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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to GTP-Binding Protein alpha Subunits, Gi-Go are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for GTP-Binding Protein alpha Subunits, Gi-Go.
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Publications
- Opposing effects of beta(1)- and beta(2)-adrenergic receptors on cardiac myocyte apoptosis : role of a pertussis toxin-sensitive G protein.
Communal C, Singh K, Sawyer DB, Colucci WS
(1999) Circulation 100: 2210-2 - Hepatic Gi signaling regulates whole-body glucose homeostasis.
Rossi M, Zhu L, McMillin SM, Pydi SP, Jain S, Wang L, Cui Y, Lee RJ, Cohen AH, Kaneto H, Birnbaum MJ, Ma Y, Rotman Y, Liu J, Cyphert TJ, Finkel T, McGuinness OP, Wess J
(2018) J Clin Invest 128: 746-759 - Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins.
Oldham WM, Van Eps N, Preininger AM, Hubbell WL, Hamm HE
(2007) Proc Natl Acad Sci U S A 104: 7927-32 - GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation.
Damian M, Pons V, Renault P, M'Kadmi C, Delort B, Hartmann L, Kaya AI, Louet M, Gagne D, Ben Haj Salah K, Denoyelle S, Ferry G, Boutin JA, Wagner R, Fehrentz JA, Martinez J, Marie J, Floquet N, Galès C, Mary S, Hamm HE, Banères JL
(2018) Proc Natl Acad Sci U S A 115: 4501-4506 - FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions.
Serezani CH, Aronoff DM, Sitrin RG, Peters-Golden M
(2009) Blood 114: 3316-24 - Physiological roles for neuromodulation via G GPCRs working through Gβγ-SNARE interaction.
Hamm HE, Alford ST
(2020) Neuropsychopharmacology 45: 221 - Structure of the GDP-Pi complex of Gly203-->Ala gialpha1: a mimic of the ternary product complex of galpha-catalyzed GTP hydrolysis.
Berghuis AM, Lee E, Raw AS, Gilman AG, Sprang SR
(1996) Structure 4: 1277-90 - TGFbeta regulates the expression of G alpha(i2) via an effect on the localization of ras.
Ward SM, Gadbut AP, Tang D, Papageorge AG, Wu L, Li G, Barnett JV, Galper JB
(2002) J Mol Cell Cardiol 34: 1217-26 - Suboptimal activation of protease-activated receptors enhances alpha2beta1 integrin-mediated platelet adhesion to collagen.
Marjoram RJ, Voss B, Pan Y, Dickeson SK, Zutter MM, Hamm HE, Santoro SA
(2009) J Biol Chem 284: 34640-7 - Closely related G-protein-coupled receptors use multiple and distinct domains on G-protein alpha-subunits for selective coupling.
Slessareva JE, Ma H, Depree KM, Flood LA, Bae H, Cabrera-Vera TM, Hamm HE, Graber SG
(2003) J Biol Chem 278: 50530-6 - Thrombin modulates the expression of a set of genes including thrombospondin-1 in human microvascular endothelial cells.
McLaughlin JN, Mazzoni MR, Cleator JH, Earls L, Perdigoto AL, Brooks JD, Muldowney JA, Vaughan DE, Hamm HE
(2005) J Biol Chem 280: 22172-80 - Characterization of a rabbit kidney prostaglandin F(2{alpha}) receptor exhibiting G(i)-restricted signaling that inhibits water absorption in the collecting duct.
Hébert RL, Carmosino M, Saito O, Yang G, Jackson CA, Qi Z, Breyer RM, Natarajan C, Hata AN, Zhang Y, Guan Y, Breyer MD
(2005) J Biol Chem 280: 35028-37 - Activation mechanism of Gi and Go by reactive oxygen species.
Nishida M, Schey KL, Takagahara S, Kontani K, Katada T, Urano Y, Nagano T, Nagao T, Kurose H
(2002) J Biol Chem 277: 9036-42 - A Conserved Hydrophobic Core in Gαi1 Regulates G Protein Activation and Release from Activated Receptor.
Kaya AI, Lokits AD, Gilbert JA, Iverson TM, Meiler J, Hamm HE
(2016) J Biol Chem 291: 19674-86 - A transient interaction between the phosphate binding loop and switch I contributes to the allosteric network between receptor and nucleotide in Gαi1.
Thaker TM, Sarwar M, Preininger AM, Hamm HE, Iverson TM
(2014) J Biol Chem 289: 11331-11341 - PAR1, but not PAR4, activates human platelets through a Gi/o/phosphoinositide-3 kinase signaling axis.
Voss B, McLaughlin JN, Holinstat M, Zent R, Hamm HE
(2007) Mol Pharmacol 71: 1399-406 - Gβγ Binds to the Extreme C Terminus of SNAP25 to Mediate the Action of Gi/o-Coupled G Protein-Coupled Receptors.
Zurawski Z, Rodriguez S, Hyde K, Alford S, Hamm HE
(2016) Mol Pharmacol 89: 75-83 - A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors.
Niswender CM, Johnson KA, Luo Q, Ayala JE, Kim C, Conn PJ, Weaver CD
(2008) Mol Pharmacol 73: 1213-24 - Respiratory syncytial virus infection reduces beta2-adrenergic responses in human airway smooth muscle.
Moore PE, Cunningham G, Calder MM, DeMatteo AD, Peeples ME, Summar ML, Peebles RS
(2006) Am J Respir Cell Mol Biol 35: 559-64 - Ca2+-calmodulin and janus kinase 2 are required for activation of sodium-proton exchange by the Gi-coupled 5-hydroxytryptamine 1a receptor.
Turner JH, Garnovskaya MN, Coaxum SD, Vlasova TM, Yakutovich M, Lefler DM, Raymond JR
(2007) J Pharmacol Exp Ther 320: 314-22 - Major sperm protein signaling promotes oocyte microtubule reorganization prior to fertilization in Caenorhabditis elegans.
Harris JE, Govindan JA, Yamamoto I, Schwartz J, Kaverina I, Greenstein D
(2006) Dev Biol 299: 105-21 - Functional capabilities of an N-formyl peptide receptor-G(alpha)(i)(2) fusion protein: assemblies with G proteins and arrestins.
Shi M, Bennett TA, Cimino DF, Maestas DC, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER
(2003) Biochemistry 42: 7283-93 - Myristoylation exerts direct and allosteric effects on Gα conformation and dynamics in solution.
Preininger AM, Kaya AI, Gilbert JA, Busenlehner LS, Armstrong RN, Hamm HE
(2012) Biochemistry 51: 1911-24 - The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution.
Preininger AM, Van Eps N, Yu NJ, Medkova M, Hubbell WL, Hamm HE
(2003) Biochemistry 42: 7931-41 - Helix dipole movement and conformational variability contribute to allosteric GDP release in Galphai subunits.
Preininger AM, Funk MA, Oldham WM, Meier SM, Johnston CA, Adhikary S, Kimple AJ, Siderovski DP, Hamm HE, Iverson TM
(2009) Biochemistry 48: 2630-42 - Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation.
Medkova M, Preininger AM, Yu NJ, Hubbell WL, Hamm HE
(2002) Biochemistry 41: 9962-72 - Trp fluorescence reveals an activation-dependent cation-pi interaction in the Switch II region of Galphai proteins.
Hamm HE, Meier SM, Liao G, Preininger AM
(2009) Protein Sci 18: 2326-35 - Regulation of cAMP levels in area CA1 of hippocampus by Gi/o-coupled receptors is stimulus dependent in mice.
Vanhoose AM, Ritchie MD, Winder DG
(2004) Neurosci Lett 370: 80-3 - G alpha t/G alpha i1 chimeras used to define structural basis of specific functions of G alpha t.
Skiba NP, Thomas TO, Hamm HE
(2000) Methods Enzymol 315: 502-24 - Fluorescent probes as indicators of conformation changes in transducin on activation.
Yang CS, Skiba NP, Mazzoni MR, Thomas TO, Hamm HE
(2000) Methods Enzymol 315: 490-502 - Use of peptides-on-plasmids combinatorial library to identify high-affinity peptides that bind rhodopsin.
Gilchrist A, Li A, Hamm HE
(2000) Methods Enzymol 315: 388-404
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