-
Communities
-
Explore Vanderbilt communities
By latest
Featured community
Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
-
- Resources
-
People
-
Publications
-
Explore publications
-
Keyword Connections
Connections to Cholesterol, LDL are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Cholesterol, LDL.
Members
- No matching connections
Resources
- No matching connections
Communities
- No matching connections
Publications
- Inactivating mutations in NPC1L1 and protection from coronary heart disease.
Myocardial Infarction Genetics Consortium Investigators, Stitziel NO, Won HH, Morrison AC, Peloso GM, Do R, Lange LA, Fontanillas P, Gupta N, Duga S, Goel A, Farrall M, Saleheen D, Ferrario P, König I, Asselta R, Merlini PA, Marziliano N, Notarangelo MF, Schick U, Auer P, Assimes TL, Reilly M, Wilensky R, Rader DJ, Hovingh GK, Meitinger T, Kessler T, Kastrati A, Laugwitz KL, Siscovick D, Rotter JI, Hazen SL, Tracy R, Cresci S, Spertus J, Jackson R, Schwartz SM, Natarajan P, Crosby J, Muzny D, Ballantyne C, Rich SS, O'Donnell CJ, Abecasis G, Sunaev S, Nickerson DA, Buring JE, Ridker PM, Chasman DI, Austin E, Kullo IJ, Weeke PE, Shaffer CM, Bastarache LA, Denny JC, Roden DM, Palmer C, Deloukas P, Lin DY, Tang ZZ, Erdmann J, Schunkert H, Danesh J, Marrugat J, Elosua R, Ardissino D, McPherson R, Watkins H, Reiner AP, Wilson JG, Altshuler D, Gibbs RA, Lander ES, Boerwinkle E, Gabriel S, Kathiresan S
(2014) N Engl J Med 371: 2072-82 - Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.
Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ, JUPITER Study Group
(2008) N Engl J Med 359: 2195-207 - Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community.
Dhingra R, Sullivan L, Jacques PF, Wang TJ, Fox CS, Meigs JB, D'Agostino RB, Gaziano JM, Vasan RS
(2007) Circulation 116: 480-8 - Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.
Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K, Arsenault BJ, Donnelly LA, Wiggins KL, Avery CL, Griffin P, Feng Q, Taylor KD, Li G, Evans DS, Smith AV, de Keyser CE, Johnson AD, de Craen AJ, Stott DJ, Buckley BM, Ford I, Westendorp RG, Slagboom PE, Sattar N, Munroe PB, Sever P, Poulter N, Stanton A, Shields DC, O'Brien E, Shaw-Hawkins S, Chen YD, Nickerson DA, Smith JD, Dubé MP, Boekholdt SM, Hovingh GK, Kastelein JJ, McKeigue PM, Betteridge J, Neil A, Durrington PN, Doney A, Carr F, Morris A, McCarthy MI, Groop L, Ahlqvist E, Welcome Trust Case Control Consortium, Bis JC, Rice K, Smith NL, Lumley T, Whitsel EA, Stürmer T, Boerwinkle E, Ngwa JS, O'Donnell CJ, Vasan RS, Wei WQ, Wilke RA, Liu CT, Sun F, Guo X, Heckbert SR, Post W, Sotoodehnia N, Arnold AM, Stafford JM, Ding J, Herrington DM, Kritchevsky SB, Eiriksdottir G, Launer LJ, Harris TB, Chu AY, Giulianini F, MacFadyen JG, Barratt BJ, Nyberg F, Stricker BH, Uitterlinden AG, Hofman A, Rivadeneira F, Emilsson V, Franco OH, Ridker PM, Gudnason V, Liu Y, Denny JC, Ballantyne CM, Rotter JI, Adrienne Cupples L, Psaty BM, Palmer CN, Tardif JC, Colhoun HM, Hitman G, Krauss RM, Wouter Jukema J, Caulfield MJ
(2014) Nat Commun 5: 5068 - A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers.
Mosley JD, Feng Q, Wells QS, Van Driest SL, Shaffer CM, Edwards TL, Bastarache L, Wei WQ, Davis LK, McCarty CA, Thompson W, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Verma SS, Karnes JH, Weiss ST, Wang TJ, Stein CM, Denny JC, Roden DM
(2018) Nat Commun 9: 3522 - Hemoglobin a1c and the progression of coronary artery calcification among adults without diabetes.
Carson AP, Steffes MW, Carr JJ, Kim Y, Gross MD, Carnethon MR, Reis JP, Loria CM, Jacobs DR, Lewis CE
(2015) Diabetes Care 38: 66-71 - Factors associated with paraoxonase genotypes and activity in a diverse, young, healthy population: the Coronary Artery Risk Development in Young Adults (CARDIA) study.
Thyagarajan B, Jacobs DR, Carr JJ, Alozie O, Steffes MW, Kailash P, Hayes JH, Gross MD
(2008) Clin Chem 54: 738-46 - Characterization of statin dose response in electronic medical records.
Wei WQ, Feng Q, Jiang L, Waitara MS, Iwuchukwu OF, Roden DM, Jiang M, Xu H, Krauss RM, Rotter JI, Nickerson DA, Davis RL, Berg RL, Peissig PL, McCarty CA, Wilke RA, Denny JC
(2014) Clin Pharmacol Ther 95: 331-8 - Individual carotenoid concentrations in adipose tissue and plasma as biomarkers of dietary intake.
El-Sohemy A, Baylin A, Kabagambe E, Ascherio A, Spiegelman D, Campos H
(2002) Am J Clin Nutr 76: 172-9 - Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice.
Babaev VR, Yancey PG, Ryzhov SV, Kon V, Breyer MD, Magnuson MA, Fazio S, Linton MF
(2005) Arterioscler Thromb Vasc Biol 25: 1647-53 - ACAT1 deficiency disrupts cholesterol efflux and alters cellular morphology in macrophages.
Dove DE, Su YR, Zhang W, Jerome WG, Swift LL, Linton MF, Fazio S
(2005) Arterioscler Thromb Vasc Biol 25: 128-34 - Cyclooxygenase-2-dependent prostacyclin formation is regulated by low density lipoprotein cholesterol in vitro.
Smith LH, Boutaud O, Breyer M, Morrow JD, Oates JA, Vaughan DE
(2002) Arterioscler Thromb Vasc Biol 22: 983-8 - Human PCSK9 promotes hepatic lipogenesis and atherosclerosis development via apoE- and LDLR-mediated mechanisms.
Tavori H, Giunzioni I, Predazzi IM, Plubell D, Shivinsky A, Miles J, Devay RM, Liang H, Rashid S, Linton MF, Fazio S
(2016) Cardiovasc Res 110: 268-78 - Lovastatin in the treatment of multifactorial hyperlipidemia associated with proteinuria.
Golper TA, Illingworth DR, Morris CD, Bennett WM
(1989) Am J Kidney Dis 13: 312-20 - Long-term efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in hyperlipidaemic patients with diabetes or metabolic syndrome.
Fazio S, Guyton JR, Lin J, Tomassini JE, Shah A, Tershakovec AM
(2010) Diabetes Obes Metab 12: 983-93 - The effect of genetic variation in PCSK9 on the LDL-cholesterol response to statin therapy.
Feng Q, Wei WQ, Chung CP, Levinson RT, Bastarache L, Denny JC, Stein CM
(2017) Pharmacogenomics J 17: 204-208 - High-density lipoprotein (HDL) cholesterol: leveraging practice-based biobank cohorts to characterize clinical and genetic predictors of treatment outcome.
Wilke RA
(2011) Pharmacogenomics J 11: 162-73 - No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population.
Dumitrescu L, Carty CL, Franceschini N, Hindorff LA, Cole SA, Bůžková P, Schumacher FR, Eaton CB, Goodloe RJ, Duggan DJ, Haessler J, Cochran B, Henderson BE, Cheng I, Johnson KC, Carlson CS, Love SA, Brown-Gentry K, Nato AQ, Quibrera M, Shohet RV, Ambite JL, Wilkens LR, Le Marchand L, Haiman CA, Buyske S, Kooperberg C, North KE, Fornage M, Crawford DC
(2013) Hum Genet 132: 1427-31 - Serum vitamins A and E as modifiers of lipid trait genetics in the National Health and Nutrition Examination Surveys as part of the Population Architecture using Genomics and Epidemiology (PAGE) study.
Dumitrescu L, Goodloe R, Brown-Gentry K, Mayo P, Allen M, Jin H, Gillani NB, Schnetz-Boutaud N, Dilks HH, Crawford DC
(2012) Hum Genet 131: 1699-708 - Atazanavir improves cardiometabolic measures but not vascular function in patients with long-standing type 1 diabetes mellitus.
Milian J, Goldfine AB, Zuflacht JP, Parmer C, Beckman JA
(2015) Acta Diabetol 52: 709-15 - Lysosomal sequestration of free and esterified cholesterol from oxidized low density lipoprotein in macrophages of different species.
Yancey PG, Jerome WG
(1998) J Lipid Res 39: 1349-61 - In vitro oxidation of low-density lipoprotein in two species of nonhuman primates subjected to caloric restriction.
Cefalu WT, Terry JG, Thomas MJ, Morgan TM, Edwards IJ, Rudel LL, Kemnitz JW, Weindruch R
(2000) J Gerontol A Biol Sci Med Sci 55: B355-61 - Occupation is more important than rural or urban residence in explaining the prevalence of metabolic and cardiovascular disease risk in Guatemalan adults.
Gregory CO, Dai J, Ramirez-Zea M, Stein AD
(2007) J Nutr 137: 1314-9 - Poly-omic prediction of complex traits: OmicKriging.
Wheeler HE, Aquino-Michaels K, Gamazon ER, Trubetskoy VV, Dolan ME, Huang RS, Cox NJ, Im HK
(2014) Genet Epidemiol 38: 402-15 - Nonpharmacologic treatment of dyslipidemia.
Houston MC, Fazio S, Chilton FH, Wise DE, Jones KB, Barringer TA, Bramlet DA
(2009) Prog Cardiovasc Dis 52: 61-94 - Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study.
Affuso F, Ruvolo A, Micillo F, Saccà L, Fazio S
(2010) Nutr Metab Cardiovasc Dis 20: 656-61 - Higher pericardial adiposity is associated with prevalent diabetes: The Coronary Artery Risk Development in Young Adults study.
Alman AC, Jacobs DR, Lewis CE, Snell-Bergeon JK, Carnethon MR, Terry JG, Goff DC, Ding J, Carr JJ
(2016) Nutr Metab Cardiovasc Dis 26: 326-32 - Caloric restriction lowers plasma lipoprotein (a) in male but not female rhesus monkeys.
Edwards IJ, Rudel LL, Terry JG, Kemnitz JW, Weindruch R, Zaccaro DJ, Cefalu WT
(2001) Exp Gerontol 36: 1413-8 - Ezetimibe in renal transplant patients with hyperlipidemia resistant to HMG-CoA reductase inhibitors.
Langone AJ, Chuang P
(2006) Transplantation 81: 804-7 - A double blind, placebo-controlled, randomized crossover study of the acute metabolic effects of olanzapine in healthy volunteers.
Albaugh VL, Singareddy R, Mauger D, Lynch CJ
(2011) PLoS One 6: e22662 - Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study.
Buyske S, Wu Y, Carty CL, Cheng I, Assimes TL, Dumitrescu L, Hindorff LA, Mitchell S, Ambite JL, Boerwinkle E, Buzkova P, Carlson CS, Cochran B, Duggan D, Eaton CB, Fesinmeyer MD, Franceschini N, Haessler J, Jenny N, Kang HM, Kooperberg C, Lin Y, Le Marchand L, Matise TC, Robinson JG, Rodriguez C, Schumacher FR, Voight BF, Young A, Manolio TA, Mohlke KL, Haiman CA, Peters U, Crawford DC, North KE
(2012) PLoS One 7: e35651 - Mixed modeling of meta-analysis P-values (MixMAP) suggests multiple novel gene loci for low density lipoprotein cholesterol.
Foulkes AS, Matthews GJ, Das U, Ferguson JF, Lin R, Reilly MP
(2013) PLoS One 8: e54812 - Cardiovascular Disease Risk Factors in Ghana during the Rural-to-Urban Transition: A Cross-Sectional Study.
Kodaman N, Aldrich MC, Sobota R, Asselbergs FW, Poku KA, Brown NJ, Moore JH, Williams SM
(2016) PLoS One 11: e0162753 - Health disparities among adult patients with a phenotypic diagnosis of familial hypercholesterolemia in the CASCADE-FH™ patient registry.
Amrock SM, Duell PB, Knickelbine T, Martin SS, O'Brien EC, Watson KE, Mitri J, Kindt I, Shrader P, Baum SJ, Hemphill LC, Ahmed CD, Andersen RL, Kullo IJ, McCann D, Larry JA, Murray MF, Fishberg R, Guyton JR, Wilemon K, Roe MT, Rader DJ, Ballantyne CM, Underberg JA, Thompson P, Duffy D, Linton MF, Shapiro MD, Moriarty PM, Knowles JW, Ahmad ZS
(2017) Atherosclerosis 267: 19-26 - Cholesterol-fed heterozygous Watanabe heritable hyperlipidemic rabbits: a new model for atherosclerosis.
Atkinson JB, Hoover RL, Berry KK, Swift LL
(1989) Atherosclerosis 78: 123-36 - Plasma insulin levels predict atherosclerotic lesion burden in obese hyperlipidemic mice.
Gruen ML, Saraswathi V, Nuotio-Antar AM, Plummer MR, Coenen KR, Hasty AH
(2006) Atherosclerosis 186: 54-64 - Rare PPARA variants and extreme response to fenofibrate in the Genetics of Lipid-Lowering Drugs and Diet Network Study.
Irvin MR, Zhang Q, Kabagambe EK, Perry RT, Straka RJ, Tiwari HK, Borecki IB, Shimmin LC, Stuart C, Zhong Y, Hixson JE, Arnett DK
(2012) Pharmacogenet Genomics 22: 367-72 - Using Human 'Experiments of Nature' to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors.
Jerome RN, Pulley JM, Roden DM, Shirey-Rice JK, Bastarache LA, R Bernard G, B Ekstrom L, Lancaster WJ, Denny JC
(2018) Drug Saf 41: 303-311 - Hormone replacement therapy is associated with increased C-reactive protein in women with Type 2 diabetes in the Diabetes Heart Study.
Bowden DW, Lohman K, Hsu FC, Langefeld CD, Carr JJ, Lenchik L, Wagenknecht LE, Freedman BI, Herrington DM
(2006) Diabet Med 23: 763-7 - A practical approach to risk assessment to prevent coronary artery disease and its complications.
Linton MF, Fazio S, National Cholesterol Education Program (NCEP)- the third Adult Treatment Panel (ATP III)
(2003) Am J Cardiol 92: 19i-26i
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.
