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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Cricetinae are shown below. Double-click or tap a node for more information.
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Publications
- Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins.
Rameh LE, Chen CS, Cantley LC
(1995) Cell 83: 821-30 - Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA.
Smider V, Rathmell WK, Lieber MR, Chu G
(1994) Science 266: 288-91 - cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation.
Bhave G, Zhu W, Wang H, Brasier DJ, Oxford GS, Gereau RW
(2002) Neuron 35: 721-31 - Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitro.
Watanabe H, Yang T, Stroud DM, Lowe JS, Harris L, Atack TC, Wang DW, Hipkens SB, Leake B, Hall L, Kupershmidt S, Chopra N, Magnuson MA, Tanabe N, Knollmann BC, George AL, Roden DM
(2011) Circulation 124: 1001-11 - Screening for acute IKr block is insufficient to detect torsades de pointes liability: role of late sodium current.
Yang T, Chun YW, Stroud DM, Mosley JD, Knollmann BC, Hong C, Roden DM
(2014) Circulation 130: 224-34 - Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes.
Yang P, Kanki H, Drolet B, Yang T, Wei J, Viswanathan PC, Hohnloser SH, Shimizu W, Schwartz PJ, Stanton M, Murray KT, Norris K, George AL, Roden DM
(2002) Circulation 105: 1943-8 - Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.
Kumari M, Schoiswohl G, Chitraju C, Paar M, Cornaciu I, Rangrez AY, Wongsiriroj N, Nagy HM, Ivanova PT, Scott SA, Knittelfelder O, Rechberger GN, Birner-Gruenberger R, Eder S, Brown HA, Haemmerle G, Oberer M, Lass A, Kershaw EE, Zimmermann R, Zechner R
(2012) Cell Metab 15: 691-702 - Comparative sequence and x-inactivation analyses of a domain of escape in human xp11.2 and the conserved segment in mouse.
Tsuchiya KD, Greally JM, Yi Y, Noel KP, Truong JP, Disteche CM
(2004) Genome Res 14: 1275-84 - An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission.
Shirey JK, Xiang Z, Orton D, Brady AE, Johnson KA, Williams R, Ayala JE, Rodriguez AL, Wess J, Weaver D, Niswender CM, Conn PJ
(2008) Nat Chem Biol 4: 42-50 - Inhibition of pancreatic adenocarcinoma cell growth by lovastatin.
Sumi S, Beauchamp RD, Townsend CM, Uchida T, Murakami M, Rajaraman S, Ishizuka J, Thompson JC
(1992) Gastroenterology 103: 982-9 - Single-stranded DNA-binding proteins regulate the abundance of LIM domain and LIM domain-binding proteins.
Xu Z, Meng X, Cai Y, Liang H, Nagarajan L, Brandt SJ
(2007) Genes Dev 21: 942-55 - Kindlin-2 controls bidirectional signaling of integrins.
Montanez E, Ussar S, Schifferer M, Bösl M, Zent R, Moser M, Fässler R
(2008) Genes Dev 22: 1325-30 - Voltage-gated sodium channels are required for heart development in zebrafish.
Chopra SS, Stroud DM, Watanabe H, Bennett JS, Burns CG, Wells KS, Yang T, Zhong TP, Roden DM
(2010) Circ Res 106: 1342-50 - Informatic and functional approaches to identifying a regulatory region for the cardiac sodium channel.
Atack TC, Stroud DM, Watanabe H, Yang T, Hall L, Hipkens SB, Lowe JS, Leake B, Magnuson MA, Yang P, Roden DM
(2011) Circ Res 109: 38-46 - Differential expression of adenosine receptors in human endothelial cells: role of A2B receptors in angiogenic factor regulation.
Feoktistov I, Goldstein AE, Ryzhov S, Zeng D, Belardinelli L, Voyno-Yasenetskaya T, Biaggioni I
(2002) Circ Res 90: 531-8 - Functional effects of protein kinase C activation on the human cardiac Na+ channel.
Murray KT, Hu NN, Daw JR, Shin HG, Watson MT, Mashburn AB, George AL
(1997) Circ Res 80: 370-6 - Integrin cytoplasmic domains mediate inside-out signal transduction.
O'Toole TE, Katagiri Y, Faull RJ, Peter K, Tamura R, Quaranta V, Loftus JC, Shattil SJ, Ginsberg MH
(1994) J Cell Biol 124: 1047-59 - Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles.
Ktistakis NT, Brown HA, Waters MG, Sternweis PC, Roth MG
(1996) J Cell Biol 134: 295-306 - Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion.
Thoreson MA, Anastasiadis PZ, Daniel JM, Ireton RC, Wheelock MJ, Johnson KR, Hummingbird DK, Reynolds AB
(2000) J Cell Biol 148: 189-202 - Dynamics of putative raft-associated proteins at the cell surface.
Kenworthy AK, Nichols BJ, Remmert CL, Hendrix GM, Kumar M, Zimmerberg J, Lippincott-Schwartz J
(2004) J Cell Biol 165: 735-46 - N-cadherin regulates spatially polarized signals through distinct p120ctn and β-catenin-dependent signalling pathways.
Ouyang M, Lu S, Kim T, Chen CE, Seong J, Leckband DE, Wang F, Reynolds AB, Schwartz MA, Wang Y
(2013) Nat Commun 4: 1589 - Rsk2 allosterically activates estrogen receptor alpha by docking to the hormone-binding domain.
Clark DE, Poteet-Smith CE, Smith JA, Lannigan DA
(2001) EMBO J 20: 3484-94 - Inhibition of platelet aggregation by a monoclonal antibody against human fibronectin.
Dixit VM, Haverstick DM, O'Rourke K, Hennessy SW, Broekelmann TJ, McDonald JA, Grant GA, Santoro SA, Frazier WA
(1985) Proc Natl Acad Sci U S A 82: 3844-8 - Natural and synthetic prion structure from X-ray fiber diffraction.
Wille H, Bian W, McDonald M, Kendall A, Colby DW, Bloch L, Ollesch J, Borovinskiy AL, Cohen FE, Prusiner SB, Stubbs G
(2009) Proc Natl Acad Sci U S A 106: 16990-5 - N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl-D-aspartate receptor activity.
Sur C, Mallorga PJ, Wittmann M, Jacobson MA, Pascarella D, Williams JB, Brandish PE, Pettibone DJ, Scolnick EM, Conn PJ
(2003) Proc Natl Acad Sci U S A 100: 13674-9 - Structural organization of the functional domains of Clostridium difficile toxins A and B.
Pruitt RN, Chambers MG, Ng KK, Ohi MD, Lacy DB
(2010) Proc Natl Acad Sci U S A 107: 13467-72 - Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by site-2 protease.
Ye J, Davé UP, Grishin NV, Goldstein JL, Brown MS
(2000) Proc Natl Acad Sci U S A 97: 5123-8 - The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation.
Carricaburu V, Lamia KA, Lo E, Favereaux L, Payrastre B, Cantley LC, Rameh LE
(2003) Proc Natl Acad Sci U S A 100: 9867-72 - CLONAL GROWTH OF MAMMALIAN CELLS IN A CHEMICALLY DEFINED, SYNTHETIC MEDIUM.
HAM RG
(1965) Proc Natl Acad Sci U S A 53: 288-93 - A common polymorphism associated with antibiotic-induced cardiac arrhythmia.
Sesti F, Abbott GW, Wei J, Murray KT, Saksena S, Schwartz PJ, Priori SG, Roden DM, George AL, Goldstein SA
(2000) Proc Natl Acad Sci U S A 97: 10613-8 - Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks.
Rathmell WK, Chu G
(1994) Proc Natl Acad Sci U S A 91: 7623-7 - Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis.
Mourez M, Yan M, Lacy DB, Dillon L, Bentsen L, Marpoe A, Maurin C, Hotze E, Wigelsworth D, Pimental RA, Ballard JD, Collier RJ, Tweten RK
(2003) Proc Natl Acad Sci U S A 100: 13803-8 - In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia.
Skala MC, Riching KM, Gendron-Fitzpatrick A, Eickhoff J, Eliceiri KW, White JG, Ramanujam N
(2007) Proc Natl Acad Sci U S A 104: 19494-9 - Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen.
Cunningham K, Lacy DB, Mogridge J, Collier RJ
(2002) Proc Natl Acad Sci U S A 99: 7049-53 - Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A.
Ktistakis NT, Brown HA, Sternweis PC, Roth MG
(1995) Proc Natl Acad Sci U S A 92: 4952-6 - Crystal structure of human junctional adhesion molecule 1: implications for reovirus binding.
Prota AE, Campbell JA, Schelling P, Forrest JC, Watson MJ, Peters TR, Aurrand-Lions M, Imhof BA, Dermody TS, Stehle T
(2003) Proc Natl Acad Sci U S A 100: 5366-71 - A chimeric adenovirus vector encoding reovirus attachment protein sigma1 targets cells expressing junctional adhesion molecule 1.
Mercier GT, Campbell JA, Chappell JD, Stehle T, Dermody TS, Barry MA
(2004) Proc Natl Acad Sci U S A 101: 6188-93 - Genetics of somatic mammalian cells, VII. Induction and isolation of nutritional mutants in Chinese hamster cells.
Kao FT, Puck TT
(1968) Proc Natl Acad Sci U S A 60: 1275-81 - Cell type-specific integrin variants with alternative alpha chain cytoplasmic domains.
Tamura RN, Cooper HM, Collo G, Quaranta V
(1991) Proc Natl Acad Sci U S A 88: 10183-7 - Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion.
Kinley AW, Weed SA, Weaver AM, Karginov AV, Bissonette E, Cooper JA, Parsons JT
(2003) Curr Biol 13: 384-93
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