Keyword Connections

•  Antonis Hatzopoulos
•  Charles Hong

•  Douglas Mortlock
•  Ela Knapik

•  James Patton

Resources

• No matching connections

Communities

• Hatzopoulos Lab
• Hong Lab
• Mortlock Lab

Publications

• Activin- and Nodal-related factors control antero-posterior patterning of the zebrafish embryo.
  Thisse B, Wright CV, Thisse C
  (2000) Nature 403: 425-8
• Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling.
  Sampath K, Rubinstein AL, Cheng AM, Liang JO, Fekany K, Solnica-Krezel L, Korzh V, Halpern ME, Wright CV
  (1998) Nature 395: 185-9
• Active medulloblastoma enhancers reveal subgroup-specific cellular origins.
  Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz HJ, Worst BC, Ju B, Orr BA, Zeid R, Polaski DR, Segura-Wang M, Waszak SM, Jones DT, Kool M, Hovestadt V, Buchhalter I, Sieber L, Johann P, Chavez L, Gröschel S, Ryzhova M, Korshunov A, Chen W, Chizhikov VV, Millen KJ, Amstislavskiy V, Lehrach H, Yaspo ML, Eils R, Lichter P, Korbel JO, Pfister SM, Bradner JE, Northcott PA
  (2016) Nature 530: 57-62
• Obesity-associated variants within FTO form long-range functional connections with IRX3.
  Smemo S, Tena JJ, Kim KH, Gamazon ER, Sakabe NJ, Gómez-Marín C, Aneas I, Credidio FL, Sobreira DR, Wasserman NF, Lee JH, Puviindran V, Tam D, Shen M, Son JE, Vakili NA, Sung HK, Naranjo S, Acemel RD, Manzanares M, Nagy A, Cox NJ, Hui CC, Gomez-Skarmeta JL, Nóbrega MA
  (2014) Nature 507: 371-5
• Secretory COPII coat component Sec23a is essential for craniofacial chondrocyte maturation.
  Lang MR, Lapierre LA, Frotscher M, Goldenring JR, Knapik EW
  (2006) Nat Genet 38: 1198-203
• Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development.
  Golling G, Amsterdam A, Sun Z, Antonelli M, Maldonado E, Chen W, Burgess S, Haldi M, Artzt K, Farrington S, Lin SY, Nissen RM, Hopkins N
  (2002) Nat Genet 31: 135-40
• Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling.
  Ericson J, Rashbass P, Schedl A, Brenner-Morton S, Kawakami A, van Heyningen V, Jessell TM, Briscoe J
  (1997) Cell 90: 169-80
• Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance.
  van der Klaauw AA, Croizier S, Mendes de Oliveira E, Stadler LKJ, Park S, Kong Y, Banton MC, Tandon P, Hendricks AE, Keogh JM, Riley SE, Papadia S, Henning E, Bounds R, Bochukova EG, Mistry V, O'Rahilly S, Simerly RB, INTERVAL, UK10K Consortium, Minchin JEN, Barroso I, Jones EY, Bouret SG, Farooqi IS
  (2019) Cell 176: 729-742.e18
• Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish.
  Sebag JA, Zhang C, Hinkle PM, Bradshaw AM, Cone RD
  (2013) Science 341: 278-81
• Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies.
  Unlu G, Qi X, Gamazon ER, Melville DB, Patel N, Rushing AR, Hashem M, Al-Faifi A, Chen R, Li B, Cox NJ, Alkuraya FS, Knapik EW
  (2020) Nat Med 26: 98-109
• The perivascular niche regulates breast tumour dormancy.
  Ghajar CM, Peinado H, Mori H, Matei IR, Evason KJ, Brazier H, Almeida D, Koller A, Hajjar KA, Stainier DY, Chen EI, Lyden D, Bissell MJ
  (2013) Nat Cell Biol 15: 807-17
• Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport.
  Jin D, Ni TT, Sun J, Wan H, Amack JD, Yu G, Fleming J, Chiang C, Li W, Papierniak A, Cheepala S, Conseil G, Cole SP, Zhou B, Drummond IA, Schuetz JD, Malicki J, Zhong TP
  (2014) Nat Cell Biol 16: 841-51
• Distinct signalling pathways regulate sprouting angiogenesis from the dorsal aorta and the axial vein.
  Wiley DM, Kim JD, Hao J, Hong CC, Bautch VL, Jin SW
  (2011) Nat Cell Biol 13: 686-92
• Six3 represses nodal activity to establish early brain asymmetry in zebrafish.
  Inbal A, Kim SH, Shin J, Solnica-Krezel L
  (2007) Neuron 55: 407-15
• Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts.
  Salic A, Lee E, Mayer L, Kirschner MW
  (2000) Mol Cell 5: 523-32
• Retinal network adaptation to bright light requires tyrosinase.
  Page-McCaw PS, Chung SC, Muto A, Roeser T, Staub W, Finger-Baier KC, Korenbrot JI, Baier H
  (2004) Nat Neurosci 7: 1329-36
• Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation.
  Sinner MF, Tucker NR, Lunetta KL, Ozaki K, Smith JG, Trompet S, Bis JC, Lin H, Chung MK, Nielsen JB, Lubitz SA, Krijthe BP, Magnani JW, Ye J, Gollob MH, Tsunoda T, Müller-Nurasyid M, Lichtner P, Peters A, Dolmatova E, Kubo M, Smith JD, Psaty BM, Smith NL, Jukema JW, Chasman DI, Albert CM, Ebana Y, Furukawa T, Macfarlane PW, Harris TB, Darbar D, Dörr M, Holst AG, Svendsen JH, Hofman A, Uitterlinden AG, Gudnason V, Isobe M, Malik R, Dichgans M, Rosand J, Van Wagoner DR, METASTROKE Consortium, AFGen Consortium, Benjamin EJ, Milan DJ, Melander O, Heckbert SR, Ford I, Liu Y, Barnard J, Olesen MS, Stricker BH, Tanaka T, Kääb S, Ellinor PT
  (2014) Circulation 130: 1225-35
• Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization.
  Milan DJ, Kim AM, Winterfield JR, Jones IL, Pfeufer A, Sanna S, Arking DE, Amsterdam AH, Sabeh KM, Mably JD, Rosenbaum DS, Peterson RT, Chakravarti A, Kääb S, Roden DM, MacRae CA
  (2009) Circulation 120: 553-9
• Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.
  Dean ED, Li M, Prasad N, Wisniewski SN, Von Deylen A, Spaeth J, Maddison L, Botros A, Sedgeman LR, Bozadjieva N, Ilkayeva O, Coldren A, Poffenberger G, Shostak A, Semich MC, Aamodt KI, Phillips N, Yan H, Bernal-Mizrachi E, Corbin JD, Vickers KC, Levy SE, Dai C, Newgard C, Gu W, Stein R, Chen W, Powers AC
  (2017) Cell Metab 25: 1362-1373.e5
• AgRP and POMC neurons are hypophysiotropic and coordinately regulate multiple endocrine axes in a larval teleost.
  Zhang C, Forlano PM, Cone RD
  (2012) Cell Metab 15: 256-64
• High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.
  Varshney GK, Pei W, LaFave MC, Idol J, Xu L, Gallardo V, Carrington B, Bishop K, Jones M, Li M, Harper U, Huang SC, Prakash A, Chen W, Sood R, Ledin J, Burgess SM
  (2015) Genome Res 25: 1030-42
• Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism.
  Yu PB, Hong CC, Sachidanandan C, Babitt JL, Deng DY, Hoyng SA, Lin HY, Bloch KD, Peterson RT
  (2008) Nat Chem Biol 4: 33-41
• Spatial regionalization and heterochrony in the formation of adult pallial neural stem cells.
  Dirian L, Galant S, Coolen M, Chen W, Bedu S, Houart C, Bally-Cuif L, Foucher I
  (2014) Dev Cell 30: 123-36
• WNT signals are required for the initiation of hair follicle development.
  Andl T, Reddy ST, Gaddapara T, Millar SE
  (2002) Dev Cell 2: 643-53
• Inositol polyphosphates regulate zebrafish left-right asymmetry.
  Sarmah B, Latimer AJ, Appel B, Wente SR
  (2005) Dev Cell 9: 133-45
• Mechanisms of left-right asymmetry: what's right and what's left?
  Wright CV
  (2001) Dev Cell 1: 179-86
• Fishing for biliary atresia susceptibility genes.
  Miethke AG, Huppert SS
  (2013) Gastroenterology 144: 878-81
• Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer.
  Li C, Ma H, Wang Y, Cao Z, Graves-Deal R, Powell AE, Starchenko A, Ayers GD, Washington MK, Kamath V, Desai K, Gerdes MJ, Solnica-Krezel L, Coffey RJ
  (2014) J Clin Invest 124: 2172-87
• Head and trunk in zebrafish arise via coinhibition of BMP signaling by bozozok and chordino.
  Gonzalez EM, Fekany-Lee K, Carmany-Rampey A, Erter C, Topczewski J, Wright CV, Solnica-Krezel L
  (2000) Genes Dev 14: 3087-92
• Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming.
  Papizan JB, Singer RA, Tschen SI, Dhawan S, Friel JM, Hipkens SB, Magnuson MA, Bhushan A, Sussel L
  (2011) Genes Dev 25: 2291-305