Each of the activities of signal recognition particle (SRP) is contained within a distinct domain: analysis of biochemical mutants of SRP. Siegel V, Walter P (1988) Cell 52: 39-49 Recognition of a transmembrane domain: another role for the ribosome? Siegel V (1997) Cell 90: 5-8 ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Ye J, Rawson RB, Komuro R, Chen X, Davé UP, Prywes R, Brown MS, Goldstein JL (2000) Mol Cell 6: 1355-64 Flippases and vesicle-mediated protein transport. Graham TR (2004) Trends Cell Biol 14: 670-7 Coordination of Golgi functions by phosphatidylinositol 4-kinases. Graham TR, Burd CG (2011) Trends Cell Biol 21: 113-21 Assembly of proteins in the endoplasmic reticulum. Siegel V, Walter P (1989) Curr Opin Cell Biol 1: 635-8 ER membrane-bending proteins are necessary for de novo nuclear pore formation. Dawson TR, Lazarus MD, Hetzer MW, Wente SR (2009) J Cell Biol 184: 659-75 Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles. Ktistakis NT, Brown HA, Waters MG, Sternweis PC, Roth MG (1996) J Cell Biol 134: 295-306 Clathrin-dependent localization of alpha 1,3 mannosyltransferase to the Golgi complex of Saccharomyces cerevisiae. Graham TR, Seeger M, Payne GS, MacKay VL, Emr SD (1994) J Cell Biol 127: 667-78 Elongation arrest is not a prerequisite for secretory protein translocation across the microsomal membrane. Siegel V, Walter P (1985) J Cell Biol 100: 1913-21 Role for Drs2p, a P-type ATPase and potential aminophospholipid translocase, in yeast late Golgi function. Chen CY, Ingram MF, Rosal PH, Graham TR (1999) J Cell Biol 147: 1223-36 Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A. Ktistakis NT, Brown HA, Sternweis PC, Roth MG (1995) Proc Natl Acad Sci U S A 92: 4952-6 Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins. Brooks C, Wei Q, Feng L, Dong G, Tao Y, Mei L, Xie ZJ, Dong Z (2007) Proc Natl Acad Sci U S A 104: 11649-54 Drs2p-coupled aminophospholipid translocase activity in yeast Golgi membranes and relationship to in vivo function. Natarajan P, Wang J, Hua Z, Graham TR (2004) Proc Natl Acad Sci U S A 101: 10614-9 Noninvasive intracellular delivery of functional peptides and proteins. Hawiger J (1999) Curr Opin Chem Biol 3: 89-94 Apoptotic response of HL-60 human leukemia cells to the antitumor drug TAS-103. Kluza J, Lansiaux A, Wattez N, Mahieu C, Osheroff N, Bailly C (2000) Cancer Res 60: 4077-84 Darpp-32: a novel antiapoptotic gene in upper gastrointestinal carcinomas. Belkhiri A, Zaika A, Pidkovka N, Knuutila S, Moskaluk C, El-Rifai W (2005) Cancer Res 65: 6583-92 Calpains play a role in insulin secretion and action. Sreenan SK, Zhou YP, Otani K, Hansen PA, Currie KP, Pan CY, Lee JP, Ostrega DM, Pugh W, Horikawa Y, Cox NJ, Hanis CL, Burant CF, Fox AP, Bell GI, Polonsky KS (2001) Diabetes 50: 2013-20 Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter. Barker EL, Moore KR, Rakhshan F, Blakely RD (1999) J Neurosci 19: 4705-17 Pleiotropic regulation of vascular smooth muscle tone by cyclic GMP-dependent protein kinase. Lincoln TM, Komalavilas P, Cornwell TL (1994) Hypertension 23: 1141-7 Effects of intracellular free cholesterol accumulation on macrophage viability: a model for foam cell death. Kellner-Weibel G, Jerome WG, Small DM, Warner GJ, Stoltenborg JK, Kearney MA, Corjay MH, Phillips MC, Rothblat GH (1998) Arterioscler Thromb Vasc Biol 18: 423-31 Sugar-free frosting, a homolog of SAD kinase, drives neural-specific glycan expression in the Drosophila embryo. Baas S, Sharrow M, Kotu V, Middleton M, Nguyen K, Flanagan-Steet H, Aoki K, Tiemeyer M (2011) Development 138: 553-63 Reovirus forms neo-organelles for progeny particle assembly within reorganized cell membranes. Fernández de Castro I, Zamora PF, Ooms L, Fernández JJ, Lai CM, Mainou BA, Dermody TS, Risco C (2014) MBio 5: Coupled glucose transport and metabolism in cultured neuronal cells: determination of the rate-limiting step. Whitesell RR, Ward M, McCall AL, Granner DK, May JM (1995) J Cereb Blood Flow Metab 15: 814-26 Murine hepatitis virus nonstructural protein 4 regulates virus-induced membrane modifications and replication complex function. Gadlage MJ, Sparks JS, Beachboard DC, Cox RG, Doyle JD, Stobart CC, Denison MR (2010) J Virol 84: 280-90 Mouse hepatitis virus replicase proteins associate with two distinct populations of intracellular membranes. Sims AC, Ostermann J, Denison MR (2000) J Virol 74: 5647-54 Reovirus apoptosis and virulence are regulated by host cell membrane penetration efficiency. Danthi P, Kobayashi T, Holm GH, Hansberger MW, Abel TW, Dermody TS (2008) J Virol 82: 161-72 Intracellular topography of rhodopsin regeneration in vertebrate rods. Williams TP, Penn JS (1985) J Gen Physiol 86: 413-22 Hepatic expression of ErbB3 is repressed by insulin in a pathway sensitive to PI-3 kinase inhibitors. Carver RS, Mathew PM, Russell WE (1997) Endocrinology 138: 5195-201 Monoclonal antibodies for structure-function studies of (R)-3-hydroxybutyrate dehydrogenase, a lipid-dependent membrane-bound enzyme. Adami P, Duncan TM, McIntyre JO, Carter CE, Fu C, Melin M, Latruffe N, Fleischer S (1993) Biochem J 292 ( Pt 3): 863-72 Oxygenation of biological membranes by the pure reticulocyte lipoxygenase. Kuhn H, Belkner J, Wiesner R, Brash AR (1990) J Biol Chem 265: 18351-61 Endotoxin priming of neutrophils requires endocytosis and NADPH oxidase-dependent endosomal reactive oxygen species. Lamb FS, Hook JS, Hilkin BM, Huber JN, Volk AP, Moreland JG (2012) J Biol Chem 287: 12395-404 Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer. Stoeltzing O, Liu W, Reinmuth N, Fan F, Parikh AA, Bucana CD, Evans DB, Semenza GL, Ellis LM (2003) Am J Pathol 163: 1001-11 Defect in glucokinase translocation in Zucker diabetic fatty rats. Fujimoto Y, Donahue EP, Shiota M (2004) Am J Physiol Endocrinol Metab 287: E414-23 Subcellular organelle lipidomics in TLR-4-activated macrophages. Andreyev AY, Fahy E, Guan Z, Kelly S, Li X, McDonald JG, Milne S, Myers D, Park H, Ryan A, Thompson BM, Wang E, Zhao Y, Brown HA, Merrill AH, Raetz CR, Russell DW, Subramaniam S, Dennis EA (2010) J Lipid Res 51: 2785-97 Metabotropic glutamate receptor (mGluR)-mediated potentiation of cyclic AMP responses does not require phosphoinositide hydrolysis: mediation by a group II-like mGluR. Winder DG, Conn PJ (1995) J Neurochem 64: 592-9 Opioid signal transduction in intact and fragmented SH-SY5Y neural cells. Carter BD, Medzihradsky F (1992) J Neurochem 58: 1611-9 Reversed activity of mitochondrial adenine nucleotide translocator in ischemia-reperfusion. Belous A, Knox C, Nicoud IB, Pierce J, Anderson C, Pinson CW, Chari RS (2003) Transplantation 75: 1717-23 Diarrhea-associated HIV-1 APIs potentiate muscarinic activation of Cl- secretion by T84 cells via prolongation of cytosolic Ca2+ signaling. Rufo PA, Lin PW, Andrade A, Jiang L, Rameh L, Flexner C, Alper SL, Lencer WI (2004) Am J Physiol Cell Physiol 286: C998-C1008 Measuring translocation of fluorescent lipid derivatives across yeast Golgi membranes. Natarajan P, Graham TR (2006) Methods 39: 163-8
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.