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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Quinoxalines are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Quinoxalines.
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- Targeting Plasmodium PI(4)K to eliminate malaria.
McNamara CW, Lee MC, Lim CS, Lim SH, Roland J, Simon O, Yeung BK, Chatterjee AK, McCormack SL, Manary MJ, Zeeman AM, Dechering KJ, Kumar TS, Henrich PP, Gagaring K, Ibanez M, Kato N, Kuhen KL, Fischli C, Nagle A, Rottmann M, Plouffe DM, Bursulaya B, Meister S, Rameh L, Trappe J, Haasen D, Timmerman M, Sauerwein RW, Suwanarusk R, Russell B, Renia L, Nosten F, Tully DC, Kocken CH, Glynne RJ, Bodenreider C, Fidock DA, Diagana TT, Winzeler EA
(2013) Nature 504: 248-253 - Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer.
Formisano L, Lu Y, Servetto A, Hanker AB, Jansen VM, Bauer JA, Sudhan DR, Guerrero-Zotano AL, Croessmann S, Guo Y, Ericsson PG, Lee KM, Nixon MJ, Schwarz LJ, Sanders ME, Dugger TC, Cruz MR, Behdad A, Cristofanilli M, Bardia A, O'Shaughnessy J, Nagy RJ, Lanman RB, Solovieff N, He W, Miller M, Su F, Shyr Y, Mayer IA, Balko JM, Arteaga CL
(2019) Nat Commun 10: 1373 - Feedback upregulation of HER3 (ErbB3) expression and activity attenuates antitumor effect of PI3K inhibitors.
Chakrabarty A, Sánchez V, Kuba MG, Rinehart C, Arteaga CL
(2012) Proc Natl Acad Sci U S A 109: 2718-23 - BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways.
Yang J, Amiri KI, Burke JR, Schmid JA, Richmond A
(2006) Clin Cancer Res 12: 950-60 - Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy.
Yang J, Zaja-Milatovic S, Thu YM, Lee F, Smykla R, Richmond A
(2009) Mol Cancer Ther 8: 636-47 - Duration and intensity of NF-kappaB activity determine the severity of endotoxin-induced acute lung injury.
Everhart MB, Han W, Sherrill TP, Arutiunov M, Polosukhin VV, Burke JR, Sadikot RT, Christman JW, Yull FE, Blackwell TS
(2006) J Immunol 176: 4995-5005 - Evidence that additional mechanisms to cyclic GMP mediate the decrease in intracellular calcium and relaxation of rabbit aortic smooth muscle to nitric oxide.
Weisbrod RM, Griswold MC, Yaghoubi M, Komalavilas P, Lincoln TM, Cohen RA
(1998) Br J Pharmacol 125: 1695-707 - Well-done meat intake and meat-derived mutagen exposures in relation to breast cancer risk: the Nashville Breast Health Study.
Fu Z, Deming SL, Fair AM, Shrubsole MJ, Wujcik DM, Shu XO, Kelley M, Zheng W
(2011) Breast Cancer Res Treat 129: 919-28 - nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase.
Chetkovich DM, Sweatt JD
(1993) J Neurochem 61: 1933-42 - Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2.
Turesky RJ, Guengerich FP, Guillouzo A, Langouët S
(2002) Mutat Res 506-507: 187-95 - Development of a new genotoxicity test system with Salmonella typhimurium OY1001/1A2 expressing human CYP1A2 and NADPH-P450 reductase.
Aryal P, Yoshikawa K, Terashita T, Guengerich FP, Shimada T, Oda Y
(1999) Mutat Res 442: 113-20 - Calcium-dependent inhibition of synaptosomal serotonin transport by the alpha 2-adrenoceptor agonist 5-bromo-N-[4,5-dihydro-1H-imidazol-2-yl]-6-quinoxalinamine (UK14304).
Ansah TA, Ramamoorthy S, Montañez S, Daws LC, Blakely RD
(2003) J Pharmacol Exp Ther 305: 956-65 - NF-κB inhibition after cecal ligation and puncture reduces sepsis-associated lung injury without altering bacterial host defense.
Li H, Han W, Polosukhin V, Yull FE, Segal BH, Xie CM, Blackwell TS
(2013) Mediators Inflamm 2013: 503213 - Regioselective differences in C(8)- and N-oxidation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by human and rat liver microsomes and cytochromes P450 1A2.
Turesky RJ, Parisod V, Huynh-Ba T, Langouët S, Guengerich FP
(2001) Chem Res Toxicol 14: 901-11 - Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes: 2-amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxification pathway catalyzed by cytochrome P450 1A2.
Langouët S, Welti DH, Kerriguy N, Fay LB, Huynh-Ba T, Markovic J, Guengerich FP, Guillouzo A, Turesky RJ
(2001) Chem Res Toxicol 14: 211-21 - Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
Turesky RJ, Constable A, Richoz J, Varga N, Markovic J, Martin MV, Guengerich FP
(1998) Chem Res Toxicol 11: 925-36 - A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469.
Ramírez J, Kim TW, Liu W, Myers JL, Mirkov S, Owzar K, Watson D, Mulkey F, Gamazon ER, Stock W, Undevia S, Innocenti F, Ratain MJ
(2014) Pharmacogenet Genomics 24: 129-32 - Proteomic exploration of pancreatic islets in mice null for the alpha2A adrenergic receptor.
Hu X, Friedman D, Hill S, Caprioli R, Nicholson W, Powers AC, Hunter L, Limbird LE
(2005) J Mol Endocrinol 35: 73-88 - Kainic acid induces apoptosis in neurons.
Simonian NA, Getz RL, Leveque JC, Konradi C, Coyle JT
(1996) Neuroscience 75: 1047-55 - Regulation of cAMP levels in area CA1 of hippocampus by Gi/o-coupled receptors is stimulus dependent in mice.
Vanhoose AM, Ritchie MD, Winder DG
(2004) Neurosci Lett 370: 80-3 - Metabolism of the food mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes.
Langouët S, Welti DH, Kerriguy N, Fay LB, Guengerich FP, Guillouzo A, Turesky RJ
(2001) Adv Exp Med Biol 500: 459-62
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