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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Sodium Chloride are shown below. Double-click or tap a node for more information.
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- Long-term use of thiazide diuretics and risk of hip fracture.
Ray WA, Griffin MR, Downey W, Melton LJ
(1989) Lancet 1: 687-90 - Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities.
Boyden LM, Choi M, Choate KA, Nelson-Williams CJ, Farhi A, Toka HR, Tikhonova IR, Bjornson R, Mane SM, Colussi G, Lebel M, Gordon RD, Semmekrot BA, Poujol A, Välimäki MJ, De Ferrari ME, Sanjad SA, Gutkin M, Karet FE, Tucci JR, Stockigt JR, Keppler-Noreuil KM, Porter CC, Anand SK, Whiteford ML, Davis ID, Dewar SB, Bettinelli A, Fadrowski JJ, Belsha CW, Hunley TE, Nelson RD, Trachtman H, Cole TR, Pinsk M, Bockenhauer D, Shenoy M, Vaidyanathan P, Foreman JW, Rasoulpour M, Thameem F, Al-Shahrouri HZ, Radhakrishnan J, Gharavi AG, Goilav B, Lifton RP
(2012) Nature 482: 98-102 - The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum.
Howard HC, Mount DB, Rochefort D, Byun N, Dupré N, Lu J, Fan X, Song L, Rivière JB, Prévost C, Horst J, Simonati A, Lemcke B, Welch R, England R, Zhan FQ, Mercado A, Siesser WB, George AL, McDonald MP, Bouchard JP, Mathieu J, Delpire E, Rouleau GA
(2002) Nat Genet 32: 384-92 - Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter.
Delpire E, Lu J, England R, Dull C, Thorne T
(1999) Nat Genet 22: 192-5 - Cryo-EM structures of the human cation-chloride cotransporter KCC1.
Liu S, Chang S, Han B, Xu L, Zhang M, Zhao C, Yang W, Wang F, Li J, Delpire E, Ye S, Bai XC, Guo J
(2019) Science 366: 505-508 - Shape analysis of the histone octamer in solution.
Uberbacher EC, Harp JM, Wilkinson-Singley E, Bunick GJ
(1986) Science 232: 1247-9 - Assessing Toxicity of Intravenous Crystalloids in Critically Ill Patients.
Kellum JA, Shaw AD
(2015) JAMA 314: 1695-7 - NKCC1 transporter facilitates seizures in the developing brain.
Dzhala VI, Talos DM, Sdrulla DA, Brumback AC, Mathews GC, Benke TA, Delpire E, Jensen FE, Staley KJ
(2005) Nat Med 11: 1205-13 - Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway.
Perry JSA, Morioka S, Medina CB, Iker Etchegaray J, Barron B, Raymond MH, Lucas CD, Onengut-Gumuscu S, Delpire E, Ravichandran KS
(2019) Nat Cell Biol 21: 1532-1543 - Trends in antihypertensive drug advertising, 1985-1996.
Wang TJ, Ausiello JC, Stafford RS
(1999) Circulation 99: 2055-7 - AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure.
Gurley SB, Riquier-Brison ADM, Schnermann J, Sparks MA, Allen AM, Haase VH, Snouwaert JN, Le TH, McDonough AA, Koller BH, Coffman TM
(2011) Cell Metab 13: 469-475 - Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention.
Ahn D, Ge Y, Stricklett PK, Gill P, Taylor D, Hughes AK, Yanagisawa M, Miller L, Nelson RD, Kohan DE
(2004) J Clin Invest 114: 504-11 - High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.
Kitada K, Daub S, Zhang Y, Klein JD, Nakano D, Pedchenko T, Lantier L, LaRocque LM, Marton A, Neubert P, Schröder A, Rakova N, Jantsch J, Dikalova AE, Dikalov SI, Harrison DG, Müller DN, Nishiyama A, Rauh M, Harris RC, Luft FC, Wassermann DH, Sands JM, Titze J
(2017) J Clin Invest 127: 1944-1959 - Atrial natriuretic peptide is negatively regulated by microRNA-425.
Arora P, Wu C, Khan AM, Bloch DB, Davis-Dusenbery BN, Ghorbani A, Spagnolli E, Martinez A, Ryan A, Tainsh LT, Kim S, Rong J, Huan T, Freedman JE, Levy D, Miller KK, Hata A, Del Monte F, Vandenwijngaert S, Swinnen M, Janssens S, Holmes TM, Buys ES, Bloch KD, Newton-Cheh C, Wang TJ
(2013) J Clin Invest 123: 3378-82 - Integrated compensatory network is activated in the absence of NCC phosphorylation.
Grimm PR, Lazo-Fernandez Y, Delpire E, Wall SM, Dorsey SG, Weinman EJ, Coleman R, Wade JB, Welling PA
(2015) J Clin Invest 125: 2136-50 - Immune cells control skin lymphatic electrolyte homeostasis and blood pressure.
Wiig H, Schröder A, Neuhofer W, Jantsch J, Kopp C, Karlsen TV, Boschmann M, Goss J, Bry M, Rakova N, Dahlmann A, Brenner S, Tenstad O, Nurmi H, Mervaala E, Wagner H, Beck FX, Müller DN, Kerjaschki D, Luft FC, Harrison DG, Alitalo K, Titze J
(2013) J Clin Invest 123: 2803-15 - Role of insulin in the regulation of leucine kinetics in the conscious dog.
Abumrad NN, Jefferson LS, Rannels SR, Williams PE, Cherrington AD, Lacy WW
(1982) J Clin Invest 70: 1031-41 - Role of p38 in the regulation of renal cortical cyclooxygenase-2 expression by extracellular chloride.
Cheng HF, Wang JL, Zhang MZ, McKanna JA, Harris RC
(2000) J Clin Invest 106: 681-8 - Collagen-mediated platelet aggregation. Evidence for multivalent interactions of intermediate specificity between collagen and platelets.
Santoro SA, Cunningham LW
(1977) J Clin Invest 60: 1054-60 - Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice.
Zhang MZ, Yao B, Wang S, Fan X, Wu G, Yang H, Yin H, Yang S, Harris RC
(2011) J Clin Invest 121: 2845-54 - CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli.
Itani HA, Xiao L, Saleh MA, Wu J, Pilkinton MA, Dale BL, Barbaro NR, Foss JD, Kirabo A, Montaniel KR, Norlander AE, Chen W, Sato R, Navar LG, Mallal SA, Madhur MS, Bernstein KE, Harrison DG
(2016) Circ Res 118: 1233-43 - Aversive gustatory stimulation activates limbic circuits in humans.
Zald DH, Lee JT, Fluegel KW, Pardo JV
(1998) Brain 121 ( Pt 6): 1143-54 - Renal cortical cyclooxygenase 2 expression is differentially regulated by angiotensin II AT(1) and AT(2) receptors.
Zhang MZ, Yao B, Cheng HF, Wang SW, Inagami T, Harris RC
(2006) Proc Natl Acad Sci U S A 103: 16045-50 - Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules.
Grimm PR, Coleman R, Delpire E, Welling PA
(2017) J Am Soc Nephrol 28: 2597-2606 - Regulation of Helicobacter pylori cagA expression in response to salt.
Loh JT, Torres VJ, Cover TL
(2007) Cancer Res 67: 4709-15 - Characterization of DNA with an 8-oxoguanine modification.
Singh SK, Szulik MW, Ganguly M, Khutsishvili I, Stone MP, Marky LA, Gold B
(2011) Nucleic Acids Res 39: 6789-801 - Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.
Luther JM, Luo P, Wang Z, Cohen SE, Kim HS, Fogo AB, Brown NJ
(2012) Kidney Int 82: 643-51 - Effect of salt supplementation on amphotericin B nephrotoxicity.
Llanos A, Cieza J, Bernardo J, Echevarria J, Biaggioni I, Sabra R, Branch RA
(1991) Kidney Int 40: 302-8 - Aldosterone antagonism or synthase inhibition reduces end-organ damage induced by treatment with angiotensin and high salt.
Lea WB, Kwak ES, Luther JM, Fowler SM, Wang Z, Ma J, Fogo AB, Brown NJ
(2009) Kidney Int 75: 936-44 - Reduced activity of antioxidant enzymes underlies contrast media-induced renal injury in volume depletion.
Yoshioka T, Fogo A, Beckman JK
(1992) Kidney Int 41: 1008-15 - The roles of insulin, glucagon, and free fatty acids in the regulation of ketogenesis in dogs.
Keller U, Chiasson JL, Liljenquist JE, Cherrington AD, Jennings AS, Crofford OS
(1977) Diabetes 26: 1040-51 - Hexokinase II overexpression improves exercise-stimulated but not insulin-stimulated muscle glucose uptake in high-fat-fed C57BL/6J mice.
Fueger PT, Bracy DP, Malabanan CM, Pencek RR, Granner DK, Wasserman DH
(2004) Diabetes 53: 306-14 - NKCC1 phosphorylation stimulates neurite growth of injured adult sensory neurons.
Pieraut S, Laurent-Matha V, Sar C, Hubert T, Méchaly I, Hilaire C, Mersel M, Delpire E, Valmier J, Scamps F
(2007) J Neurosci 27: 6751-9 - Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice.
Sung KW, Kirby M, McDonald MP, Lovinger DM, Delpire E
(2000) J Neurosci 20: 7531-8 - Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter.
Barker EL, Moore KR, Rakhshan F, Blakely RD
(1999) J Neurosci 19: 4705-17 - Losartan blocks aldosterone and renal vascular responses to angiotensin II in humans.
Gandhi SK, Ryder DH, Brown NJ
(1996) Hypertension 28: 961-6 - Caffeine attenuates the renal vascular response to angiotensin II infusion.
Brown NJ, Ryder D, Nadeau J
(1993) Hypertension 22: 847-52
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