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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Calpain are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Calpain.
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- Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.
Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI
(2000) Nat Genet 26: 163-75 - A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance.
Baier LJ, Permana PA, Yang X, Pratley RE, Hanson RL, Shen GQ, Mott D, Knowler WC, Cox NJ, Horikawa Y, Oda N, Bell GI, Bogardus C
(2000) J Clin Invest 106: R69-73 - Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.
Tian X, Kim JJ, Monkley SM, Gotoh N, Nandez R, Soda K, Inoue K, Balkin DM, Hassan H, Son SH, Lee Y, Moeckel G, Calderwood DA, Holzman LB, Critchley DR, Zent R, Reiser J, Ishibe S
(2014) J Clin Invest 124: 1098-113 - Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus.
Fullerton SM, Bartoszewicz A, Ybazeta G, Horikawa Y, Bell GI, Kidd KK, Cox NJ, Hudson RR, Di Rienzo A
(2002) Am J Hum Genet 70: 1096-106 - Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.
Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, Walker M, Levy JC, O'Rahilly S, Rao PV, Bennett AJ, Jones EC, Menzel S, Prestwich P, Simecek N, Wishart M, Dhillon R, Fletcher C, Millward A, Demaine A, Wilkin T, Horikawa Y, Cox NJ, Bell GI, Ellard S, McCarthy MI, Hattersley AT
(2001) Am J Hum Genet 69: 544-52 - Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort.
Fingerlin TE, Erdos MR, Watanabe RM, Wiles KR, Stringham HM, Mohlke KL, Silander K, Valle TT, Buchanan TA, Tuomilehto J, Bergman RN, Boehnke M, Collins FS
(2002) Diabetes 51: 1644-8 - Patterns of linkage disequilibrium in the type 2 diabetes gene calpain-10.
Hayes MG, del Bosque-Plata L, Tsuchiya T, Hanis CL, Bell GI, Cox NJ
(2005) Diabetes 54: 3573-6 - Calpains play a role in insulin secretion and action.
Sreenan SK, Zhou YP, Otani K, Hansen PA, Currie KP, Pan CY, Lee JP, Ostrega DM, Pugh W, Horikawa Y, Cox NJ, Hanis CL, Burant CF, Fox AP, Bell GI, Polonsky KS
(2001) Diabetes 50: 2013-20 - Variation in the calpain-10 gene affects blood glucose levels in the British population.
Lynn S, Evans JC, White C, Frayling TM, Hattersley AT, Turnbull DM, Horikawa Y, Cox NJ, Bell GI, Walker M
(2002) Diabetes 51: 247-50 - Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians.
Rasmussen SK, Urhammer SA, Berglund L, Jensen JN, Hansen L, Echwald SM, Borch-Johnsen K, Horikawa Y, Mashima H, Lithell H, Cox NJ, Hansen T, Bell GI, Pedersen O
(2002) Diabetes 51: 3561-7 - Linkage of calpain 10 to type 2 diabetes: the biological rationale.
Cox NJ, Hayes MG, Roe CA, Tsuchiya T, Bell GI
(2004) Diabetes 53 Suppl 1: S19-25 - Challenges in identifying genetic variation affecting susceptibility to type 2 diabetes: examples from studies of the calpain-10 gene.
Cox NJ
(2001) Hum Mol Genet 10: 2301-5 - Calpain-10 interacts with plasma saturated fatty acid concentrations to influence insulin resistance in individuals with the metabolic syndrome.
Perez-Martinez P, Delgado-Lista J, Garcia-Rios A, Ferguson JF, Gulseth HL, Williams CM, Karlström B, Kieć-Wilk B, Blaak EE, Helal O, Małczewska-Malec M, Defoort C, Risérus U, Saris WH, Lovegrove JA, Drevon CA, Roche HM, Lopez-Miranda J
(2011) Am J Clin Nutr 93: 1136-41 - Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes.
Pihlajamäki J, Salmenniemi U, Vänttinen M, Ruotsalainen E, Kuusisto J, Vauhkonen I, Kainulainen S, Ng MC, Cox NJ, Bell GI, Laakso M
(2006) Diabetologia 49: 1560-6 - Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome.
Haddad L, Evans JC, Gharani N, Robertson C, Rush K, Wiltshire S, Frayling TM, Wilkin TJ, Demaine A, Millward A, Hattersley AT, Conway G, Cox NJ, Bell GI, Franks S, McCarthy MI
(2002) J Clin Endocrinol Metab 87: 2606-10 - Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians.
Elbein SC, Chu W, Ren Q, Hemphill C, Schay J, Cox NJ, Hanis CL, Hasstedt SJ
(2002) J Clin Endocrinol Metab 87: 650-4 - Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome.
Ehrmann DA, Schwarz PE, Hara M, Tang X, Horikawa Y, Imperial J, Bell GI, Cox NJ
(2002) J Clin Endocrinol Metab 87: 1669-73 - Regulation of focal complex composition and disassembly by the calcium-dependent protease calpain.
Bhatt A, Kaverina I, Otey C, Huttenlocher A
(2002) J Cell Sci 115: 3415-25 - Reovirus-induced apoptosis is preceded by increased cellular calpain activity and is blocked by calpain inhibitors.
Debiasi RL, Squier MK, Pike B, Wynes M, Dermody TS, Cohen JJ, Tyler KL
(1999) J Virol 73: 695-701 - Regulated intramembrane cleavage of the EGF receptor.
Liao HJ, Carpenter G
(2012) Traffic 13: 1106-12 - Mechanism of down-regulation of RNA polymerase III-transcribed non-coding RNA genes in macrophages by Leishmania.
Rana T, Misra S, Mittal MK, Farrow AL, Wilson KT, Linton MF, Fazio S, Willis IM, Chaudhuri G
(2011) J Biol Chem 286: 6614-26 - Helicobacter pylori VacA disrupts apical membrane-cytoskeletal interactions in gastric parietal cells.
Wang F, Xia P, Wu F, Wang D, Wang W, Ward T, Liu Y, Aikhionbare F, Guo Z, Powell M, Liu B, Bi F, Shaw A, Zhu Z, Elmoselhi A, Fan D, Cover TL, Ding X, Yao X
(2008) J Biol Chem 283: 26714-25 - Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes.
Lim CC, Zuppinger C, Guo X, Kuster GM, Helmes M, Eppenberger HM, Suter TM, Liao R, Sawyer DB
(2004) J Biol Chem 279: 8290-9 - Haplotype structure and phylogenetic shadowing of a hypervariable region in the CAPN10 gene.
Clark VJ, Cox NJ, Hammond M, Hanis CL, Di Rienzo A
(2005) Hum Genet 117: 258-66 - Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study.
Meyer TE, Boerwinkle E, Morrison AC, Volcik KA, Sanderson M, Coker AL, Pankow JS, Folsom AR
(2010) Cancer Epidemiol Biomarkers Prev 19: 558-65 - The interaction with the cytoplasmic loops of rhodopsin plays a crucial role in arrestin activation and binding.
Raman D, Osawa S, Gurevich VV, Weiss ER
(2003) J Neurochem 84: 1040-50 - Nicotinic acetylcholine receptor α1 promotes calpain-1 activation and macrophage inflammation in hypercholesterolemic nephropathy.
Zhang G, Thomas AL, Marshall AL, Kernan KA, Su Y, Zheng Y, Takano J, Saido TC, Eddy AA
(2011) Lab Invest 91: 106-23 - The kinder side of killer proteases: caspase activation contributes to neuroprotection and CNS remodeling.
McLaughlin B
(2004) Apoptosis 9: 111-21 - Calpain 10 and genetics of type 2 diabetes.
Cox NJ
(2002) Curr Diab Rep 2: 186-90 - A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.
Zhou YP, Sreenan S, Pan CY, Currie KP, Bindokas VP, Horikawa Y, Lee JP, Ostrega D, Ahmed N, Baldwin AC, Cox NJ, Fox AP, Miller RJ, Bell GI, Polonsky KS
(2003) Metabolism 52: 528-34 - Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses.
Tsuchiya T, Schwarz PE, Bosque-Plata LD, Geoffrey Hayes M, Dina C, Froguel P, Wayne Towers G, Fischer S, Temelkova-Kurktschiev T, Rietzsch H, Graessler J, Vcelák J, Palyzová D, Selisko T, Bendlová B, Schulze J, Julius U, Hanefeld M, Weedon MN, Evans JC, Frayling TM, Hattersley AT, Orho-Melander M, Groop L, Malecki MT, Hansen T, Pedersen O, Fingerlin TE, Boehnke M, Hanis CL, Cox NJ, Bell GI
(2006) Mol Genet Metab 89: 174-84 - Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population.
del Bosque-Plata L, Aguilar-Salinas CA, Tusié-Luna MT, Ramírez-Jiménez S, Rodríguez-Torres M, Aurón-Gómez M, Ramírez E, Velasco-Pérez ML, Ramírez-Silva A, Gómez-Pérez F, Hanis CL, Tsuchiya T, Yoshiuchi I, Cox NJ, Bell GI
(2004) Mol Genet Metab 81: 122-6 - Preventing the autophagic survival response by inhibition of calpain enhances the cytotoxic activity of bortezomib in vitro and in vivo.
Escalante AM, McGrath RT, Karolak MR, Dorr RT, Lynch RM, Landowski TH
(2013) Cancer Chemother Pharmacol 71: 1567-76 - Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population.
Iwasaki N, Horikawa Y, Tsuchiya T, Kitamura Y, Nakamura T, Tanizawa Y, Oka Y, Hara K, Kadowaki T, Awata T, Honda M, Yamashita K, Oda N, Yu L, Yamada N, Ogata M, Kamatani N, Iwamoto Y, Del Bosque-Plata L, Hayes MG, Cox NJ, Bell GI
(2005) J Hum Genet 50: 92-8
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