Identification of a naturally occurring peroxidase-lipoxygenase fusion protein. Koljak R, Boutaud O, Shieh BH, Samel N, Brash AR (1997) Science 277: 1994-6 The origin of 15R-prostaglandins in the Caribbean coral Plexaura homomalla: molecular cloning and expression of a novel cyclooxygenase. Valmsen K, Järving I, Boeglin WE, Varvas K, Koljak R, Pehk T, Brash AR, Samel N (2001) Proc Natl Acad Sci U S A 98: 7700-5 Evidence of a cyclooxygenase-related prostaglandin synthesis in coral. The allene oxide pathway is not involved in prostaglandin biosynthesis. Varvas K, Järving I, Koljak R, Valmsen K, Brash AR, Samel N (1999) J Biol Chem 274: 9923-9 On the evolutionary origin of cyclooxygenase (COX) isozymes: characterization of marine invertebrate COX genes points to independent duplication events in vertebrate and invertebrate lineages. Järving R, Järving I, Kurg R, Brash AR, Samel N (2004) J Biol Chem 279: 13624-33 The basis of prostaglandin synthesis in coral: molecular cloning and expression of a cyclooxygenase from the Arctic soft coral Gersemia fruticosa. Koljak R, Järving I, Kurg R, Boeglin WE, Varvas K, Valmsen K, Ustav M, Brash AR, Samel N (2001) J Biol Chem 276: 7033-40 Purification and catalytic activities of the two domains of the allene oxide synthase-lipoxygenase fusion protein of the coral Plexaura homomalla. Boutaud O, Brash AR (1999) J Biol Chem 274: 33764-70 Purification and molecular cloning of an 8R-lipoxygenase from the coral Plexaura homomalla reveal the related primary structures of R- and S-lipoxygenases. Brash AR, Boeglin WE, Chang MS, Shieh BH (1996) J Biol Chem 271: 20949-57 Characterization of the coral allene oxide synthase active site with UV-visible absorption, magnetic circular dichroism, and electron paramagnetic resonance spectroscopy: evidence for tyrosinate ligation to the ferric enzyme heme iron. Abraham BD, Sono M, Boutaud O, Shriner A, Dawson JH, Brash AR, Gaffney BJ (2001) Biochemistry 40: 2251-9 Investigation of the allene oxide pathway in the coral Plexaura homomalla: formation of novel ketols and isomers of prostaglandin A2 from 15-hydroxyeicosatetraenoic acid. Song WC, Brash AR (1991) Arch Biochem Biophys 290: 427-35 Detection of the 15-acetate of prostaglandin E2 methyl ester as a prominent component of the prostaglandins in the gorgonian coral Plexaura homomalla. Schneider C, Manier ML, Hachey DL, Brash AR (2002) Lipids 37: 217-21
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.