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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Oxygenases are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Oxygenases.
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Publications
- Genetic determinants of response to warfarin during initial anticoagulation.
Schwarz UI, Ritchie MD, Bradford Y, Li C, Dudek SM, Frye-Anderson A, Kim RB, Roden DM, Stein CM
(2008) N Engl J Med 358: 999-1008 - Estimation of the warfarin dose with clinical and pharmacogenetic data.
International Warfarin Pharmacogenetics Consortium, Klein TE, Altman RB, Eriksson N, Gage BF, Kimmel SE, Lee MT, Limdi NA, Page D, Roden DM, Wagner MJ, Caldwell MD, Johnson JA
(2009) N Engl J Med 360: 753-64 - Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.
Perera MA, Cavallari LH, Limdi NA, Gamazon ER, Konkashbaev A, Daneshjou R, Pluzhnikov A, Crawford DC, Wang J, Liu N, Tatonetti N, Bourgeois S, Takahashi H, Bradford Y, Burkley BM, Desnick RJ, Halperin JL, Khalifa SI, Langaee TY, Lubitz SA, Nutescu EA, Oetjens M, Shahin MH, Patel SR, Sagreiya H, Tector M, Weck KE, Rieder MJ, Scott SA, Wu AH, Burmester JK, Wadelius M, Deloukas P, Wagner MJ, Mushiroda T, Kubo M, Roden DM, Cox NJ, Altman RB, Klein TE, Nakamura Y, Johnson JA
(2013) Lancet 382: 790-6 - Obesity-associated variants within FTO form long-range functional connections with IRX3.
Smemo S, Tena JJ, Kim KH, Gamazon ER, Sakabe NJ, Gómez-Marín C, Aneas I, Credidio FL, Sobreira DR, Wasserman NF, Lee JH, Puviindran V, Tam D, Shen M, Son JE, Vakili NA, Sung HK, Naranjo S, Acemel RD, Manzanares M, Nagy A, Cox NJ, Hui CC, Gomez-Skarmeta JL, Nóbrega MA
(2014) Nature 507: 371-5 - Cytochrome P-450 3A4: regulation and role in drug metabolism.
Guengerich FP
(1999) Annu Rev Pharmacol Toxicol 39: 1-17 - Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system.
Friemann R, Lee K, Brown EN, Gibson DT, Eklund H, Ramaswamy S
(2009) Acta Crystallogr D Biol Crystallogr 65: 24-33 - Arachidonic acid as a bioactive molecule.
Brash AR
(2001) J Clin Invest 107: 1339-45 - Angiotensin-independent mechanism for aldosterone synthesis during chronic extracellular fluid volume depletion.
Okubo S, Niimura F, Nishimura H, Takemoto F, Fogo A, Matsusaka T, Ichikawa I
(1997) J Clin Invest 99: 855-60 - Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs.
Barlow C, Dennery PA, Shigenaga MK, Smith MA, Morrow JD, Roberts LJ, Wynshaw-Boris A, Levine RL
(1999) Proc Natl Acad Sci U S A 96: 9915-9 - Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension.
Holla VR, Adas F, Imig JD, Zhao X, Price E, Olsen N, Kovacs WJ, Magnuson MA, Keeney DS, Breyer MD, Falck JR, Waterman MR, Capdevila JH
(2001) Proc Natl Acad Sci U S A 98: 5211-6 - Heparin-binding EGF-like growth factor mediates the biological effects of P450 arachidonate epoxygenase metabolites in epithelial cells.
Chen JK, Capdevila J, Harris RC
(2002) Proc Natl Acad Sci U S A 99: 6029-34 - Activation of heme biosynthesis by a small molecule that is toxic to fermenting Staphylococcus aureus.
Mike LA, Dutter BF, Stauff DL, Moore JL, Vitko NP, Aranmolate O, Kehl-Fie TE, Sullivan S, Reid PR, DuBois JL, Richardson AR, Caprioli RM, Sulikowski GA, Skaar EP
(2013) Proc Natl Acad Sci U S A 110: 8206-11 - A common X-linked inborn error of carnitine biosynthesis may be a risk factor for nondysmorphic autism.
Celestino-Soper PB, Violante S, Crawford EL, Luo R, Lionel AC, Delaby E, Cai G, Sadikovic B, Lee K, Lo C, Gao K, Person RE, Moss TJ, German JR, Huang N, Shinawi M, Treadwell-Deering D, Szatmari P, Roberts W, Fernandez B, Schroer RJ, Stevenson RE, Buxbaum JD, Betancur C, Scherer SW, Sanders SJ, Geschwind DH, Sutcliffe JS, Hurles ME, Wanders RJ, Shaw CA, Leal SM, Cook EH, Goin-Kochel RP, Vaz FM, Beaudet AL
(2012) Proc Natl Acad Sci U S A 109: 7974-81 - Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver.
Shimada T, Guengerich FP
(1989) Proc Natl Acad Sci U S A 86: 462-5 - Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
McCulloch KM, McCranie EK, Smith JA, Sarwar M, Mathieu JL, Gitschlag BL, Du Y, Bachmann BO, Iverson TM
(2015) Proc Natl Acad Sci U S A 112: 11547-52 - Regulation of the induction of a cytochrome P-450 prostaglandin omega-hydroxylase by pregnancy in rabbit lung.
Muerhoff AS, Williams DE, Leithauser MT, Jackson VE, Waterman MR, Masters BS
(1987) Proc Natl Acad Sci U S A 84: 7911-4 - Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapy.
Li C, Schwarz UI, Ritchie MD, Roden DM, Stein CM, Kurnik D
(2009) Blood 113: 3925-30 - Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy.
Gong IY, Tirona RG, Schwarz UI, Crown N, Dresser GK, Larue S, Langlois N, Lazo-Langner A, Zou G, Roden DM, Stein CM, Rodger M, Carrier M, Forgie M, Wells PS, Kim RB
(2011) Blood 118: 3163-71 - Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease.
Bean CJ, Boulet SL, Ellingsen D, Pyle ME, Barron-Casella EA, Casella JF, Payne AB, Driggers J, Trau HA, Yang G, Jones K, Ofori-Acquah SF, Hooper WC, DeBaun MR
(2012) Blood 120: 3822-8 - A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.
Cooper GM, Johnson JA, Langaee TY, Feng H, Stanaway IB, Schwarz UI, Ritchie MD, Stein CM, Roden DM, Smith JD, Veenstra DL, Rettie AE, Rieder MJ
(2008) Blood 112: 1022-7 - Induction of renal arachidonate cytochrome P-450 epoxygenase after uninephrectomy: counterregulation of hyperfiltration.
Takahashi K, Harris RC, Capdevila JH, Karara A, Makita K, Jacobson HR, Munger KA, Badr KF
(1993) J Am Soc Nephrol 3: 1496-500 - HO-1 in control of a self-eating kidney.
Kapitsinou PP, Haase VH
(2010) J Am Soc Nephrol 21: 1600-2 - Genetic predisposition to bladder cancer: ability to hydroxylate debrisoquine and mephenytoin as risk factors.
Kaisary A, Smith P, Jaczq E, McAllister CB, Wilkinson GR, Ray WA, Branch RA
(1987) Cancer Res 47: 5488-93 - Inactivation of 1,3-, 1,6-, and 1,8-dinitropyrene by cytochrome P-450 enzymes in human and rat liver microsomes.
Shimada T, Guengerich FP
(1990) Cancer Res 50: 2036-43 - Purification and characterization of xenobiotic-metabolizing enzymes from lung tissue.
Guengerich FP
(1990) Pharmacol Ther 45: 299-307 - Use of array CGH to detect exonic copy number variants throughout the genome in autism families detects a novel deletion in TMLHE.
Celestino-Soper PB, Shaw CA, Sanders SJ, Li J, Murtha MT, Ercan-Sencicek AG, Davis L, Thomson S, Gambin T, Chinault AC, Ou Z, German JR, Milosavljevic A, Sutcliffe JS, Cook EH, Stankiewicz P, State MW, Beaudet AL
(2011) Hum Mol Genet 20: 4360-70 - Interactions of ingested food, beverage, and tobacco components involving human cytochrome P4501A2, 2A6, 2E1, and 3A4 enzymes.
Guengerich FP, Shimada T, Yun CH, Yamazaki H, Raney KD, Thier R, Coles B, Harris TM
(1994) Environ Health Perspect 102 Suppl 9: 49-53 - Role for copper in transient oxidation and nuclear translocation of MTF-1, but not of NF-kappa B, by the heme-hemopexin transport system.
Vanacore RM, Eskew JD, Morales PJ, Sung L, Smith A
(2000) Antioxid Redox Signal 2: 739-52 - Hypothalamic peptidyl-glycine alpha-amidating monooxygenase: preliminary characterization.
Emeson RB
(1984) J Neurosci 4: 2604-13 - Decreased intestinal CYP3A in celiac disease: reversal after successful gluten-free diet: a potential source of interindividual variability in first-pass drug metabolism.
Lang CC, Brown RM, Kinirons MT, Deathridge MA, Guengerich FP, Kelleher D, O'Briain DS, Ghishan FK, Wood AJ
(1996) Clin Pharmacol Ther 59: 41-6 - The missing association: sequencing-based discovery of novel SNPs in VKORC1 and CYP2C9 that affect warfarin dose in African Americans.
Perera MA, Gamazon E, Cavallari LH, Patel SR, Poindexter S, Kittles RA, Nicolae D, Cox NJ
(2011) Clin Pharmacol Ther 89: 408-15 - Genetic determinants of dose and clinical outcomes in patients receiving oral anticoagulants.
Schwarz UI, Stein CM
(2006) Clin Pharmacol Ther 80: 7-12 - Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine.
Stein CM, Kinirons MT, Pincus T, Wilkinson GR, Wood AJ
(1996) Clin Pharmacol Ther 59: 47-51 - Formation of the indigo precursor indican in genetically engineered tobacco plants and cell cultures.
Warzecha H, Frank A, Peer M, Gillam EM, Guengerich FP, Unger M
(2007) Plant Biotechnol J 5: 185-91 - Control of oxygenation in lipoxygenase and cyclooxygenase catalysis.
Schneider C, Pratt DA, Porter NA, Brash AR
(2007) Chem Biol 14: 473-88 - Glucose and lactate biosensors for scanning electrochemical microscopy imaging of single live cells.
Ciobanu M, Taylor DE, Wilburn JP, Cliffel DE
(2008) Anal Chem 80: 2717-27 - 16Alpha-hydroxylation of estrone by human cytochrome P4503A4/5.
Huang Z, Guengerich FP, Kaminsky LS
(1998) Carcinogenesis 19: 867-72 - Generation of new protein kinase inhibitors utilizing cytochrome p450 mutant enzymes for indigoid synthesis.
Guengerich FP, Sorrells JL, Schmitt S, Krauser JA, Aryal P, Meijer L
(2004) J Med Chem 47: 3236-41
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