An RNA-export mediator with an essential nuclear export signal. Murphy R, Wente SR (1996) Nature 383: 357-60 Dynamic nuclear pore complexes: life on the edge. Tran EJ, Wente SR (2006) Cell 125: 1041-53 The mRNA export factor Gle1 and inositol hexakisphosphate regulate distinct stages of translation. Bolger TA, Folkmann AW, Tran EJ, Wente SR (2008) Cell 134: 624-33 A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. York JD, Odom AR, Murphy R, Ives EB, Wente SR (1999) Science 285: 96-100 Crossing the nuclear envelope: hierarchical regulation of nucleocytoplasmic transport. Terry LJ, Shows EB, Wente SR (2007) Science 318: 1412-6 Inositol hexakisphosphate and Gle1 activate the DEAD-box protein Dbp5 for nuclear mRNA export. Alcázar-Román AR, Tran EJ, Guo S, Wente SR (2006) Nat Cell Biol 8: 711-6 Minimal nuclear pore complexes define FG repeat domains essential for transport. Strawn LA, Shen T, Shulga N, Goldfarb DS, Wente SR (2004) Nat Cell Biol 6: 197-206 Peering through the pore: nuclear pore complex structure, assembly, and function. Suntharalingam M, Wente SR (2003) Dev Cell 4: 775-89 The Plk1 Piece of the Nuclear Envelope Disassembly Puzzle. Dawson TR, Wente SR (2017) Dev Cell 43: 115-117 The Dbp5 cycle at the nuclear pore complex during mRNA export I: dbp5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup159 and Gle1. Hodge CA, Tran EJ, Noble KN, Alcazar-Roman AR, Ben-Yishay R, Scarcelli JJ, Folkmann AW, Shav-Tal Y, Wente SR, Cole CN (2011) Genes Dev 25: 1052-64 The Dbp5 cycle at the nuclear pore complex during mRNA export II: nucleotide cycling and mRNP remodeling by Dbp5 are controlled by Nup159 and Gle1. Noble KN, Tran EJ, Alcázar-Román AR, Hodge CA, Cole CN, Wente SR (2011) Genes Dev 25: 1065-77 Trafficking to uncharted territory of the nuclear envelope. Burns LT, Wente SR (2012) Curr Opin Cell Biol 24: 341-9 A temperature-sensitive NUP116 null mutant forms a nuclear envelope seal over the yeast nuclear pore complex thereby blocking nucleocytoplasmic traffic. Wente SR, Blobel G (1993) J Cell Biol 123: 275-84 A new family of yeast nuclear pore complex proteins. Wente SR, Rout MP, Blobel G (1992) J Cell Biol 119: 705-23 Nuclear mRNA export requires specific FG nucleoporins for translocation through the nuclear pore complex. Terry LJ, Wente SR (2007) J Cell Biol 178: 1121-32 The Ran GTPase cycle is required for yeast nuclear pore complex assembly. Ryan KJ, McCaffery JM, Wente SR (2003) J Cell Biol 160: 1041-53 Simple rules for passive diffusion through the nuclear pore complex. Timney BL, Raveh B, Mironska R, Trivedi JM, Kim SJ, Russel D, Wente SR, Sali A, Rout MP (2016) J Cell Biol 215: 57-76 Altering nuclear pore complex function impacts longevity and mitochondrial function in S. cerevisiae. Lord CL, Timney BL, Rout MP, Wente SR (2015) J Cell Biol 208: 729-44 NUP145 encodes a novel yeast glycine-leucine-phenylalanine-glycine (GLFG) nucleoporin required for nuclear envelope structure. Wente SR, Blobel G (1994) J Cell Biol 125: 955-69 A nuclear export signal in Kap95p is required for both recycling the import factor and interaction with the nucleoporin GLFG repeat regions of Nup116p and Nup100p. Iovine MK, Wente SR (1997) J Cell Biol 137: 797-811 The GLFG repetitive region of the nucleoporin Nup116p interacts with Kap95p, an essential yeast nuclear import factor. Iovine MK, Watkins JL, Wente SR (1995) J Cell Biol 131: 1699-713 The human homologue of Saccharomyces cerevisiae Gle1p is required for poly(A)+ RNA export. Watkins JL, Murphy R, Emtage JL, Wente SR (1998) Proc Natl Acad Sci U S A 95: 6779-84 The nuclear pore complex and nuclear transport. Wente SR, Rout MP (2010) Cold Spring Harb Perspect Biol 2: a000562 Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2. Zheng M, Morgan-Lappe SE, Yang J, Bockbrader KM, Pamarthy D, Thomas D, Fesik SW, Sun Y (2008) Cancer Res 68: 7570-8 The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155. Rayala HJ, Kendirgi F, Barry DM, Majerus PW, Wente SR (2004) Mol Cell Proteomics 3: 145-55 Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis. Brown MF, Leibowitz BJ, Chen D, He K, Zou F, Sobol RW, Beer-Stolz D, Zhang L, Yu J (2015) Cell Death Dis 6: e1729 Defining the essential functional regions of the nucleoporin Nup145p. Emtage JL, Bucci M, Watkins JL, Wente SR (1997) J Cell Sci 110 ( Pt 7): 911-25 Assembly and preferential localization of Nup116p on the cytoplasmic face of the nuclear pore complex by interaction with Nup82p. Ho AK, Shen TX, Ryan KJ, Kiseleva E, Levy MA, Allen TD, Wente SR (2000) Mol Cell Biol 20: 5736-48 From hypothesis to mechanism: uncovering nuclear pore complex links to gene expression. Burns LT, Wente SR (2014) Mol Cell Biol 34: 2114-20 Nup100 regulates replicative life span by mediating the nuclear export of specific tRNAs. Lord CL, Ospovat O, Wente SR (2017) RNA 23: 365-377 Ty3 nuclear entry is initiated by viruslike particle docking on GLFG nucleoporins. Beliakova-Bethell N, Terry LJ, Bilanchone V, DaSilva R, Nagashima K, Wente SR, Sandmeyer S (2009) J Virol 83: 11914-25 HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry. Zhou J, Price AJ, Halambage UD, James LC, Aiken C (2015) J Virol 89: 9068-79 Nup42 and IP coordinate Gle1 stimulation of Dbp5/DDX19B for mRNA export in yeast and human cells. Adams RL, Mason AC, Glass L, Aditi , Wente SR (2017) Traffic 18: 776-790 Prediction of novel Bag-1 homologs based on structure/function analysis identifies Snl1p as an Hsp70 co-chaperone in Saccharomyces cerevisiae. Sondermann H, Ho AK, Listenberger LL, Siegers K, Moarefi I, Wente SR, Hartl FU, Young JC (2002) J Biol Chem 277: 33220-7 Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway. Miller AL, Suntharalingam M, Johnson SL, Audhya A, Emr SD, Wente SR (2004) J Biol Chem 279: 51022-32 Nuclear export of the yeast mRNA-binding protein Nab2 is linked to a direct interaction with Gfd1 and to Gle1 function. Suntharalingam M, Alcázar-Román AR, Wente SR (2004) J Biol Chem 279: 35384-91 GLFG and FxFG nucleoporins bind to overlapping sites on importin-beta. Bayliss R, Littlewood T, Strawn LA, Wente SR, Stewart M (2002) J Biol Chem 277: 50597-606 The GLFG regions of Nup116p and Nup100p serve as binding sites for both Kap95p and Mex67p at the nuclear pore complex. Strawn LA, Shen T, Wente SR (2001) J Biol Chem 276: 6445-52 Control of mRNA export and translation termination by inositol hexakisphosphate requires specific interaction with Gle1. Alcázar-Román AR, Bolger TA, Wente SR (2010) J Biol Chem 285: 16683-92 Gle1 is a multifunctional DEAD-box protein regulator that modulates Ded1 in translation initiation. Bolger TA, Wente SR (2011) J Biol Chem 286: 39750-9
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