Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Yan F, Cao H, Cover TL, Whitehead R, Washington MK, Polk DB (2007) Gastroenterology 132: 562-75 Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism. Yan F, Cao H, Cover TL, Washington MK, Shi Y, Liu L, Chaturvedi R, Peek RM, Wilson KT, Polk DB (2011) J Clin Invest 121: 2242-53 Nasopharyngeal Lactobacillus is associated with a reduced risk of childhood wheezing illnesses following acute respiratory syncytial virus infection in infancy. Rosas-Salazar C, Shilts MH, Tovchigrechko A, Schobel S, Chappell JD, Larkin EK, Gebretsadik T, Halpin RA, Nelson KE, Moore ML, Anderson LJ, Peebles RS, Das SR, Hartert TV (2018) J Allergy Clin Immunol 142: 1447-1456.e9 Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis. Lertpiriyapong K, Whary MT, Muthupalani S, Lofgren JL, Gamazon ER, Feng Y, Ge Z, Wang TC, Fox JG (2014) Gut 63: 54-63 Cellular folate binding proteins; function and significance. Wagner C (1982) Annu Rev Nutr 2: 229-48 An LGG-derived protein promotes IgA production through upregulation of APRIL expression in intestinal epithelial cells. Wang Y, Liu L, Moore DJ, Shen X, Peek RM, Acra SA, Li H, Ren X, Polk DB, Yan F (2017) Mucosal Immunol 10: 373-384 Supplementation of p40, a Lactobacillus rhamnosus GG-derived protein, in early life promotes epidermal growth factor receptor-dependent intestinal development and long-term health outcomes. Shen X, Liu L, Peek RM, Acra SA, Moore DJ, Wilson KT, He F, Polk DB, Yan F (2018) Mucosal Immunol 11: 1316-1328 Neonatal colonization of mice with LGG promotes intestinal development and decreases susceptibility to colitis in adulthood. Yan F, Liu L, Cao H, Moore DJ, Washington MK, Wang B, Peek RM, Acra SA, Polk DB (2017) Mucosal Immunol 10: 117-127 Activation of epidermal growth factor receptor mediates mucin production stimulated by p40, a Lactobacillus rhamnosus GG-derived protein. Wang L, Cao H, Liu L, Wang B, Walker WA, Acra SA, Yan F (2014) J Biol Chem 289: 20234-44 Probiotic bacterium prevents cytokine-induced apoptosis in intestinal epithelial cells. Yan F, Polk DB (2002) J Biol Chem 277: 50959-65 A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor. Yan F, Liu L, Dempsey PJ, Tsai YH, Raines EW, Wilson CL, Cao H, Cao Z, Liu L, Polk DB (2013) J Biol Chem 288: 30742-30751 Probiotics as functional food in the treatment of diarrhea. Yan F, Polk DB (2006) Curr Opin Clin Nutr Metab Care 9: 717-21 Probiotics and immune health. Yan F, Polk DB (2011) Curr Opin Gastroenterol 27: 496-501 Addition of deoxyribose to guanine and modified DNA based by Lactobacillus helveticus trans-N-deoxyribosylase. Müller M, Hutchinson LK, Guengerich FP (1996) Chem Res Toxicol 9: 1140-4 Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism. Seth A, Yan F, Polk DB, Rao RK (2008) Am J Physiol Gastrointest Liver Physiol 294: G1060-9 New scientific paradigms for probiotics and prebiotics. Reid G, Sanders ME, Gaskins HR, Gibson GR, Mercenier A, Rastall R, Roberfroid M, Rowland I, Cherbut C, Klaenhammer TR (2003) J Clin Gastroenterol 37: 105-18 Species-specific identification of commercial probiotic strains. Yeung PS, Sanders ME, Kitts CL, Cano R, Tong PS (2002) J Dairy Sci 85: 1039-51 High molecular weight complexes of folic acid in mammalian tissues. Zamierowski M, Wagner C (1974) Biochem Biophys Res Commun 60: 81-7 Functional analysis of the p40 and p75 proteins from Lactobacillus casei BL23. Bäuerl C, Pérez-Martínez G, Yan F, Polk DB, Monedero V (2010) J Mol Microbiol Biotechnol 19: 231-41
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