T cells from patients with Parkinson's disease recognize α-synuclein peptides. Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, Dillon MB, Carpenter C, Weiskopf D, Phillips E, Mallal S, Peters B, Frazier A, Lindestam Arlehamn CS, Sette A (2017) Nature 546: 656-661 The calculus of integrating differentiation: timing control of T-bet. Boothby M (2009) Immunity 30: 666-8 Central nervous system (CNS)-resident natural killer cells suppress Th17 responses and CNS autoimmune pathology. Hao J, Liu R, Piao W, Zhou Q, Vollmer TL, Campagnolo DI, Xiang R, La Cava A, Van Kaer L, Shi FD (2010) J Exp Med 207: 1907-21 Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation. Das J, Ren G, Zhang L, Roberts AI, Zhao X, Bothwell AL, Van Kaer L, Shi Y, Das G (2009) J Exp Med 206: 2407-16 Dynamic alterations in the conformation of the Ifng gene region during T helper cell differentiation. Eivazova ER, Aune TM (2004) Proc Natl Acad Sci U S A 101: 251-6 Hypoxia-inducible factors in CD4 T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity. Cho SH, Raybuck AL, Blagih J, Kemboi E, Haase VH, Jones RG, Boothby MR (2019) Proc Natl Acad Sci U S A 116: 8975-8984 Gamma delta T cell help of B cells is induced by repeated parasitic infection, in the absence of other T cells. Pao W, Wen L, Smith AL, Gulbranson-Judge A, Zheng B, Kelsoe G, MacLennan IC, Owen MJ, Hayday AC (1996) Curr Biol 6: 1317-25 Th1 and Th17 cells induce proliferative glomerulonephritis. Summers SA, Steinmetz OM, Li M, Kausman JY, Semple T, Edgtton KL, Borza DB, Braley H, Holdsworth SR, Kitching AR (2009) J Am Soc Nephrol 20: 2518-24 Human T-lymphotropic virus: exposure and prognosis. Soskolne CL, Heyland D, Phillips E (1986) CMAJ 134: 575-7 CD4+ lymphocyte cell enumeration for prediction of clinical course of human immunodeficiency virus disease: a review. Stein DS, Korvick JA, Vermund SH (1992) J Infect Dis 165: 352-63 Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells. Yi Y, McNerney M, Datta SK (2000) J Immunol 165: 6627-34 A murine locus on chromosome 18 controls NKT cell homeostasis and Th cell differentiation. Zhang F, Liang Z, Matsuki N, Van Kaer L, Joyce S, Wakeland EK, Aune TM (2003) J Immunol 171: 4613-20 Defective Th function induced by a dominant-negative cAMP response element binding protein mutation is reversed by Bcl-2. Zhang F, Rincon M, Flavell RA, Aune TM (2000) J Immunol 165: 1762-70 Proteasomes, TAP, and endoplasmic reticulum-associated aminopeptidase associated with antigen processing control CD4+ Th cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigens. Dragovic SM, Hill T, Christianson GJ, Kim S, Elliott T, Scott D, Roopenian DC, Van Kaer L, Joyce S (2011) J Immunol 186: 6683-92 Reversal of global CD4+ subset dysfunction is associated with spontaneous clinical resolution of pulmonary sarcoidosis. Oswald-Richter KA, Richmond BW, Braun NA, Isom J, Abraham S, Taylor TR, Drake JM, Culver DA, Wilkes DS, Drake WP (2013) J Immunol 190: 5446-53 Immunoregulation by T cells. I. Characterization of the IEk-specific Lbd self-reactive T cell clone that helps, suppresses and contrasupresses B cell responses. Quintáns J, Suzuki H, Sosman JA, Shah PD (1986) J Immunol 136: 1974-81 Modulation of CD4 Th cell differentiation by ganglioside GD1a in vitro. Shen W, Falahati R, Stark R, Leitenberg D, Ladisch S (2005) J Immunol 175: 4927-34 Regulation of the activity of IFN-gamma promoter elements during Th cell differentiation. Zhang F, Wang DZ, Boothby M, Penix L, Flavell RA, Aune TM (1998) J Immunol 161: 6105-12 Opposing roles for RelB and Bcl-3 in regulation of T-box expressed in T cells, GATA-3, and Th effector differentiation. Corn RA, Hunter C, Liou HC, Siebenlist U, Boothby MR (2005) J Immunol 175: 2102-10 B cell-intrinsic and -extrinsic regulation of antibody responses by PARP14, an intracellular (ADP-ribosyl)transferase. Cho SH, Raybuck A, Wei M, Erickson J, Nam KT, Cox RG, Trochtenberg A, Thomas JW, Williams J, Boothby M (2013) J Immunol 191: 3169-78 TCR and IL-12 receptor signals cooperate to activate an individual response element in the IFN-gamma promoter in effector Th cells. Zhang F, Nakamura T, Aune TM (1999) J Immunol 163: 728-35 Sculpting MHC class II-restricted self and non-self peptidome by the class I Ag-processing machinery and its impact on Th-cell responses. Spencer CT, Dragovic SM, Conant SB, Gray JJ, Zheng M, Samir P, Niu X, Moutaftsi M, Van Kaer L, Sette A, Link AJ, Joyce S (2013) Eur J Immunol 43: 1162-72 Selective matrix attachment regions in T helper cell subsets support loop conformation in the Ifng gene. Eivazova ER, Vassetzky YS, Aune TM (2007) Genes Immun 8: 35-43 Transcriptional reprogramming during T helper cell differentiation. Aune TM (2001) Immunol Res 23: 193-204 CD40-ligand in primate cardiac allograft and viral immunity. Pierson RN, Crowe JE, Pfeiffer S, Atkinson J, Azimzadeh A, Miller GG (2001) Immunol Res 23: 253-62 Targeting CD4(+) T cells for the treatment of sarcoidosis: a promising strategy? Celada LJ, Drake WP (2015) Immunotherapy 7: 57-66 Differential immune response to carbohydrate epitopes on allo- and xenografts: implications for accommodation. Tanemura M, Yin D, Chong A, Galili U (2000) Transplant Proc 32: 991-3
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.