-
Communities
-
Explore Vanderbilt communities
By latest
Featured community
Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
-
- Resources
-
People
-
Publications
-
Explore publications
-
Keyword Connections
Connections to 8,11,14-Eicosatrienoic Acid are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for 8,11,14-Eicosatrienoic Acid.
Members
- No matching connections
Resources
- No matching connections
Communities
- No matching connections
Publications
- EET signaling in cancer.
Panigrahy D, Greene ER, Pozzi A, Wang DW, Zeldin DC
(2011) Cancer Metastasis Rev 30: 525-40 - Acute tissue-type plasminogen activator release in human microvascular endothelial cells: the roles of Galphaq, PLC-beta, IP3 and 5,6-epoxyeicosatrienoic acid.
Muldowney JA, Painter CA, Sanders-Bush E, Brown NJ, Vaughan DE
(2007) Thromb Haemost 97: 263-71 - Mitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metabolite.
Chen J, Chen JK, Falck JR, Guthi JS, Anjaiah S, Capdevila JH, Harris RC
(2007) Mol Cell Biol 27: 3023-34 - Epoxyeicosatrienoic acids and their sulfonimide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells.
Chen JK, Falck JR, Reddy KM, Capdevila J, Harris RC
(1998) J Biol Chem 273: 29254-61 - Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor.
Chen JK, Wang DW, Falck JR, Capdevila J, Harris RC
(1999) J Biol Chem 274: 4764-9 - Overexpression of C-terminal Src kinase blocks 14, 15-epoxyeicosatrienoic acid-induced tyrosine phosphorylation and mitogenesis.
Chen JK, Capdevila J, Harris RC
(2000) J Biol Chem 275: 13789-92 - Cytochrome P-450 arachidonic acid epoxygenase. Regulatory control of the renal epoxygenase by dietary salt loading.
Capdevila JH, Wei S, Yan J, Karara A, Jacobson HR, Falck JR, Guengerich FP, DuBois RN
(1992) J Biol Chem 267: 21720-6 - Epoxyeicosatrienoic acids (EETs) regulate epithelial sodium channel activity by extracellular signal-regulated kinase 1/2 (ERK1/2)-mediated phosphorylation.
Pidkovka N, Rao R, Mei S, Gong Y, Harris RC, Wang WH, Capdevila JH
(2013) J Biol Chem 288: 5223-31 - The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3.
Capdevila JH, Wei S, Helvig C, Falck JR, Belosludtsev Y, Truan G, Graham-Lorence SE, Peterson JA
(1996) J Biol Chem 271: 22663-71 - A keratinocyte-specific epoxygenase, CYP2B12, metabolizes arachidonic acid with unusual selectivity, producing a single major epoxyeicosatrienoic acid.
Keeney DS, Skinner C, Wei S, Friedberg T, Waterman MR
(1998) J Biol Chem 273: 9279-84 - Arachidonic acid metabolism in rabbit renal cortex. Formation of two novel dihydroxyeicosatrienoic acids.
Oliw EH, Lawson JA, Brash AR, Oates JA
(1981) J Biol Chem 256: 9924-31 - Characterization of 5,6- and 8,9-epoxyeicosatrienoic acids (5,6- and 8,9-EET) as potent in vivo angiogenic lipids.
Pozzi A, Macias-Perez I, Abair T, Wei S, Su Y, Zent R, Falck JR, Capdevila JH
(2005) J Biol Chem 280: 27138-46 - Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction.
Teder T, Boeglin WE, Brash AR
(2014) J Lipid Res 55: 2587-96 - 8R-Lipoxygenase-catalyzed synthesis of a prominent cis-epoxyalcohol from dihomo-γ-linolenic acid: a distinctive transformation compared with S-lipoxygenases.
Jin J, Boeglin WE, Cha JK, Brash AR
(2012) J Lipid Res 53: 292-9 - Epoxyeicosatrienoic acids activate Na+/H+ exchange and are mitogenic in cultured rat glomerular mesangial cells.
Harris RC, Homma T, Jacobson HR, Capdevila J
(1990) J Cell Physiol 144: 429-37 - A biosynthetic pathway generating 12-hydroxy-5,8,14-eicosatrienoic acid from arachidonic acid is active in mouse skin microsomes.
Du L, Yermalitsky V, Hachey DL, Jagadeesh SG, Falck JR, Keeney DS
(2006) J Pharmacol Exp Ther 316: 371-9 - Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid.
Imig JD, Zhao X, Falck JR, Wei S, Capdevila JH
(2001) J Hypertens 19: 983-92 - Streptomyces coelicolor A3(2) CYP102 protein, a novel fatty acid hydroxylase encoded as a heme domain without an N-terminal redox partner.
Lamb DC, Lei L, Zhao B, Yuan H, Jackson CJ, Warrilow AG, Skaug T, Dyson PJ, Dawson ES, Kelly SL, Hachey DL, Waterman MR
(2010) Appl Environ Microbiol 76: 1975-80 - Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis.
Zeldin DC, Wei S, Falck JR, Hammock BD, Snapper JR, Capdevila JH
(1995) Arch Biochem Biophys 316: 443-51 - Epoxygenated Fatty Acids Inhibit Retinal Vascular Inflammation.
Capozzi ME, Hammer SS, McCollum GW, Penn JS
(2016) Sci Rep 6: 39211 - Determination of cytochrome P450 metabolites of arachidonic acid in coronary venous plasma during ischemia and reperfusion in dogs.
Nithipatikom K, DiCamelli RF, Kohler S, Gumina RJ, Falck JR, Campbell WB, Gross GJ
(2001) Anal Biochem 292: 115-24 - Chiral resolution of the epoxyeicosatrienoic acids, arachidonic acid epoxygenase metabolites.
Wei S, Brittin JJ, Falck JR, Anjaiah S, Nithipatikom K, Cui L, Campbell WB, Capdevila JH
(2006) Anal Biochem 352: 129-34 - Resolution of dihydroxyeicosanoates and of dihydroxyeicosatrienoates by chiral phase chromatography.
Capdevila JH, Wei S, Kumar A, Kobayashi J, Snapper JR, Zeldin DC, Bhatt RK, Falck JR
(1992) Anal Biochem 207: 236-40 - Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha.
Yu Z, Schneider C, Boeglin WE, Brash AR
(2007) Lipids 42: 491-7 - Epoxygenase metabolites contribute to nitric oxide-independent afferent arteriolar vasodilation in response to bradykinin.
Imig JD, Falck JR, Wei S, Capdevila JH
(2001) J Vasc Res 38: 247-55 - Epoxyeicosatrienoic acids and glucose homeostasis in mice and men.
Luther JM, Brown NJ
(2016) Prostaglandins Other Lipid Mediat 125: 2-7 - Arachidonic acid epoxygenase: structural characterization and quantification of epoxyeicosatrienoates in plasma.
Karara A, Wei S, Spady D, Swift L, Capdevila JH, Falck JR
(1992) Biochem Biophys Res Commun 182: 1320-5 - Cyclooxygenase-derived metabolites of 8,9-epoxyeicosatrienoic acid are potent mitogens for cultured rat glomerular mesangial cells.
Homma T, Zhang JY, Shimizu T, Prakash C, Blair IA, Harris RC
(1993) Biochem Biophys Res Commun 191: 282-8
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.
