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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Purines are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Purines.
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Publications
- Targeting nonclassical oncogenes for therapy in T-ALL.
Subramaniam PS, Whye DW, Efimenko E, Chen J, Tosello V, De Keersmaecker K, Kashishian A, Thompson MA, Castillo M, Cordon-Cardo C, Davé UP, Ferrando A, Lannutti BJ, Diacovo TG
(2012) Cancer Cell 21: 459-72 - cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism.
Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA
(2005) Circ Res 96: 100-9 - Kinetics and mechanism of the general-acid-catalyzed ring-closure of the malondialdehyde-DNA adduct, N2-(3-oxo-1-propenyl)deoxyguanosine (N2OPdG-), to 3-(2'-Deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin- 10(3H)-one (M1dG).
Riggins JN, Pratt DA, Voehler M, Daniels JS, Marnett LJ
(2004) J Am Chem Soc 126: 10571-81 - Chemical properties of oxopropenyl adducts of purine and pyrimidine nucleosides and their reactivity toward amino acid cross-link formation.
Szekely J, Rizzo CJ, Marnett LJ
(2008) J Am Chem Soc 130: 2195-201 - Kinetic and thermodynamic analysis of the hydrolytic ring-opening of the malondialdehyde-deoxyguanosine adduct, 3-(2'-deoxy-beta-D-erythro-pentofuranosyl)- pyrimido[1,2-alpha]purin-10(3H)-one.
Riggins JN, Daniels JS, Rouzer CA, Marnett LJ
(2004) J Am Chem Soc 126: 8237-43 - Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer.
Formisano L, Lu Y, Servetto A, Hanker AB, Jansen VM, Bauer JA, Sudhan DR, Guerrero-Zotano AL, Croessmann S, Guo Y, Ericsson PG, Lee KM, Nixon MJ, Schwarz LJ, Sanders ME, Dugger TC, Cruz MR, Behdad A, Cristofanilli M, Bardia A, O'Shaughnessy J, Nagy RJ, Lanman RB, Solovieff N, He W, Miller M, Su F, Shyr Y, Mayer IA, Balko JM, Arteaga CL
(2019) Nat Commun 10: 1373 - Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde.
Fink SP, Reddy GR, Marnett LJ
(1997) Proc Natl Acad Sci U S A 94: 8652-7 - Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogenous carcinogen malondialdehyde.
VanderVeen LA, Hashim MF, Shyr Y, Marnett LJ
(2003) Proc Natl Acad Sci U S A 100: 14247-52 - In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG.
Otteneder MB, Knutson CG, Daniels JS, Hashim M, Crews BC, Remmel RP, Wang H, Rizzo C, Marnett LJ
(2006) Proc Natl Acad Sci U S A 103: 6665-9 - Transporter-mediated protection against thiopurine-induced hematopoietic toxicity.
Krishnamurthy P, Schwab M, Takenaka K, Nachagari D, Morgan J, Leslie M, Du W, Boyd K, Cheok M, Nakauchi H, Marzolini C, Kim RB, Poonkuzhali B, Schuetz E, Evans W, Relling M, Schuetz JD
(2008) Cancer Res 68: 4983-9 - Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M1dG.
Cline SD, Lodeiro MF, Marnett LJ, Cameron CE, Arnold JJ
(2010) Nucleic Acids Res 38: 7546-57 - Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA.
Wauchope OR, Mitchener MM, Beavers WN, Galligan JJ, Camarillo JM, Sanders WD, Kingsley PJ, Shim HN, Blackwell T, Luong T, deCaestecker M, Fessel JP, Marnett LJ
(2018) Nucleic Acids Res 46: 3458-3467 - Chronic treatment with sildenafil improves energy balance and insulin action in high fat-fed conscious mice.
Ayala JE, Bracy DP, Julien BM, Rottman JN, Fueger PT, Wasserman DH
(2007) Diabetes 56: 1025-33 - Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice.
Kang L, Ayala JE, Lee-Young RS, Zhang Z, James FD, Neufer PD, Pozzi A, Zutter MM, Wasserman DH
(2011) Diabetes 60: 416-26 - Methylthioadenosine phosphorylase and activated insulin-like growth factor-1 receptor/insulin receptor: potential therapeutic targets in chordoma.
Sommer J, Itani DM, Homlar KC, Keedy VL, Halpern JL, Holt GE, Schwartz HS, Coffin CM, Kelley MJ, Cates JM
(2010) J Pathol 220: 608-17 - Regulation of C/EBPbeta1 by Ras in mammary epithelial cells and the role of C/EBPbeta1 in oncogene-induced senescence.
Atwood AA, Sealy L
(2010) Oncogene 29: 6004-15 - 'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.
Lin X, Morgan-Lappe S, Huang X, Li L, Zakula DM, Vernetti LA, Fesik SW, Shen Y
(2007) Oncogene 26: 3972-9 - Analysis of substrate specificity of Schizosaccharomyces pombe Mag1 alkylpurine DNA glycosylase.
Adhikary S, Eichman BF
(2011) EMBO Rep 12: 1286-92 - Excessive nitric oxide function and blood pressure regulation in patients with autonomic failure.
Gamboa A, Shibao C, Diedrich A, Paranjape SY, Farley G, Christman B, Raj SR, Robertson D, Biaggioni I
(2008) Hypertension 51: 1531-6 - The effect of sildenafil on nitric oxide-mediated vasodilation in healthy men.
Dishy V, Sofowora G, Harris PA, Kandcer M, Zhan F, Wood AJ, Stein CM
(2001) Clin Pharmacol Ther 70: 270-9 - Effect of A2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells.
Ryzhov S, Zaynagetdinov R, Goldstein AE, Novitskiy SV, Dikov MM, Blackburn MR, Biaggioni I, Feoktistov I
(2008) J Immunol 180: 7212-20 - Long-term follow-up after conversion from intravenous epoprostenol to oral therapy with bosentan or sildenafil in 13 patients with pulmonary arterial hypertension.
Johnson RF, Loyd JE, Mullican AL, Fink CA, Robbins IM
(2007) J Heart Lung Transplant 26: 363-9 - Circadian expression of genes involved in the purine biosynthetic pathway of the cyanobacterium Synechococcus sp. strain PCC 7942.
Liu Y, Tsinoremas NF, Golden SS, Kondo T, Johnson CH
(1996) Mol Microbiol 20: 1071-81 - Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation.
Zhang H, Beckman JW, Guengerich FP
(2009) J Biol Chem 284: 35144-53 - Metabolism and elimination of the endogenous DNA adduct, 3-(2-deoxy-beta-D-erythropentofuranosyl)-pyrimido[1,2-alpha]purine-10(3H)-one, in the rat.
Knutson CG, Wang H, Rizzo CJ, Marnett LJ
(2007) J Biol Chem 282: 36257-64 - Identification of determinants required for agonistic and inverse agonistic ligand properties at the ADP receptor P2Y12.
Schmidt P, Ritscher L, Dong EN, Hermsdorf T, Cöster M, Wittkopf D, Meiler J, Schöneberg T
(2013) Mol Pharmacol 83: 256-66 - Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation.
Zhu CB, Hewlett WA, Feoktistov I, Biaggioni I, Blakely RD
(2004) Mol Pharmacol 65: 1462-74 - Mitochondrial-encoded membrane protein transcripts are pyrimidine-rich while soluble protein transcripts and ribosomal RNA are purine-rich.
Bradshaw PC, Rathi A, Samuels DC
(2005) BMC Genomics 6: 136 - Purine Biosynthesis Metabolically Constrains Intracellular Survival of Uropathogenic Escherichia coli.
Shaffer CL, Zhang EW, Dudley AG, Dixon BREA, Guckes KR, Breland EJ, Floyd KA, Casella DP, Algood HMS, Clayton DB, Hadjifrangiskou M
(2017) Infect Immun 85: - Purine-rich foods, protein intake, and the prevalence of hyperuricemia: the Shanghai Men's Health Study.
Villegas R, Xiang YB, Elasy T, Xu WH, Cai H, Cai Q, Linton MF, Fazio S, Zheng W, Shu XO
(2012) Nutr Metab Cardiovasc Dis 22: 409-16 - Sildenafil monotherapy in portopulmonary hypertension can facilitate liver transplantation.
Hemnes AR, Robbins IM
(2009) Liver Transpl 15: 15-9 - Kinetic analysis of base-pairing preference for nucleotide incorporation opposite template pyrimidines by human DNA polymerase iota.
Choi JY, Lim S, Eoff RL, Guengerich FP
(2009) J Mol Biol 389: 264-74 - The relative contribution of adduct blockage and DNA repair on template utilization during replication of 1,N2-propanodeoxyguanosine and pyrimido.
Fink SP, Marnett LJ
(2001) Mutat Res 485: 209-18 - Tachycardia caused by A2A adenosine receptor agonists is mediated by direct sympathoexcitation in awake rats.
Dhalla AK, Wong MY, Wang WQ, Biaggioni I, Belardinelli L
(2006) J Pharmacol Exp Ther 316: 695-702 - Nuclear Oxidation of a Major Peroxidation DNA Adduct, M1dG, in the Genome.
Wauchope OR, Beavers WN, Galligan JJ, Mitchener MM, Kingsley PJ, Marnett LJ
(2015) Chem Res Toxicol 28: 2334-42 - Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M1dG {3-(2-deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin-10(3H)-one}, by accelerator mass spectrometry.
Knutson CG, Skipper PL, Liberman RG, Tannenbaum SR, Marnett LJ
(2008) Chem Res Toxicol 21: 1290-4 - Reaction of malondialdehyde-DNA adducts with hydrazines-development of a facile assay for quantification of malondialdehyde equivalents in DNA.
Otteneder M, Plastaras JP, Marnett LJ
(2002) Chem Res Toxicol 15: 312-8 - Pyrimido[1,2-alpha]purin-10(3H)-one: a reactive electrophile in the genome.
Schnetz-Boutaud N, Daniels JS, Hashim MF, Scholl P, Burrus T, Marnett LJ
(2000) Chem Res Toxicol 13: 967-70
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