Evolutionarily divergent electron donor proteins interact with P450MT2 through the same helical domain but different contact points. Anandatheerthavarada HK, Amuthan G, Biswas G, Robin MA, Murali R, Waterman MR, Avadhani NG (2001) EMBO J 20: 2394-403 Simultaneous transfection of COS-1 cells with mitochondrial and microsomal steroid hydroxylases: incorporation of a steroidogenic pathway into nonsteroidogenic cells. Zuber MX, Mason JI, Simpson ER, Waterman MR (1988) Proc Natl Acad Sci U S A 85: 699-703 Molecular cloning and amino acid sequence of the precursor form of bovine adrenodoxin: evidence for a previously unidentified COOH-terminal peptide. Okamura T, John ME, Zuber MX, Simpson ER, Waterman MR (1985) Proc Natl Acad Sci U S A 82: 5705-9 Transcriptional regulation of steroid hydroxylase genes by corticotropin. John ME, John MC, Boggaram V, Simpson ER, Waterman MR (1986) Proc Natl Acad Sci U S A 83: 4715-9 No mutation in cytochrome P450 side chain cleavage in a patient with congenital lipoid adrenal hyperplasia. Sakai Y, Yanase T, Okabe Y, Hara T, Waterman MR, Takayanagi R, Haji M, Nawata H (1994) J Clin Endocrinol Metab 79: 1198-201 Levels of messenger ribonucleic acid encoding cholesterol side-chain cleavage cytochrome P-450, 17 alpha-hydroxylase cytochrome P-450, adrenodoxin, and low density lipoprotein receptor in bovine follicles and corpora lutea throughout the ovarian cycle. Rodgers RJ, Waterman MR, Simpson ER (1987) Mol Endocrinol 1: 274-9 Cytochromes P-450scc, P-450(17)alpha, adrenodoxin, and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase in bovine follicles and corpora lutea. Changes in specific contents during the ovarian cycle. Rodgers RJ, Waterman MR, Simpson ER (1986) Endocrinology 118: 1366-74 Developmentally regulated expression of adrenal 17 alpha-hydroxylase cytochrome P450 in the mouse embryo. Keeney DS, Jenkins CM, Waterman MR (1995) Endocrinology 136: 4872-9 Identification by site-directed mutagenesis of two lysine residues in cholesterol side chain cleavage cytochrome P450 that are essential for adrenodoxin binding. Wada A, Waterman MR (1992) J Biol Chem 267: 22877-82 Regulation of rat adrenal messenger RNA and protein levels for cytochrome P-450s and adrenodoxin by dietary sodium depletion or potassium intake. Tremblay A, Waterman MR, Parker KL, Lehoux JG (1991) J Biol Chem 266: 2245-51 Evidence for the presence of cholesterol side chain cleavage cytochrome P-450 and adrenodoxin in fresh granulosa cells. Effects of follicle-stimulating hormone and cyclic AMP on cholesterol side chain cleavage cytochrome P-450 synthesis and activity. Funkenstein B, Waterman MR, Masters BS, Simpson ER (1983) J Biol Chem 258: 10187-91 Transcription of the bovine adrenodoxin gene produces two species of mRNA of which only one is translated into adrenodoxin. Kagimoto M, Kagimoto K, Simpson ER, Waterman MR (1988) J Biol Chem 263: 8925-8 Multiple species of bovine adrenodoxin mRNA. Occurrence of two different mitochondrial precursor sequences associated with the same mature sequence. Okamura T, Kagimoto M, Simpson ER, Waterman MR (1987) J Biol Chem 262: 10335-8 Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction. Bansal S, Leu AN, Gonzalez FJ, Guengerich FP, Chowdhury AR, Anandatheerthavarada HK, Avadhani NG (2014) J Biol Chem 289: 9936-51 Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs of cyclic AMP. Kramer RE, Rainey WE, Funkenstein B, Dee A, Simpson ER, Waterman MR (1984) J Biol Chem 259: 707-13 Induction of synthesis of cholesterol side chain cleavage cytochrome P-450 and adrenodoxin by follicle-stimulating hormone, 8-bromo-cyclic AMP, and low density lipoprotein in cultured bovine granulosa cells. Funkenstein B, Waterman MR, Simpson ER (1984) J Biol Chem 259: 8572-7 Discriminatory processing of the precursor forms of cytochrome P-450scc and adrenodoxin by adrenocortical and heart mitochondria. Matocha MF, Waterman MR (1984) J Biol Chem 259: 8672-8 Synthesis and processing of mitochondrial steroid hydroxylases. In vivo maturation of the precursor forms of cytochrome P-450scc, cytochrome P-450(11)beta, and adrenodoxin. Matocha MF, Waterman MR (1985) J Biol Chem 260: 12259-65 An additional electrostatic interaction between adrenodoxin and P450c27 (CYP27A1) results in tighter binding than between adrenodoxin and p450scc (CYP11A1). Pikuleva IA, Cao C, Waterman MR (1999) J Biol Chem 274: 2045-52 Adrenodoxin biosynthesis by bovine adrenal cells in monolayer culture. Induction by adrenocorticotropin. Kramer RE, Anderson CM, Peterson JA, Simpson ER, Waterman MR (1982) J Biol Chem 257: 14921-5 Levels of adrenodoxin, NADPH-cytochrome P-450 reductase and cytochromes P-45011 beta, P-45021, P-450scc, in adrenal zona fasciculata-reticularis tissue from androgen-treated rats. Brownie AC, Bhasker CR, Waterman MR (1988) Mol Cell Endocrinol 55: 15-20 cAMP-dependent and tissue-specific expression of genes encoding steroidogenic enzymes in bovine luteal and granulosa cells in primary culture. Lauber ME, Kagawa N, Waterman MR, Simpson ER (1993) Mol Cell Endocrinol 93: 227-33 Incorporation of steroidogenic pathways which produce cortisol and aldosterone from cholesterol into nonsteroidogenic cells. Mathew PA, Mason JI, Trant JM, Waterman MR (1990) Mol Cell Endocrinol 73: 73-80 Probing the interaction of bovine cytochrome P450scc (CYP11A1) with adrenodoxin: evaluating site-directed mutations by molecular modeling. Usanov SA, Graham SE, Lepesheva GI, Azeva TN, Strushkevich NV, Gilep AA, Estabrook RW, Peterson JA (2002) Biochemistry 41: 8310-20 Two promoters in the bovine adrenodoxin gene and the role of associated, unique cAMP-responsive sequences. Chen JY, Waterman MR (1992) Biochemistry 31: 2400-7 Three zinc finger nuclear proteins, Sp1, Sp3, and a ZBP-89 homologue, bind to the cyclic adenosine monophosphate-responsive sequence of the bovine adrenodoxin gene and regulate transcription. Cheng PY, Kagawa N, Takahashi Y, Waterman MR (2000) Biochemistry 39: 4347-57 The tertiary structure of full-length bovine adrenodoxin suggests functional dimers. Pikuleva IA, Tesh K, Waterman MR, Kim Y (2000) Arch Biochem Biophys 373: 44-55 Heterologous expression, purification, and properties of human cytochrome P450 27C1. Wu ZL, Bartleson CJ, Ham AJ, Guengerich FP (2006) Arch Biochem Biophys 445: 138-46 Direct expression of mature bovine adrenodoxin in Escherichia coli. Palin MF, Berthiaume L, Lehoux JG, Waterman MR, Sygusch J (1992) Arch Biochem Biophys 295: 126-31 Protein synthesis inhibitors and ethanol selectively enhance heterologous expression of P450s and related proteins in Escherichia coli. Kusano K, Waterman MR, Sakaguchi M, Omura T, Kagawa N (1999) Arch Biochem Biophys 367: 129-36 Turnover of newly synthesized cytochromes P-450scc and P-45011 beta and adrenodoxin in bovine adrenocortical cells in monolayer culture: effect of adrenocorticotropin. Boggaram V, Zuber MX, Waterman MR (1984) Arch Biochem Biophys 231: 518-23 Induction of synthesis of bovine adrenocortical cytochromes P-450scc, P-45011 beta, P-450C21, and adrenodoxin by prostaglandins E2 and F2 alpha and cholera toxin. Boggaram V, Simpson ER, Waterman MR (1984) Arch Biochem Biophys 231: 271-9 Cell-free synthesis of precursor forms of mitochondrial steroid hydroxylase enzymes of the bovine adrenal cortex. Kramer RE, Du Bois RN, Simpson ER, Anderson CM, Kashiwagi K, Lambeth JD, Jefcoate CR, Waterman MR (1982) Arch Biochem Biophys 215: 478-85 Preimplantation mouse blastocysts fail to express CYP genes required for estrogen biosynthesis. Strömstedt M, Keeney DS, Waterman MR, Paria BC, Conley AJ, Dey SK (1996) Mol Reprod Dev 43: 428-36 Induction of synthesis of steroidogenic enzymes by corticotropin in bovine adrenocortical cells in culture. Simpson ER, Waterman MR (1983) Biochem Soc Trans 11: 653-5 Effect of ACTH on the stability of mRNAs encoding bovine adrenocortical P-450scc, P-45011 beta, P-45017 alpha, P-450C21 and adrenodoxin. Boggaram V, John ME, Simpson ER, Waterman MR (1989) Biochem Biophys Res Commun 160: 1227-32 Studies on rhodanese synthesis in bovine adrenocortical cells. Boggaram V, Horowitz P, Waterman MR (1985) Biochem Biophys Res Commun 130: 407-11 ACTH-mediated induction of synthesis and activity of cytochrome P-450s and related enzymes in cultured bovine adrenocortical cells. Waterman MR (1982) Xenobiotica 12: 773-86 A tricistronic human adrenodoxin reductase-adrenodoxin-cytochrome P450 27A1 vector system for substrate hydroxylation in Escherichia coli. Salamanca-Pinzón SG, Guengerich FP (2011) Protein Expr Purif 79: 231-6 Role of positively charged residues lys267, lys270, and arg411 of cytochrome p450scc (CYP11A1) in interaction with adrenodoxin. Strushkevich NV, Azeva TN, Lepesheva GI, Usanov SA (2005) Biochemistry (Mosc) 70: 664-71
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