac Regeneration by In Situ Lineage Conversion. Nam YJ, Munshi NV (2017) Circulation 135: 914-916 Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis. Baumgartl J, Baudler S, Scherner M, Babaev V, Makowski L, Suttles J, McDuffie M, Tobe K, Kadowaki T, Fazio S, Kahn CR, Hotamisligil GS, Krone W, Linton M, Brüning JC (2006) Cell Metab 3: 247-56 CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow. Beck TC, Gomes AC, Cyster JG, Pereira JP (2014) J Exp Med 211: 2567-81 Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB. Boothby MR, Mora AL, Scherer DC, Brockman JA, Ballard DW (1997) J Exp Med 185: 1897-907 Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia. Lee K, Nam KT, Cho SH, Gudapati P, Hwang Y, Park DS, Potter R, Chen J, Volanakis E, Boothby M (2012) J Exp Med 209: 713-28 Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development. Moon KH, Kim HT, Lee D, Rao MB, Levine EM, Lim DS, Kim JW (2018) Dev Cell 44: 13-28.e3 Spatial regionalization and heterochrony in the formation of adult pallial neural stem cells. Dirian L, Galant S, Coolen M, Chen W, Bedu S, Houart C, Bally-Cuif L, Foucher I (2014) Dev Cell 30: 123-36 Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G (2019) Dev Cell 48: 49-63.e7 Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes. Al-Hasani K, Pfeifer A, Courtney M, Ben-Othman N, Gjernes E, Vieira A, Druelle N, Avolio F, Ravassard P, Leuckx G, Lacas-Gervais S, Ambrosetti D, Benizri E, Hecksher-Sorensen J, Gounon P, Ferrer J, Gradwohl G, Heimberg H, Mansouri A, Collombat P (2013) Dev Cell 26: 86-100 Mature chief cells are cryptic progenitors for metaplasia in the stomach. Nam KT, Lee HJ, Sousa JF, Weis VG, O'Neal RL, Finke PE, Romero-Gallo J, Shi G, Mills JC, Peek RM, Konieczny SF, Goldenring JR (2010) Gastroenterology 139: 2028-2037.e9 Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice. Scholten D, Osterreicher CH, Scholten A, Iwaisako K, Gu G, Brenner DA, Kisseleva T (2010) Gastroenterology 139: 987-98 Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions. Choi E, Hendley AM, Bailey JM, Leach SD, Goldenring JR (2016) Gastroenterology 150: 918-30.e13 Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas. Fukuda A, Kawaguchi Y, Furuyama K, Kodama S, Horiguchi M, Kuhara T, Koizumi M, Boyer DF, Fujimoto K, Doi R, Kageyama R, Wright CV, Chiba T (2006) J Clin Invest 116: 1484-93 Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration. Majka SM, Jackson KA, Kienstra KA, Majesky MW, Goodell MA, Hirschi KK (2003) J Clin Invest 111: 71-9 Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. Xuan S, Borok MJ, Decker KJ, Battle MA, Duncan SA, Hale MA, Macdonald RJ, Sussel L (2012) J Clin Invest 122: 3516-28 Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction. Gaskill CF, Carrier EJ, Kropski JA, Bloodworth NC, Menon S, Foronjy RF, Taketo MM, Hong CC, Austin ED, West JD, Means AL, Loyd JE, Merryman WD, Hemnes AR, De Langhe S, Blackwell TS, Klemm DJ, Majka SM (2017) J Clin Invest 127: 2262-2276 The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. Winnier GE, Hargett L, Hogan BL (1997) Genes Dev 11: 926-40 Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity. Lee CS, Perreault N, Brestelli JE, Kaestner KH (2002) Genes Dev 16: 1488-97 Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia. Sund NJ, Vatamaniuk MZ, Casey M, Ang SL, Magnuson MA, Stoffers DA, Matschinsky FM, Kaestner KH (2001) Genes Dev 15: 1706-15 Genetic interactions between hepatocyte nuclear factor-6 and Notch signaling regulate mouse intrahepatic bile duct development in vivo. Vanderpool C, Sparks EE, Huppert KA, Gannon M, Means AL, Huppert SS (2012) Hepatology 55: 233-43 Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation. Wu B, Wang Y, Lui W, Langworthy M, Tompkins KL, Hatzopoulos AK, Baldwin HS, Zhou B (2011) Circ Res 109: 183-92 Development of the coronary vessel system. Reese DE, Mikawa T, Bader DM (2002) Circ Res 91: 761-8 Epithelial organization, cell polarity and tumorigenesis. McCaffrey LM, Macara IG (2011) Trends Cell Biol 21: 727-35 Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide. Alam SM, Aussedat B, Vohra Y, Meyerhoff RR, Cale EM, Walkowicz WE, Radakovich NA, Anasti K, Armand L, Parks R, Sutherland L, Scearce R, Joyce MG, Pancera M, Druz A, Georgiev IS, Von Holle T, Eaton A, Fox C, Reed SG, Louder M, Bailer RT, Morris L, Abdool-Karim SS, Cohen M, Liao HX, Montefiori DC, Park PK, Fernández-Tejada A, Wiehe K, Santra S, Kepler TB, Saunders KO, Sodroski J, Kwong PD, Mascola JR, Bonsignori M, Moody MA, Danishefsky S, Haynes BF (2017) Sci Transl Med 9: Spasmolytic polypeptide-expressing metaplasia (SPEM) in the gastric oxyntic mucosa does not arise from Lgr5-expressing cells. Nam KT, O'Neal RL, Coffey RJ, Finke PE, Barker N, Goldenring JR (2012) Gut 61: 1678-85 Lrig1+ gastric isthmal progenitor cells restore normal gastric lineage cells during damage recovery in adult mouse stomach. Choi E, Lantz TL, Vlacich G, Keeley TM, Samuelson LC, Coffey RJ, Goldenring JR, Powell AE (2018) Gut 67: 1595-1605 Cell lineage distribution atlas of the human stomach reveals heterogeneous gland populations in the gastric antrum. Choi E, Roland JT, Barlow BJ, O'Neal R, Rich AE, Nam KT, Shi C, Goldenring JR (2014) Gut 63: 1711-20 A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells. Moad M, Pal D, Hepburn AC, Williamson SC, Wilson L, Lako M, Armstrong L, Hayward SW, Franco OE, Cates JM, Fordham SE, Przyborski S, Carr-Wilkinson J, Robson CN, Heer R (2013) Eur Urol 64: 753-61 Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis. Larsen HL, Martín-Coll L, Nielsen AV, Wright CVE, Trusina A, Kim YH, Grapin-Botton A (2017) Nat Commun 8: 605
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