An RNA-export mediator with an essential nuclear export signal. Murphy R, Wente SR (1996) Nature 383: 357-60 Removal of the Alu structural domain from signal recognition particle leaves its protein translocation activity intact. Siegel V, Walter P (1986) Nature 320: 81-4 Each of the activities of signal recognition particle (SRP) is contained within a distinct domain: analysis of biochemical mutants of SRP. Siegel V, Walter P (1988) Cell 52: 39-49 A second signal recognition event required for translocation into the endoplasmic reticulum. Siegel V (1995) Cell 82: 167-70 Elongation arrest is not a prerequisite for secretory protein translocation across the microsomal membrane. Siegel V, Walter P (1985) J Cell Biol 100: 1913-21 The affinity of signal recognition particle for presecretory proteins is dependent on nascent chain length. Siegel V, Walter P (1988) EMBO J 7: 1769-75 Molecular cloning of an allene oxide synthase: a cytochrome P450 specialized for the metabolism of fatty acid hydroperoxides. Song WC, Funk CD, Brash AR (1993) Proc Natl Acad Sci U S A 90: 8519-23 Conserved nucleotide sequences in the open reading frame and 3' untranslated region of selenoprotein P mRNA. Hill KE, Lloyd RS, Burk RF (1993) Proc Natl Acad Sci U S A 90: 537-41 Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins. Barseguian K, Lutterbach B, Hiebert SW, Nickerson J, Lian JB, Stein JL, van Wijnen AJ, Stein GS (2002) Proc Natl Acad Sci U S A 99: 15434-9 Cell-permeable NM23 blocks the maintenance and progression of established pulmonary metastasis. Lim J, Jang G, Kang S, Lee G, Nga do TT, Phuong do TL, Kim H, El-Rifai W, Ruley HE, Jo D (2011) Cancer Res 71: 7216-25 Induction of lateral lumens through disruption of a monoleucine-based basolateral-sorting motif in betacellulin. Singh B, Bogatcheva G, Starchenko A, Sinnaeve J, Lapierre LA, Williams JA, Goldenring JR, Coffey RJ (2015) J Cell Sci 128: 3444-55 Differential requirement for tapasin in the presentation of leader- and insulin-derived peptide antigens to Qa-1b-restricted CTLs. Li L, Sullivan BA, Aldrich CJ, Soloski MJ, Forman J, Grandea AG, Jensen PE, Van Kaer L (2004) J Immunol 173: 3707-15 The transmembrane domain of the respiratory syncytial virus F protein is an orientation-independent apical plasma membrane sorting sequence. Brock SC, Heck JM, McGraw PA, Crowe JE (2005) J Virol 79: 12528-35 Discovery of an operon that participates in agmatine metabolism and regulates biofilm formation in Pseudomonas aeruginosa. Williams BJ, Du RH, Calcutt MW, Abdolrasulnia R, Christman BW, Blackwell TS (2010) Mol Microbiol 76: 104-19 A signal sequence is sufficient for green fluorescent protein to be routed to regulated secretory granules. El Meskini R, Jin L, Marx R, Bruzzaniti A, Lee J, Emeson R, Mains R (2001) Endocrinology 142: 864-73 Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction. Bansal S, Leu AN, Gonzalez FJ, Guengerich FP, Chowdhury AR, Anandatheerthavarada HK, Avadhani NG (2014) J Biol Chem 289: 9936-51 Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. Lin YZ, Yao SY, Veach RA, Torgerson TR, Hawiger J (1995) J Biol Chem 270: 14255-8 Efficient endocytosis of the cystic fibrosis transmembrane conductance regulator requires a tyrosine-based signal. Prince LS, Peter K, Hatton SR, Zaliauskiene L, Cotlin LF, Clancy JP, Marchase RB, Collawn JF (1999) J Biol Chem 274: 3602-9 Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase. Shiota C, Coffey J, Grimsby J, Grippo JF, Magnuson MA (1999) J Biol Chem 274: 37125-30 Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. Marchenko ND, Zaika A, Moll UM (2000) J Biol Chem 275: 16202-12 Intracellular localization of processing events in human surfactant protein B biosynthesis. Korimilli A, Gonzales LW, Guttentag SH (2000) J Biol Chem 275: 8672-9 Functional expression of bovine 17 alpha-hydroxylase in COS 1 cells is dependent upon the presence of an amino-terminal signal anchor sequence. Clark BJ, Waterman MR (1992) J Biol Chem 267: 24568-74 Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. Atherton JC, Cao P, Peek RM, Tummuru MK, Blaser MJ, Cover TL (1995) J Biol Chem 270: 17771-7 Sorting of yeast alpha 1,3 mannosyltransferase is mediated by a lumenal domain interaction, and a transmembrane domain signal that can confer clathrin-dependent Golgi localization to a secreted protein. Graham TR, Krasnov VA (1995) Mol Biol Cell 6: 809-24 Human liver mitochondrial cytochrome P450 2D6--individual variations and implications in drug metabolism. Sangar MC, Anandatheerthavarada HK, Tang W, Prabu SK, Martin MV, Dostalek M, Guengerich FP, Avadhani NG (2009) FEBS J 276: 3440-53 Growth phase-dependent composition of the Helicobacter pylori exoproteome. Snider CA, Voss BJ, McDonald WH, Cover TL (2016) J Proteomics 130: 94-107 Tailoring of membrane proteins by alternative splicing of pre-mRNA. Mittendorf KF, Deatherage CL, Ohi MD, Sanders CR (2012) Biochemistry 51: 5541-56 Expression in Escherichia coli of functional cytochrome P450c17 lacking its hydrophobic amino-terminal signal anchor. Sagara Y, Barnes HJ, Waterman MR (1993) Arch Biochem Biophys 304: 272-8 Direct expression of mature bovine adrenodoxin in Escherichia coli. Palin MF, Berthiaume L, Lehoux JG, Waterman MR, Sygusch J (1992) Arch Biochem Biophys 295: 126-31 Functional characterization of chimpanzee cytomegalovirus chemokine, vCXCL-1(CCMV). Miller-Kittrell M, Sai J, Penfold M, Richmond A, Sparer TE (2007) Virology 364: 454-65 Identification of genetic variants of human cytochrome P450 2D6 with impaired mitochondrial targeting. Sangar MC, Anandatheerthavarada HK, Martin MV, Guengerich FP, Avadhani NG (2010) Mol Genet Metab 99: 90-7 A type II ribonuclease H from Leishmania mitochondria: an enzyme essential for the growth of the parasite. Misra S, Bennett J, Friew YN, Abdulghani J, Irvin-Wilson CV, Tripathi MK, Williams S, Chaudhuri M, Chaudhuri G (2005) Mol Biochem Parasitol 143: 135-45 Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides. Gomez JA, Gama V, Yoshida T, Sun W, Hayes P, Leskov K, Boothman D, Matsuyama S (2007) Biochem Soc Trans 35: 797-801
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