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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Protein Interaction Domains and Motifs are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Protein Interaction Domains and Motifs.
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Publications
- IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors.
Jameson KL, Mazur PK, Zehnder AM, Zhang J, Zarnegar B, Sage J, Khavari PA
(2013) Nat Med 19: 626-630 - Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Cale EM, Gorman J, Radakovich NA, Crooks ET, Osawa K, Tong T, Li J, Nagarajan R, Ozorowski G, Ambrozak DR, Asokan M, Bailer RT, Bennici AK, Chen X, Doria-Rose NA, Druz A, Feng Y, Joyce MG, Louder MK, O'Dell S, Oliver C, Pancera M, Connors M, Hope TJ, Kepler TB, Wyatt RT, Ward AB, Georgiev IS, Kwong PD, Mascola JR, Binley JM
(2017) Immunity 46: 777-791.e10 - Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses.
Thornburg NJ, Nannemann DP, Blum DL, Belser JA, Tumpey TM, Deshpande S, Fritz GA, Sapparapu G, Krause JC, Lee JH, Ward AB, Lee DE, Li S, Winarski KL, Spiller BW, Meiler J, Crowe JE
(2013) J Clin Invest 123: 4405-9 - Integrative network analysis reveals molecular mechanisms of blood pressure regulation.
Huan T, Meng Q, Saleh MA, Norlander AE, Joehanes R, Zhu J, Chen BH, Zhang B, Johnson AD, Ying S, Courchesne P, Raghavachari N, Wang R, Liu P, International Consortium for Blood Pressure GWAS (ICBP), O'Donnell CJ, Vasan R, Munson PJ, Madhur MS, Harrison DG, Yang X, Levy D
(2015) Mol Syst Biol 11: 799 - Novel genes exhibit distinct patterns of function acquisition and network integration.
Capra JA, Pollard KS, Singh M
(2010) Genome Biol 11: R127 - EGFR Kinase Domain Duplication (EGFR-KDD) Is a Novel Oncogenic Driver in Lung Cancer That Is Clinically Responsive to Afatinib.
Gallant JN, Sheehan JH, Shaver TM, Bailey M, Lipson D, Chandramohan R, Red Brewer M, York SJ, Kris MG, Pietenpol JA, Ladanyi M, Miller VA, Ali SM, Meiler J, Lovly CM
(2015) Cancer Discov 5: 1155-63 - Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity.
Smith TK, Hager HA, Francis R, Kilkenny DM, Lo CW, Bader DM
(2008) Proc Natl Acad Sci U S A 105: 8298-303 - Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin.
Zhuang T, Chen Q, Cho MK, Vishnivetskiy SA, Iverson TM, Gurevich VV, Sanders CR
(2013) Proc Natl Acad Sci U S A 110: 942-7 - Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase.
Vaithiyalingam S, Warren EM, Eichman BF, Chazin WJ
(2010) Proc Natl Acad Sci U S A 107: 13684-9 - Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression.
Wang L, Man N, Sun XJ, Tan Y, García-Cao M, Cao MG, Liu F, Hatlen M, Xu H, Huang G, Mattlin M, Mehta A, Rampersaud E, Benezra R, Nimer SD
(2015) Blood 126: 640-50 - Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction.
Corral-Rodríguez MÁ, Bock PE, Hernández-Carvajal E, Gutiérrez-Gallego R, Fuentes-Prior P
(2011) Blood 117: 7164-73 - Quaternary epitopes of α345(IV) collagen initiate Alport post-transplant anti-GBM nephritis.
Olaru F, Luo W, Wang XP, Ge L, Hertz JM, Kashtan CE, Sado Y, Segal Y, Hudson BG, Borza DB
(2013) J Am Soc Nephrol 24: 889-95 - Proapoptotic Bid mediates the Atr-directed DNA damage response to replicative stress.
Liu Y, Bertram CC, Shi Q, Zinkel SS
(2011) Cell Death Differ 18: 841-52 - Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins.
Guilliam TA, Jozwiakowski SK, Ehlinger A, Barnes RP, Rudd SG, Bailey LJ, Skehel JM, Eckert KA, Chazin WJ, Doherty AJ
(2015) Nucleic Acids Res 43: 1056-68 - Antitumor activity of cell-permeable RUNX3 protein in gastric cancer cells.
Lim J, Duong T, Do N, Do P, Kim J, Kim H, El-Rifai W, Ruley HE, Jo D
(2013) Clin Cancer Res 19: 680-90 - A proteomics analysis of yeast Mot1p protein-protein associations: insights into mechanism.
Arnett DR, Jennings JL, Tabb DL, Link AJ, Weil PA
(2008) Mol Cell Proteomics 7: 2090-106 - HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.
Sivakumaran V, Stanley BA, Tocchetti CG, Ballin JD, Caceres V, Zhou L, Keceli G, Rainer PP, Lee DI, Huke S, Ziolo MT, Kranias EG, Toscano JP, Wilson GM, O'Rourke B, Kass DA, Mahaney JE, Paolocci N
(2013) Antioxid Redox Signal 19: 1185-97 - Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration.
Oppelt A, Lobert VH, Haglund K, Mackey AM, Rameh LE, Liestøl K, Schink KO, Pedersen NM, Wenzel EM, Haugsten EM, Brech A, Rusten TE, Stenmark H, Wesche J
(2013) EMBO Rep 14: 57-64 - Structure of Epstein-Barr virus glycoprotein 42 suggests a mechanism for triggering receptor-activated virus entry.
Kirschner AN, Sorem J, Longnecker R, Jardetzky TS
(2009) Structure 17: 223-33 - Integrated Structural Biology for α-Helical Membrane Protein Structure Determination.
Xia Y, Fischer AW, Teixeira P, Weiner B, Meiler J
(2018) Structure 26: 657-666.e2 - The NTD-CTD intersubunit interface plays a critical role in assembly and stabilization of the HIV-1 capsid.
Yufenyuy EL, Aiken C
(2013) Retrovirology 10: 29 - The STAT5b Linker Domain Mediates the Selectivity of Catechol Bisphosphates for STAT5b over STAT5a.
Gräb J, Berg A, Blechschmidt L, Klüver B, Rubner S, Fu DY, Meiler J, Gräber M, Berg T
(2019) ACS Chem Biol 14: 796-805 - LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding.
Layer JH, Alford CE, McDonald WH, Davé UP
(2016) Mol Cell Biol 36: 488-506 - BID binds to replication protein A and stimulates ATR function following replicative stress.
Liu Y, Vaithiyalingam S, Shi Q, Chazin WJ, Zinkel SS
(2011) Mol Cell Biol 31: 4298-309 - Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain.
Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, Mostafa H, Kozakewich H, Kearney D, Cahill JB, Whitt M, Bilic M, Margraf L, Charles A, Goldblatt J, Gibson K, Lantz PE, Garvin AJ, Petty J, Kiblawi Z, Zuppan C, McConkie-Rosell A, McDonald MT, Peterson-Carmichael SL, Gaede JT, Shivanna B, Schady D, Friedlich PS, Hays SR, Palafoll IV, Siebers-Renelt U, Bohring A, Finn LS, Siebert JR, Galambos C, Nguyen L, Riley M, Chassaing N, Vigouroux A, Rocha G, Fernandes S, Brumbaugh J, Roberts K, Ho-Ming L, Lo IF, Lam S, Gerychova R, Jezova M, Valaskova I, Fellmann F, Afshar K, Giannoni E, Muhlethaler V, Liang J, Beckmann JS, Lioy J, Deshmukh H, Srinivasan L, Swarr DT, Sloman M, Shaw-Smith C, van Loon RL, Hagman C, Sznajer Y, Barrea C, Galant C, Detaille T, Wambach JA, Cole FS, Hamvas A, Prince LS, Diderich KE, Brooks AS, Verdijk RM, Ravindranathan H, Sugo E, Mowat D, Baker ML, Langston C, Welty S, Stankiewicz P
(2013) Hum Mutat 34: 801-11 - Mapping structural landmarks, ligand binding sites, and missense mutations to the collagen IV heterotrimers predicts major functional domains, novel interactions, and variation in phenotypes in inherited diseases affecting basement membranes.
Parkin JD, San Antonio JD, Pedchenko V, Hudson B, Jensen ST, Savige J
(2011) Hum Mutat 32: 127-43 - Mechanisms of receptor tyrosine kinase activation in cancer.
Du Z, Lovly CM
(2018) Mol Cancer 17: 58 - Structural Insights into Reovirus σ1 Interactions with Two Neutralizing Antibodies.
Dietrich MH, Ogden KM, Katen SP, Reiss K, Sutherland DM, Carnahan RH, Goff M, Cooper T, Dermody TS, Stehle T
(2017) J Virol 91: - Rotavirus Species B Encodes a Functional Fusion-Associated Small Transmembrane Protein.
Diller JR, Parrington HM, Patton JT, Ogden KM
(2019) J Virol 93: - A novel experimental strategy to assess the metabolic effects of selective activation of a G(q)-coupled receptor in hepatocytes in vivo.
Li JH, Jain S, McMillin SM, Cui Y, Gautam D, Sakamoto W, Lu H, Jou W, McGuinness OP, Gavrilova O, Wess J
(2013) Endocrinology 154: 3539-51 - GABRB3 mutation, G32R, associated with childhood absence epilepsy alters α1β3γ2L γ-aminobutyric acid type A (GABAA) receptor expression and channel gating.
Gurba KN, Hernandez CC, Hu N, Macdonald RL
(2012) J Biol Chem 287: 12083-97 - Use of a neutralizing antibody helps identify structural features critical for binding of toxin TcdA to the host cell surface.
Kroh HK, Chandrasekaran R, Rosenthal K, Woods R, Jin X, Ohi MD, Nyborg AC, Rainey GJ, Warrener P, Spiller BW, Lacy DB
(2017) J Biol Chem 292: 14401-14412 - Structural and biochemical analyses reveal insights into covalent flavinylation of the Complex II homolog quinol:fumarate reductase.
Starbird CA, Maklashina E, Sharma P, Qualls-Histed S, Cecchini G, Iverson TM
(2017) J Biol Chem 292: 12921-12933 - Human DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress.
Guler GD, Liu H, Vaithiyalingam S, Arnett DR, Kremmer E, Chazin WJ, Fanning E
(2012) J Biol Chem 287: 6469-81 - The C-terminal region of A-kinase anchor protein 350 (AKAP350A) enables formation of microtubule-nucleation centers and interacts with pericentriolar proteins.
Kolobova E, Roland JT, Lapierre LA, Williams JA, Mason TA, Goldenring JR
(2017) J Biol Chem 292: 20394-20409 - Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes.
Zurawski Z, Page B, Chicka MC, Brindley RL, Wells CA, Preininger AM, Hyde K, Gilbert JA, Cruz-Rodriguez O, Currie KPM, Chapman ER, Alford S, Hamm HE
(2017) J Biol Chem 292: 12165-12177 - The adaptor protein GULP promotes Jedi-1-mediated phagocytosis through a clathrin-dependent mechanism.
Sullivan CS, Scheib JL, Ma Z, Dang RP, Schafer JM, Hickman FE, Brodsky FM, Ravichandran KS, Carter BD
(2014) Mol Biol Cell 25: 1925-36 - Interaction of members of the heat shock protein-70 family with the macrophage mannose receptor.
Yang S, Vigerust DJ, Shepherd VL
(2013) J Leukoc Biol 93: 529-36 - Gβγ inhibits exocytosis via interaction with critical residues on soluble N-ethylmaleimide-sensitive factor attachment protein-25.
Wells CA, Zurawski Z, Betke KM, Yim YY, Hyde K, Rodriguez S, Alford S, Hamm HE
(2012) Mol Pharmacol 82: 1136-49 - Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase.
Wang Z, Tacchelly-Benites O, Yang E, Thorne CA, Nojima H, Lee E, Ahmed Y
(2016) Genetics 203: 269-81
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