Pif1 family helicases suppress genome instability at G-quadruplex motifs. Paeschke K, Bochman ML, Garcia PD, Cejka P, Friedman KL, Kowalczykowski SC, Zakian VA (2013) Nature 497: 458-62 Transgenic HLA-DR alpha faithfully reconstitutes IE-controlled immune functions and induces cross-tolerance to E alpha in E alpha 0 mutant mice. Lawrance SK, Karlsson L, Price J, Quaranta V, Ron Y, Sprent J, Peterson PA (1989) Cell 58: 583-94 Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Smider V, Rathmell WK, Lieber MR, Chu G (1994) Science 266: 288-91 A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. York JD, Odom AR, Murphy R, Ives EB, Wente SR (1999) Science 285: 96-100 The high osmolarity glycerol response (HOG) MAP kinase pathway controls localization of a yeast golgi glycosyltransferase. Reynolds TB, Hopkins BD, Lyons MR, Graham TR (1998) J Cell Biol 143: 935-46 The Schizosaccharomyces pombe cdc5+ gene encodes an essential protein with homology to c-Myb. Ohi R, McCollum D, Hirani B, Den Haese GJ, Zhang X, Burke JD, Turner K, Gould KL (1994) EMBO J 13: 471-83 Yeast casein kinase I homologues: an essential gene pair. Robinson LC, Hubbard EJ, Graves PR, DePaoli-Roach AA, Roach PJ, Kung C, Haas DW, Hagedorn CH, Goebl M, Culbertson MR (1992) Proc Natl Acad Sci U S A 89: 28-32 Use of avian retroviral vectors to introduce transcriptional regulators into mammalian cells for analyses of tumor maintenance. Pao W, Klimstra DS, Fisher GH, Varmus HE (2003) Proc Natl Acad Sci U S A 100: 8764-9 Identification of an epithelial cell receptor responsible for Clostridium difficile TcdB-induced cytotoxicity. LaFrance ME, Farrow MA, Chandrasekaran R, Sheng J, Rubin DH, Lacy DB (2015) Proc Natl Acad Sci U S A 112: 7073-8 The Arabidopsis HOMOLOGY-DEPENDENT GENE SILENCING1 gene codes for an S-adenosyl-L-homocysteine hydrolase required for DNA methylation-dependent gene silencing. Rocha PS, Sheikh M, Melchiorre R, Fagard M, Boutet S, Loach R, Moffatt B, Wagner C, Vaucheret H, Furner I (2005) Plant Cell 17: 404-17 Isolation of an essential Schizosaccharomyces pombe gene, prp31(+), that links splicing and meiosis. Bishop DT, McDonald WH, Gould KL, Forsburg SL (2000) Nucleic Acids Res 28: 2214-20 Mechanisms of oncogene cooperation: activation and inactivation of a growth antagonist. Ragozzino MM, Kuo A, DeGregori J, Kohl N, Ruley HE (1991) Environ Health Perspect 93: 97-103 Two Arabidopsis loci encode novel eukaryotic initiation factor 4E isoforms that are functionally distinct from the conserved plant eukaryotic initiation factor 4E. Patrick RM, Mayberry LK, Choy G, Woodard LE, Liu JS, White A, Mullen RA, Tanavin TM, Latz CA, Browning KS (2014) Plant Physiol 164: 1820-30 The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy. Long AA, Mahapatra CT, Woodruff EA, Rohrbough J, Leung HT, Shino S, An L, Doerge RW, Metzstein MM, Pak WL, Broadie K (2010) J Cell Sci 123: 3303-15 A DNA end-binding factor involved in double-strand break repair and V(D)J recombination. Rathmell WK, Chu G (1994) Mol Cell Biol 14: 4741-8 The conserved carboxy-terminal domain of Saccharomyces cerevisiae TFIID is sufficient to support normal cell growth. Poon D, Schroeder S, Wang CK, Yamamoto T, Horikoshi M, Roeder RG, Weil PA (1991) Mol Cell Biol 11: 4809-21 Adenovirus E1A-mediated negative control of genes activated during F9 differentiation. Young KS, Weigel R, Hiebert S, Nevins JR (1989) Mol Cell Biol 9: 3109-13 Fragments of ATM which have dominant-negative or complementing activity. Morgan SE, Lovly C, Pandita TK, Shiloh Y, Kastan MB (1997) Mol Cell Biol 17: 2020-9 Myb-related Schizosaccharomyces pombe cdc5p is structurally and functionally conserved in eukaryotes. Ohi R, Feoktistova A, McCann S, Valentine V, Look AT, Lipsick JS, Gould KL (1998) Mol Cell Biol 18: 4097-108 Histone folds mediate selective heterodimerization of yeast TAF(II)25 with TFIID components yTAF(II)47 and yTAF(II)65 and with SAGA component ySPT7. Gangloff YG, Sanders SL, Romier C, Kirschner D, Weil PA, Tora L, Davidson I (2001) Mol Cell Biol 21: 1841-53 Yeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression. Gerbasi VR, Weaver CM, Hill S, Friedman DB, Link AJ (2004) Mol Cell Biol 24: 8276-87 Mtg16/Eto2 contributes to murine T-cell development. Hunt A, Fischer M, Engel ME, Hiebert SW (2011) Mol Cell Biol 31: 2544-51 Schizosaccharomyces pombe skp1+ encodes a protein kinase related to mammalian glycogen synthase kinase 3 and complements a cdc14 cytokinesis mutant. Plyte SE, Feoktistova A, Burke JD, Woodgett JR, Gould KL (1996) Mol Cell Biol 16: 179-91 Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants. Errami A, Smider V, Rathmell WK, He DM, Hendrickson EA, Zdzienicka MZ, Chu G (1996) Mol Cell Biol 16: 1519-26 Binding-site interactions between Epstein-Barr virus fusion proteins gp42 and gH/gL reveal a peptide that inhibits both epithelial and B-cell membrane fusion. Kirschner AN, Lowrey AS, Longnecker R, Jardetzky TS (2007) J Virol 81: 9216-29 The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication. Graham RL, Sims AC, Brockway SM, Baric RS, Denison MR (2005) J Virol 79: 13399-411 Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin. McClain MS, Iwamoto H, Cao P, Vinion-Dubiel AD, Li Y, Szabo G, Shao Z, Cover TL (2003) J Biol Chem 278: 12101-8 Communication between the ATPase and cleavage/religation domains of human topoisomerase IIalpha. Bjergbaek L, Kingma P, Nielsen IS, Wang Y, Westergaard O, Osheroff N, Andersen AH (2000) J Biol Chem 275: 13041-8 The human homolog of the rat inositol phosphate multikinase is an inositol 1,3,4,6-tetrakisphosphate 5-kinase. Chang SC, Miller AL, Feng Y, Wente SR, Majerus PW (2002) J Biol Chem 277: 43836-43 Genetic complementation in yeast reveals functional similarities between the catalytic subunits of mammalian signal peptidase complex. Liang H, VanValkenburgh C, Chen X, Mullins C, Van Kaer L, Green N, Fang H (2003) J Biol Chem 278: 50932-9 Functional analysis of the TFIID-specific yeast TAF4 (yTAF(II)48) reveals an unexpected organization of its histone-fold domain. Thuault S, Gangloff YG, Kirchner J, Sanders S, Werten S, Romier C, Weil PA, Davidson I (2002) J Biol Chem 277: 45510-7 Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway. Miller AL, Suntharalingam M, Johnson SL, Audhya A, Emr SD, Wente SR (2004) J Biol Chem 279: 51022-32 Control of protein and sterol trafficking by antagonistic activities of a type IV P-type ATPase and oxysterol binding protein homologue. Muthusamy BP, Raychaudhuri S, Natarajan P, Abe F, Liu K, Prinz WA, Graham TR (2009) Mol Biol Cell 20: 2920-31 Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry. Jodoin JN, Shboul M, Sitaram P, Zein-Sabatto H, Reversade B, Lee E, Lee LA (2012) Mol Biol Cell 23: 4713-24 Characterization of novel mutations at the Schizosaccharomyces pombe cdc2 regulatory phosphorylation site, tyrosine 15. Gould KL, Feoktistova A (1996) Mol Biol Cell 7: 1573-86 The maternal nudel protein of Drosophila has two distinct roles important for embryogenesis. Hong CC, Hashimoto C (1996) Genetics 143: 1653-61 Fission yeast cdc24(+) encodes a novel replication factor required for chromosome integrity. Gould KL, Burns CG, Feoktistova A, Hu CP, Pasion SG, Forsburg SL (1998) Genetics 149: 1221-33 An arf1Delta synthetic lethal screen identifies a new clathrin heavy chain conditional allele that perturbs vacuolar protein transport in Saccharomyces cerevisiae. Chen CY, Graham TR (1998) Genetics 150: 577-89 Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation. Schwarz JK, Lovly CM, Piwnica-Worms H (2003) Mol Cancer Res 1: 598-609 Suppression of tumorigenicity, but not invasion, in glioblastoma/HeLa cell hybrids. Ess K, Chen H, Kier A, Brackenbury R (1995) J Cell Physiol 162: 341-7
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